Browse by all authors Browse By Author ID - Khromykh, Alexander

Browse Results (120 results found)

Subscribe to the RSS feed for this result setSubscribe to the RSS feed for this result set

Page 1 of 3

Result Pages:    1 2 3  next › last »

Refine

  Abstract Views File Downloads Thomson Reuters Web of Science Citation Count Scopus Citation Count Altmetric Score
Mackenzie, J. M., Khromykh, A. and Parton, R. G. (2005). A bigmac a day keeps the flavivirus away. In: 3rd Australian Virology Group Meeting. 3rd Australian Virology Group Meeting, Phillip Is, (31-31). 9-12 Dec, 2005. 161  
Pijlman, Gorben P., Funk, Anneke, Kondratieva, Natasha, Leung, Jason, Torres, Shessy, Van der Aa, Lieke, Liu, Wen Jun, Palmenberg, Ann C., Shi, Pei-Yong, Hall, Roy A. and Khromykh, Alexander A. (2008) A highly structured,nuclease-resistant, noncoding RNA produced by flaviviruses is required for pathogenicity. Cell Host and Microbe, 4 6: 579-591. doi:10.1016/j.chom.2008.10.007 104   81 Cited 89 times in Scopus89 4
Hoang-Le, D., Smeenk, L., Anraku, I., Pijlman, G. P., Wang, X. J., De Vrij, J., Liu, W. J., Le, T. T., Schroder, W. A., Khromykh, Alexander A. and Suhrbier, A. (2009) A Kunjin replicon vector encoding granulocyte macrophage colony-stimulating factor for intra-tumoral gene therapy. Gene Therapy, 16 2: 190-199. doi:10.1038/gt.2008.169 93   6 Cited 5 times in Scopus5 0
Pyankov, Oleg V., Bodnev, Sergey A., Pyankova, Olga G., Solodkyi, Vladislav V., Pyankov, Stepan A., Setoh, Yin Xiang, Volchkova, Valentina A., Suhrbier, Andreas, Volchkov, Viktor V., Agafonov, Alexander A. and Khromykh, Alexander A. (2015) A Kunjin replicon virus-like particle vaccine provides protection against ebola virus infection in nonhuman primates. Journal of Infectious Diseases, Supp.: S1-S4. doi:10.1093/infdis/jiv019 17   19
Liu, Wen Jun, Chen, Hua Bo, Xiang, Ju Wang, Huang, Hester and Khromykh, Alexander A. (2004) Analysis of adaptive mutations in Kunjin virus replicon RNA reveals a novel role for the flavivirus nonstructural protein NS2A in inhibition of beta interferon promoter-driven transcription. Journal of Virology, 78 22: 12225-12235. doi:10.1128/JVI.78.22.12225-12235.2004 70   2 Cited 72 times in Scopus72 0
Tan, Cindy S. E., Hobson-Peters, Jody M., Stoermer, Martin J., Fairlie, David P., Khromykh, Alexander A. and Hall, Roy A. (2013) An interaction between the methyltransferase and RNA dependent RNA polymerase domains of the West Nile virus NS5 protein. Journal of General Virology, 94 Pt. 9: 1961-1971. doi:10.1099/vir.0.054395-0 49   4 Cited 4 times in Scopus4 0
Moon, Stephanie L., Anderson, John R., Kumagai, Yutaro, Wilusz, Carol J., Akira, Shizuo, Khromykh, Alexander A. and Wilusz, Jeffrey (2012) A noncoding RNA produced by arthropod-borne flaviviruses inhibits the cellular exoribonuclease XRN1 and alters host mRNA stability. RNA, 18 11: 2029-2040. doi:10.1261/rna.034330.112 34   26 Cited 30 times in Scopus30 4
Edmonds, Judith, van Grinsven, Erinke, Prow, Natalie, Bosco-Lauth, Angela, Brault, Aaron C., Bowen, Richard A., Hall, Roy and Khromykh, Alexander A. (2013) A novel bacteria-free method for generation of flavivirus infectious DNA by circular polymerase extension reaction allows accurate recapitulation of viral heterogeneity. Journal of Virology, 87 4: 2367-2372. doi:10.1128/JVI.03162-12 70   6 Cited 6 times in Scopus6 0
Liu, W., Wang, D.Z., Clark, M., Lobigs, M. and Khromykh, A. (2005). A single amino acid in the West Nile virus nonstructural protein NS2A disables its ability to inhibit interferon alpha/beta induction and attenuates virus virulence in mice. In: 3rd Australian Virology Group Meeting. 3rd Australian Virology Group Meeting, Phillip Is, (31-31). 9-12 Dec, 2005. 62  
