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Irvine, Katharine M., Burns, Christopher J., Wilks, Andrew F., Su, Stephen, Hume, David A. and Sweet, Matthew J. (2006) A CSF-1 receptor kinase inhibitor targets effector functions and inhibits pro-inflammatory cytokine production from murine macrophage populations. The FASEB Journal, 20 11: 1921-1923. doi:10.1096/fj.06-5848fje 142   49 Cited 17 times in Scopus17 7
Schroder, Kate, Sagulenko, Vitaliya, Zamoshnikova, Alina, Richards, Ayanthi A., Cridland, Jasmyn A., Irvine, Katharine M., Stacey, Katryn J. and Sweet, Matthew J. (2012) Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction. Immunobiology, 217 12: 1325-1329. doi:10.1016/j.imbio.2012.07.020 112 53 21 Cited 26 times in Scopus26 0
Irvine, Katharine M., Burns, Christopher J., Wilks, Andrew F., Bu, Xiangyong, Harte, Michael F., Su, Stephen, Hume, David A. and Sweet, Matthew J. (2005). A potent CSF-1 Receptor tyrosine kinase inhibitor targets survival and effector functions in marine macrophage populations. In: Inflammation Research. , , (S148-S148). . 23   0
Fagan, K., Irvine, K., Kumar, S., Bates, A., Horsfall, L., Feeney, G. and Powell, E. (2013). Assessment of alcohol histories obtained from patients with liver disease: Opportunities to improve early intervention. In: Australian Gastroenterology Week 2013, Melbourne, Australia, (61-61). 7-9 October 2013. doi:10.1111/jgh.12365_5 15   0 1
Fagan, K., Irvine, K., McWhinney, B., Fletcher, L., Horsfall, L., Johnson, L., Clouston, A., Jonsson, J., O'Rourke, P., Martin, J., Pretorius, C., Ungerer, J. and Powell, E. (2013). BMI but not aetiology or stage of liver disease affects the diagnostic sensitivity of carbohydrate deficient transferrin. In: International Liver Congress / 48th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Amsterdam Netherlands, (S215-S215). 24-28 April 2013. doi:10.1016/S0168-8278(13)60527-9 35   0 0
Fagan, Kevin J., Irvine, Katharine M., McWhinney, Brett C., Fletcher, Linda M., Horsfall, Leigh U., Johnson, Lambro A., Clouston, Andrew D., Jonsson, Julie R., O'Rourke, Peter, Martin, Jennifer, Pretorius, Carel J., Ungerer, Jacobus P. J. and Powell, Elizabeth E. (2013) BMI But Not Stage or Etiology of Nonalcoholic Liver Disease Affects the Diagnostic Utility of Carbohydrate-Deficient Transferrin. Alcoholism Clinical and Experimental Research, 37 10: 1771-1778. doi:10.1111/acer.12143 33   2 Cited 2 times in Scopus2 0
Fagan, K. J., Zhao, Eileen Y., Horsfall, L. U., Ruffin, Brittany J., Kruger, Mark S., McPhail, S. M., O'Rourke, Peter, Ballard, Emma, Irvine, K. M. and Powell, E. E. (2014) Burden of decompensated cirrhosis and ascites on hospital services in a tertiary care facility: time for change?. Internal Medicine Journal, 44 9: 865-872. doi:10.1111/imj.12491 36   0 Cited 0 times in Scopus0 3
Irvine, Katharine M., Andrews, Melanie R., Fernandez-Rojo, Manuel A., Schroder, Kate, Burns, Christopher J., Su, Stephen, Wilks, Andrew F., Parton, Robert G., Hume, David A. and Sweet, Matthew J. (2009) Colony-stimulating factor-1 (CSF-1) delivers a proatherogenic signal to human macrophages. Journal of Leukocyte Biology, 85 2: 278-288. doi:10.1189/jlb.0808497 77   28 Cited 30 times in Scopus30 0
Schroder, Kate, Irvine, Katharine M., Taylor, Martin S., Bokil, Nilesh J., Le Cao, Kim-Anh, Masterman, Kelly-Anne, Labzin, Larisa I., Semple, Colin A., Kapetanovic, Ronan, Fairbairn, Lynsey, Akalin, Altuna, Faulkner, Geoffrey J., Baillie, John Kenneth, Gongora, Milena, Daub, Carsten O., Kawaji, Hideya, McLachlan, Geoffrey J., Goldman, Nick, Grimmond, Sean M., Carninci, Piero, Suzuki, Harukazu, Hayashizaki, Yoshihide, Lenhard, Boris, Hume, David A. and Sweet, Matthew J. (2012) Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages. Proceedings of the National Academy of Sciences of the USA, 109 16: E944-E953. doi:10.1073/pnas.1110156109 101   37 Cited 43 times in Scopus43 3
Mar, Jessica C., Kimura, Yasumasa, Schroder, Kate, Irvine, Katherine M., Hayashizaki, Yoshihide, Suzuki, Harukazu, Hume, David and Quackenbush, John (2009) Data-driven normalization strategies for high-throughput quantitative RT-PCR. BMC Bioinformatics, 10 110.1-110.10. doi:10.1186/1471-2105-10-110 58   33 Cited 39 times in Scopus39 0
Maeda, N, Nishiyori, H, Nakamura, M, Kawazu, C, Murata, M, Sano, H, Hayashida, K, Fukuda, S, Tagami, M, Hasegawa, A, Murakami, K, Schroder, K, Irvine, K, Hume, DA, Hayashizaki, Y, Carninci, P and Suzuki, H (2008) Development of a DNA barcode tagging method for monitoring dynamic changes in gene expression by using an ultra high-throughput sequencer. Biotechniques, 45 1: 95-97. doi:10.2144/000112814 48   21 Cited 19 times in Scopus19 0
Fagan K.J., Irvine K.M., McWhinney B.C., Fletcher L.M., Horsfall L.U., Johnson L., O'Rourke P., Martin J., Scott I., Pretorius C.J., Ungerer J.P.J. and Powell E.E. (2014) Diagnostic sensitivity of carbohydrate deficient transferrin in heavy drinkers. BMC Gastroenterology, 14 1: 1-6. doi:10.1186/1471-230X-14-97 16   0 Cited 1 times in Scopus1 1
Schroder, K., Spille, M., Pilz, A., Lattin, J., Bode, K. A., Irvine, K. M., Burrows, A. D., Ravasi, T., Weighardt, H., Stacey, K. J., Decker, T., Hume, D. A., Dalpke, A. H. and Sweet, M. J. (2007) Differential effects of CpG DNA on IFN-beta induction and STAT1 activation in murine macrophages versus dendritic cells: Alternatively activated STAT1 negatively regulates TLR signaling in macrophages. Journal of Immunology, 179 6: 3495-3503. 160   29 Cited 28 times in Scopus28
Halili, Maria A., Andrews, Melanie R., Labzin, Larisa I., Schroder, Kate, Matthias, Gabriele, Cao, Chun, Lovelace, Erica, Reid, Robert C., Le, Giang T., Hume, David A., Irvine, Katharine M., Matthias, Patrick, Fairlie, David P. and Sweet, Matthew J. (2010) Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS. Journal of Leukocyte Biology, 87 6: 1103-1114. doi:10.1189/jlb.0509363 118   52 Cited 55 times in Scopus55 0
Zhao, E., Horsfall, L., Ruffin, B. J., Fagan, K. J., Irvine, K. M. and Powell, E. E. (2013). Factors associated with mortality and unplanned hospital readmissions in patients with ascites. In: Australian Gastroenterology Week 2013, Melbourne, Australia, (79-80). 7-9 October 2013. doi:10.1111/jgh.12365_5 23   0 1
Sweet, M. J., Schroder, K., Irvine, K. M., Taylor, M., Bokil, N. J., Broomfield, S., Schembri, M. A., Stacey, K. J. and Hume, D. A. (2012). Functional significance of evolutionary divergence in Toll-like receptor-regulated gene expression in human versus mouse. In: Abstracts of the European Congress of Immunology. European Congress of Immunology, Glasgow, Scotland, (297-297). 5-8 September 2012. doi:10.1111/imm.12002 44   0 0
Ripoll, Vera M., Irvine, Katharine M., Ravasi, Timothy, Sweet, Matthew J. and Hume, David A. (2007) Gpnmb is induced in macrophages by IFN-gamma and lipopolysaccharide and acts as a feedback regulator of proinflammatory responses. Journal of Immunology, 178 10: 6557-6566. 108   54 Cited 53 times in Scopus53