Liu, Wen Jun, Wang, Xiang Ju, Clark, David C., Lobigs, Mario, Hall, Roy A. and Khromykh, Alexander A. (2006) A single amino acid substitution in the west nile virus nonstructural protein NS2A disables its ability to inhibit alpha/beta interferon induction and attenuates virus virulence in mice. Journal of Virology, 80 5: 2396-2404. doi:10.1128/JVI.80.5.2396-2404.2006 92   107 Cited 102 times in Scopus102 0
Scherret, J., Mackenzie, J. S., Khromykh, A. and Hall, R. A. (2001) Biological significance of glycosylation of the envelope protein of Kunjin virus. Annals of the New York Academy of Sciences, 951 West Nile Virus: Detection, Surveillance, And Control: 361-363. doi:10.1111/j.1749-6632.2001.tb02719.x 47   36 0
Frost, Melinda J., Zhang, Jing, Edmonds, Judith H., Prow, Natalie A., Gu, Xingnian, Davis, Rodney, Hornitzky, Christine, Arzey, Kathleen E., Finlaison, Deborah, Hick, Paul, Read, Andrew, Hobson-Peters, Jody, May, Fiona J., Doggett, Stephen L., Haniotis, John, Russell, Richard C., Hall, Roy A., Khromykh, Alexander A. and Kirkland, Peter D. (2012) Characterization of virulent West Nile virus Kunjin Strain, Australia, 2011. Emerging Infectious Diseases, 18 5: 792-800. doi:10.3201/eid1805.111720 85   33 Cited 33 times in Scopus33 0
Fros, JJ, Liu, WJ, Prow, NA, Geertsema, C, Ligtenberg, M, Vanlandingham, DL, Schnettler, E, Vlak, JM, Suhrbier, A, Khromykh, AA and Pijlman, GP (2010) Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling. Journal of Virology, 84 20: 10877-10887. doi:10.1128/JVI.00949-10 54   46 Cited 51 times in Scopus51 3
Mackenzie, J M, Khromykh, A and Parton, R G (2006). Cholesterol is good, just ask the flaviviruses. In: Annual Scientific Meeting & Exhibition - Aust Society for Microbiology. Annual Scientific Meeting & Exhibition - Aust Society for Micry, Gold Coast, (Abstract). 2-6 July, 2006. 61  
Mackenzie, Jason M., Khromykh, Alexander and Parton, Robert G. (2007) Cholesterol Manipulation by West Nile Virus Perturbs the Cellular Immune Response. Cell Host and Microbe, 2 4: 229-239. doi:10.1016/j.chom.2007.09.003 56   95 Cited 90 times in Scopus90 0
Khromykh, Alexander A., Sedlak, Petra L. and Westaway, Edwin G. (2000) cis- and trans- Acting Elements in Flavivirus RNA Replication. Journal of Virology, 74 7: 3253-3263. doi:10.1128/JVI.74.7.3253-3263.2000 71   100 Cited 95 times in Scopus95 0
Selisko, B., Dutartre, H., Guillemot, J. C., Debarnot, C., Benarroch, D., Khromykh, A., Despres, P., Egloff, M. P. and Canard, B. (2006) Comparative mechanistic studies of de novo RNA synthesis by flavivirus RNA-dependent RNA polymerases. Virology, 351 1: 145-158. doi:10.1016/j.virol.2006.03.026 87   60 Cited 64 times in Scopus64 0
Liu, W. J., Sedlak, P. L., Kondratieva, N. and Khromykh, A. A. (2002) Complementation analysis of the flavivirus Kunjin NS3 and NS5 proteins defines the minimal regions essential for formation of a replication complex and shows a requirement of NS3 in cis for virus assembly. Journal of Virology, 76 21: 10766-10775. doi:10.1128/JVI.76.21.10766-10775.2002 52   61 Cited 58 times in Scopus58 0
Pugachev, KV, Schwaiger, J, Brown, N, Zhang, ZX, Catalan, J, Mitchell, FS, Ocran, SW, Rumyantsev, AA, Khromykh, AA, Monath, TP and Guirakhoo, F (2007) Construction and biological characterization of artificial recombinants between a wild type flavivirus (Kunjin) and a live chimeric flavivirus vaccine (ChimeriVax-JE). Vaccine, 25 37-38: 6661-6671. doi:10.1016/j.vaccine.2007.07.016 83   13 Cited 11 times in Scopus11 0
Khromykh, A. A., Varnavski, A. N., Sedlak, P. L. and Westaway, E. G. (2001) Coupling between replication and packaging of flavivirus RNA: Evidence derived from the use of DNA-based full-length cDNA clones of kunjin virus. Journal of Virology, 75 10: 4633-4640. doi:10.1128/JVI.75.10.4633-4640.2001 45   93 Cited 89 times in Scopus89 0
Mastrangelo, E, Milani, M, Bollati, M, Selisko, B, Peyrane, F, Pandini, V, Sorrentino, G, Canard, B, Konarev, PV, Svergun, DI, de Lamballerie, X, Coutard, B, Khromykh, AA and Bolognesi, M (2007) Crystal structure and activity of Kunjin virus NS3 helicase; Protease and helicase domain assembly in the full length NS3 protein. Journal of Molecular Biology, 372 2: 444-455. doi:10.1016/j.jmb.2007.06.055 61   35 Cited 37 times in Scopus37 0
Malet, H., Egloff, M., Selisko, B., Butcher, R., Wright, P., Roberts, M., Gruez, A., Sulzenbacher, G., Vonrhein, C., Bricogne, G., Mackenzie, J., Khromykh, A., Davidson, A. and Canard, B. (2007) Crystal structure of the RNA polymerase domain of the West Nile Virus non-structural protein 5. The Journal of Biological Chemistry, 282 14: 10678-10689. doi:10.1074/jbc.M607273200 80   105 Cited 107 times in Scopus107 1
Prow, Natalie A., May, Fiona J., Westlake, Daniel J., Hurrelbrink, Robert J., Biron, Rebecca M., Leung, Jason Y., McMinn, Peter C., Clark, David C., Mackenzie, John S., Lobigs, Mario, Khromykh, Alexander A. and Hall, Roy A. (2011) Determinants of attenuation in the envelope protein of the flavivirus Alfuy. Journal of General Virology, 92 10: 2286-2296. doi:10.1099/vir.0.034793-0 57   4 Cited 4 times in Scopus4 0
Hall, R. A., Nisbet, D. J., Pham, K.B., Pyke, A. T., Smith, G. A. and Khromykh, A. (2003) DNA vaccine coding for the full-length infectious Kunjin virus RNA protects mice against the New York strain of West Nile virus. Proceedings of The National Academy of Sciences of The United States of America, 100 18: 10460-10464. doi:10.1073/pnas.1834270100 75   65 Cited 66 times in Scopus66 0
Hall, RA and Khromykh, AA (2007) Drug evaluation: ChimeriVax-West Nile vaccine. Current Opinion In Molecular Therapeutics, 9 5: 498-504. 87   9 Cited 12 times in Scopus12
Alazard-Dany, N., Volchkova, V., Reynard, O., Carbonnelle, C., Dolnik, O., Ottmann, M., Khromykh, A. and Volchkov, V. E. (2006) Ebola virus glycoprotein GP is not cytotoxic when expressed constitutively at a moderate level. Journal of General Virology, 87 5: 1247-1257. doi:10.1099/vir.0.81361-0 71   33 Cited 37 times in Scopus37 16
Hussain, Mazhar, Lu, Guangjin, Torres, Shessy, Edmonds, Judith H., Kay, Brian H., Khromykh, Alexander A. and Asgari, Sassan (2013) Effect of Wolbachia on replication of West Nile Virus in mosquito cell line and adult mosquitoes. Journal of Virology, 87 2: 851-858. doi:10.1128/JVI.01837-12 46   14 Cited 14 times in Scopus14 2
Khromykh, Alexander A., Sedlak, Petra L., Guyatt, Kimberley J., Hall, Roy A. and Westaway, Edwin G. (1999) Efficient trans-complementation of the flavivirus kunjin NS5 protein but not of the NS1 protein requires its coexpression with other components of the viral replicase. Journal of Virology, 73 12: 10272-10280. 101   64
Khromykh, Alexander A., Meka, Hedije, Guyatt, Kimberley J. and Westaway, Edwin G. (2001) Essential role of cyclization sequences in Flavivirus RNA replication. Journal of Virology, 75 14: 6719-6728. doi:10.1128/JVI.75.14.6719-6728.2001 61   218 Cited 218 times in Scopus218 0
Kent, Stephen J., De Rose, Robert, Mokhonov, Vlad V., Mokhonova, Ekaterina I., Fernandez, Caroline S., Alcantara, Sheilajen, Rollman, Erik, Mason, Rosemarie D., Loh, Liyen, Peut, Viv, Reece, Jeanette C., Wang, Xiang Ju, Wilson, Kim M., Suhrbier, Andreas and Khromykh, Alexander (2008) Evaluation of recombinant Kunjin replicon SIV vaccines for protective efficacy in macaques. Virology, 374 2: 528-534. doi:10.1016/j.virol.2008.01.006 59   16 Cited 19 times in Scopus19 0
Khromykh, A. (2009). Evasion of host innate immune response by West Nile virus.. In: TLROZ 2009: Patterns Recognition Receptors in Health and Disease, Surfers Paradise, Australia, (). 28-30 October 2009. 59  
Guyatt, K. J., Westaway, E. G. and Khromykh, A. A. (2001) Expression and purification of enzymatically active recombinant RNA-dependent RNA polymerase (NS5) of the flavivirus Kunjin. Journal of Virological Methods, 92 1: 37-44. doi:10.1016/S0166-0934(00)00270-6 40   67 Cited 69 times in Scopus69 0