Shakespear, Melanie R., Hohenhaus, Daniel M., Kelly, Greg M., Kamal, Nabilah A., Gupta, Praveer, Labzin, Larisa I., Schroder, Kate, Garceau, Valerie, Barbero, Sheila, Iyer, Abishek, Hume, David A., Reid, Robert C., Irvine, Katharine M., Fairlie, David P. and Sweet, Matthew J. (2013) Histone deacetylase 7 promotes Toll-like Receptor 4-dependent pro-inflammatory gene expression in macrophages. Journal of Biological Chemistry, 288 35: 25362-25374. doi:10.1074/jbc.M113.496281 56   5 Cited 4 times in Scopus4 0
Shakespear, Melanie R., Halili, Maria A., Irvine, Katharine M., Fairlie, David P. and Sweet, Matthew J. (2011) Histone deacetylases as regulators of inflammation and immunity. Trends in Immunology, 32 7: 335-343. doi:10.1016/j.it.2011.04.001 58   91 Cited 90 times in Scopus90 0
Irvine, Katharine M., Schroder, Elizabeth E. and Powell, Elizabeth E. (2012) Liver repercussions of defective gut surveillance. Hepatology, 56 3: 1174-1177. doi:10.1002/hep.25944 47   1 Cited 1 times in Scopus1 0
Van Zuylen, Wendy J., Garceau, Valerie, Idris, Adi, Schroder, Kate, Irvine, Katharine M., Lattin, Jane E., Ovchinnikov, Dmitry A., Perkins, Andrew C., Cook, Andrew D., Hamilton, John A., Hertzog, Paul J., Stacey, Katryn J., Kellie, Stuart, Hume, David A. and Sweet, Matthew J. (2011) Macrophage activation and differentiation signals regulate Schlafen-4 gene expression: Evidence for Schlafen-4 as a modulator of myelopoiesis. PLoS One, 6 1: e15723-1-e15723-13. doi:10.1371/journal.pone.0015723 117   13 Cited 12 times in Scopus12 0
Clouston, Andrew D., Gadd, Victoria L., Irvine, Katharine M. and Powell, Elizabeth E. (2014) New paradigms in the histopathology of NAFLD. Current Hepatitis Reports, 13 2: 81-87. doi:10.1007/s11901-014-0214-x 23   Cited 0 times in Scopus0 0
Irvine, Katharine M., Gallego, Patricia, An, Xiaoyu, Best, Shannon E., Thomas, Gethin, Wells, Christine, Harris, Mark, Cotterill, Andrew and Thomas, Ranjeny (2012) Peripheral blood monocyte gene expression profile clinically stratifies patients with recent-onset type 1 diabetes. Diabetes, 61 5: 1281-1290. doi:10.2337/db11-1549 105 1 7 Cited 6 times in Scopus6 0
Gadd, Victoria L., Melino, Michelle, Roy, Sandrine, Horsfall, Leigh, O'Rourke, Peter, Williams, Millicent R., Irvine, Katharine M., Sweet, Matthew J., Jonsson, Julie R., Clouston, Andrew D. and Powell, Elizabeth E. (2013) Portal, but not lobular, macrophages express matrix metalloproteinase-9: association with the ductular reaction and fibrosis in chronic hepatitis C. Liver International, 33 4: 569-579. doi:10.1111/liv.12050 66   9 Cited 12 times in Scopus12 0
Schroder, Kate, Lichtinger, Monika, Irvine, Katharine M., Brion, Kristian, Trieu, Angela, Ross, Ian L., Ravasi, Timothy, Stacey, Katryn J., Rehli, Michael, Hume, David A. and Sweet, Matthew J. (2007) PU.1 and ICSBP control constitutive and IFN-gamma-regulated Tlr9 gene expression in mouse macrophages. Journal of Leukocyte Biology, 81 6: 1577-1590. doi:10.1189/jlb.0107036 89   27 Cited 30 times in Scopus30 0
Schroder, Kate, Irvine, Katharine M., Biron, Kristian, Lichtinger, Monika, Ravasi, Timothy, Rehli, Michael, Sweet, Matthen J. and Hume, David A. (2005). PU.1 and ICSBP regulate the tlr9 promoter in mouse macrophages. In: Inflammation Research. , , (S186-S187). . 18   0
Irvine, K., Stirling, R., Hume, D. and Kennedy, D. (2004) Rasputin, more promiscuous than ever: a review of G3BP. International Journal of Developmental Biology, 48 10: 1065-1077. doi:10.1387/ijdb.041893ki 71   65 Cited 67 times in Scopus67 3
Yu, C.-H., Nguyen, T.T.K., Irvine, K.M., Sweet, M.J., Frazer, I.H. and Blumenthal, A. (2014) Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4. European Journal of Immunology, 44 5: 1480-1490. doi:10.1002/eji.201343959 30   0 Cited 0 times in Scopus0 1
Goh, Felicia, Irvine, Katharine M., Lovelace, Erica, Donnelly, Sheila, Jones, Malcolm K ., Brion, Kristian, Hume, David A., Kotze, Andrew C., Dalton John P., Ingham, Aaron and Sweet, Matthew J. (2009) Selective induction of the Notch ligand Jagged -1 in macrophages by soluble egg antigen from Schistosoma mansoni involves ERK signaling. Immunology, 127 3: 326-337. doi:10.1111/j.1365-2567.2008.02979.x 130   16 Cited 18 times in Scopus18 0
Irvine, Katharine M., Skoien, Richard, Bokil, Nilesh J., Melino, Michelle, Thomas, Gethin P., Loo, Dorothy, Gabrielli, Brian, Hill, Michelle M., Sweet, Matthew J., Clouston, Andrew D. and Powell, Elizabeth E. (2014) Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration. World Journal of Gastroenterology, 20 47: 17851-17862. doi:10.3748/wjg.v20.i47.17851 17   0 Cited 0 times in Scopus0 1
Kubosaki, A, Lindgren, G, Tagami, M, Simon, C, Tomaru, Y, Miura, H, Suzuki, T, Arner, E, Forrest, ARR, Irvine, KM, Schroder, K, Hasegawa, Y, Kanamori-Katayama, M, Rehli, M, Hume, DA, Kawai, J, Suzuki, M, Suzuki, H and Hayashizaki, Y (2010) The combination of gene perturbation assay and ChIP-chip reveals functional direct target genes for IRF8 in THP-1 cells. Molecular Immunology, 47 14: 2295-2302. doi:10.1016/j.molimm.2010.05.289 89   13 Cited 12 times in Scopus12 0
Irvine, Katharine Margaret. (2004). The expression and function of G3BPs in macrophages PhD Thesis, Institute for Molecular Bioscience, The University of Queensland. 68 4
Kawaji, H, Severin, J, Lizio, M, Waterhouse, A, Katayama, S, Irvine, K. M., Hume, D. A., Forrest, A. R. R., Suzuki, H, Carninci, P, Hayashizaki, Y and Daub, C. O. (2009) The FANTOM web resource: from mammalian transcriptional landscape to its dynamic regulation. Genome Biology, 10 4: x-x. doi:10.1186/gb-2009-10-4-r40 50   34 Cited 36 times in Scopus36 6
Irvine, Katharine M., Andrews, Melanie R., Fernandez, Manuel A., Parton, Robert G., Burns, Christopher J., Su, Stephen, Wilks, Andrew F., Hume, David A. and Sweet, M. J. (2008). The identification of novel CSF-1 target genes in human macrophages. In: Cytokine. 7th Joint Conference of the International-Cytokine-Society/International-Society-for-Interferon-and-Cytoklin-Research, Montreal Canada, (245-245). Oct 12-16, 2008. doi:10.1016/j.cyto.2008.07.078 17   0 0
Hume, D. A., Irvine, K. M. and Schroder, K. (2009). The impact of CAGE data on the understanding of macrophage transcriptional biology. In Piero Carninci (Ed.), Cap- Analysis Gene Expression (Cage): The Science of Decoding Gene Transcription (pp. 227-244) Singapore: Pan Stanford Publishing. 50   0
Gadd, V., Skoien, R., Fagan, K., Irvine, K., Powell, E. and Clouston, A. (2013). The portal inflammatory infiltrate and ductular niche in non-alcoholic fatty liver disease. In: Australian Gastroenterology Week 2013, Melbourne Australia, (9-10). 7-9 October 2013. doi:10.1111/jgh.12365 28   0 1
Gadd, Victoria L., Skoien, Richard, Powell, Elizabeth E., Fagan, Kevin J., Winterford, Clay, Horsfall, Leigh, Irvine, Katharine and Clouston, Andrew D. (2014) The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease. Hepatology, 59 4: 1393-1405. doi:10.1002/hep.26937 19   0 Cited 8 times in Scopus8 0
Faulkner, Geoffrey J., Kimura, Yasumasa, Daub, Carsten O., Wani, Shivangi, Plessy, Charles, Irvine, Katharine M., Schroder, Kate, Cloonan, Nicole, Steptoe, Anita L., Lassmann, Timo, Waki, Kazunori, Hornig, Nadine, Arakawa, Takahiro, Takahashi, Hazuki, Kawai, Jun, Forrest, Alistair R. R., Suzuki, Harukazu, Hayashizaki, Yoshihide, Hume, David A., Orlando, Valerio, Grimmond, Sean M. and Carninci, Piero (2009) The regulated retrotransposon transcriptome of mammalian cells. Nature genetics, 41 5: 563-571. doi:10.1038/ng.368 111   245 Cited 248 times in Scopus248 2
Suzuki, H, Forrest, ARR, van Nimwegen, E, Daub, CO, Balwierz, PJ, Irvine, KM, Lassmann, T, Ravasi, T, Hasegawa, Y, de Hoon, MJL, Katayama, S, Schroder, K, Carninci, P, Tomaru, Y, Kanamori-Katayama, M, Kubosaki, A, Akalin, A, Ando, Y, Arner, E, Asada, M, Asahara, H, Bailey, T, Bajic, VB, Bauer, D, Beckhouse, AG, Bertin, N, Bjorkegren, J, Brombacher, F, Bulger, E, Chalk, AM, Chiba, J, Cloonan, N, Dawe, A, Dostie, J, Engstrom, PG, Essack, M, Faulkner, GJ, Fink, JL, Fredman, D, Fujimori, K, Furuno, M, Gojobori, T, Gough, J, Grimmond, SM, Gustafsson, M, Hashimoto, M, Hashimoto, T, Hatakeyama, M, Heinzel, S, Hide, W, Hofmann, O, Hornquist, M, Huminiecki, L, Ikeo, K, Imamoto, N, Inoue, S, Inoue, Y, Ishihara, R, Iwayanagi, T, Jacobsen, A, Kaur, M, Kawaji, H, Kerr, MC, Kimura, R, Kimura, S, Kimura, Y, Kitano, H, Koga, H, Kojima, T, Kondo, S, Konno, T, Krogh, A, Kruger, A, Kumar, A, Lenhard, B, Lennartsson, A, Lindow, M, Lizio, M, MacPherson, C, Maeda, N, Maher, CA, Maqungo, M, Mar, J, Matigian, NA, Matsuda, H, Mattick, JS, Meier, S, Miyamoto, S, Miyamoto-Sato, E, Nakabayashi, K, Nakachi, Y, Nakano, M, Nygaard, S, Okayama, T, Okazaki, Y, Okuda-Yabukami, H, Orlando, V, Otomo, J, Pachkov, M, Petrovsky, N, Plessy, C, Quackenbush, J, Radovanovic, A, Rehli, M, Saito, R, Sandelin, A, Schmeier, S, Schonbach, C, Schwartz, AS, Semple, CA, Sera, M, Severin, J, Shirahige, K, Simons, C, Laurent, GS, Suzuki, M, Suzuki, T, Sweet, MJ, Taft, RJ, Takeda, S, Takenaka, Y, Tan, K, Taylor, MS, Teasdale, RD, Tegner, J, Teichmann, S, Valen, E, Wahlestedt, C, Waki, K, Waterhouse, A, Wells, Christine A., Winther, O, Wu, L, Yamaguchi, K, Yanagawa, H, Yasuda, J, Zavolan, M, Hume, DA, Arakawa, T, Fukuda, S, Imamura, K, Kai, C, Kaiho, A, Kawashima, T, Kawazu, C, Kitazume, Y, Kojima, M, Miura, H, Murakami, K, Murata, M, Ninomiya, N, Nishiyori, H, Noma, S, Ogawa, C, Sano, T, Simon, C, Tagami, M, Takahashi, Y, Kawai, J, Hayashizaki, Y, FANTOM Consortium and Riken Omics Science Center (2009) The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nature Genetics, 41 5: 553-562. doi:10.1038/ng.375 162 2 201 Cited 205 times in Scopus205 6
Taft, RJ, Glazov, EA, Cloonan, N, Simons, C, Stephen, S, Faulkner, GJ, Lassmann, T, Forrest, ARR, Grimmond, SM, Schroder, K, Irvine, K, Arakawa, T, Nakamura, M, Kubosaki, A, Hayashida, K, Kawazu, C, Murata, M, Nishiyori, H, Fukuda, S, Kawai, J, Daub, CO, Hume, DA, Suzuki, H, Orlando, V, Carninci, P, Hayashizaki, Y and Mattick, JS (2009) Tiny RNAs associated with transcription start sites in animals. Nature Genetics, 41 5: 572-578. doi:10.1038/ng.312 105   187 Cited 207 times in Scopus207 2
Kawaji, H, Severin, J, Lizio, M, Forrest, ARR, van Nimwegen, E, Rehli, M, Schroder, K, Irvine, K, Suzuki, H, Carninci, P, Hayashizaki, Y and Daub, CO (2011) Update of the FANTOM web resource: From mammalian transcriptional landscape to its dynamic regulation. Nucleic Acids Research, 39 Supp. 1: D856-D860. doi:10.1093/nar/gkq1112 48   17 Cited 22 times in Scopus22 0