Slonchak, Andrii, Hussain, Mazhar, Torres Morales, Shessy, Asgari, Sassan and Khromykh, Alexander (2014) Expression of mosquito microRNA aae-miR-2940-5p is down-regulated in response to West Nile Virus infection to restrict viral replication. Journal of Virology, 88 15: 8457-8467. doi:10.1128/JVI.00317-14 48   4 Cited 3 times in Scopus3 1
Funk, A., Pijlman, G.P., Kondratieva, N., Leung, J., Van der Aa, L., Liu, W., Palmenberg, A.C., Shi, P.-Y., Hall, R.A. and Khromykh, A. (2008). Flaviviruses employ cellular mRNA decay machinery to generate subgenomic non-coding RNA required for pathogenicity. In: Arbovirus Research in Australia Meeting, Coffs Harbour, Australia, (). 15-19 Sept, 2008. 181  
Pijlman, G.P., Funk, A., Kondratieva, N., Leung, J., Van der Aa, L., Liu, W., Palmenberg, A.C., Hall, R.A. and Khromykh, A.A. (2008). Flaviviruses employ cellular mRNA decay machinery to generate subgenomic non-coding RNA required for pathogenicity. In: International Congress of Virology, Istanbul, Turkey, (). 10-15 Aug, 2008. 55  
Roby, Justin A., Funk, Anneke and Khromykh, Alexander A. (2012). Flavivirus replication and assembly. In Pei-Yong Shi (Ed.), Molecular virology and control of flaviviruses (pp. 21-49) Norfolk, United Kingdom: Caister Academic Press. 288 13
Khromykh, A.A. (2008). Flavivirus replication and cellular RNA decay machinery. In: 3rd AREVA-Pasteur Forum "Mosquito- and tick-borne viruses and their environment, Shanghai, China, (). 12-14 June, 2008. 65  
Khromykh, A (2006). Flavivirus replication and virus-host interactions. In: Annual Scientific Meeting & Exhibition - Aust Society for Microbiology. Annual Scientific Meeting & Exhibition - Aust Society for Micr, Gold Coast, (Abstract). 2-6 July, 2006. 90  
Funk, A., Torres, S., Edmonds, J., Pijlman, G., Hall, R., Lobigs, M., Kumagai, Y., Takeuchi, O., Akira, S. and Khromykh, A. (2009). Flavivirus subgenomic non-coding RNA is required to overcome the host innate immune response. In: 5th Australian Virology Group Meeting, Lorne, Australia, (). 13-17 December 2009. 157  
Pijlman, G.P., Funk, A., Kondratieva, N., Leung, J., Van der Aa, L., Liu, W., Palmenberg, , A.C., Hall, R.A. and Khromykh, A. (2008). Flavivirus subgenomic RNA generated by the mRNA decay machinery supports efficient virus replication. In: American Society for Virology Annual Meeting, Ithaca, USA, (). 12-16 July, 2008. 116  
Clarke, B. D., Roby, J. A., Slonchak, A. and Khromykh, A. A. (2015) Functional non-coding RNAs derived from the flavivirus 3' untranslated region.. Virus Research, . doi:10.1016/j.virusres.2015.01.026 11   Cited 0 times in Scopus0 1
Funk, Anneke and Khromykh, Alexander (2009) Generating flavivirus vaccine candidates by modulating interferon sensitivity. Expert Review of Vaccines, 8 9: 1157-1160. doi:10.1586/ERV.09.73 49   0 Cited 0 times in Scopus0 0
Ward, Scott M., Tindle, Robert W., Khromykh, Alexander A. and Gowans, Eric J. (2003) Generation of CTL responses using Kunjin replicon RNA. Immunology And Cell Biology, 81 1: 73-78. doi:10.1046/j.0818-9641.2002.01137.x 64   4 Cited 4 times in Scopus4 0
Clark, D. C., Khromykh, A. A., Mackenzie, J. S. and Hall, R. A. (2001). Identification of a region of the flavivirus nonstructural protein 1 (NS1) involved in dimerization. In: 1st Australian Virology Group Meeting. 1st Australian Virology Group Meeting, Fraser Island, (P1.39-P1.39). December, 2001. 61  
Setoh, Y. X., Prow, N. A., Hobson-Peters, J., Lobigs, M., Young, P. R., Khromykh, A. A. and Hall, R. A. (2012) Identification of residues in West Nile virus premembrane protein that influence viral particle secretion and virulence. Journal of General Virology, 93 Part 9: 1965-1975. doi:10.1099/vir.0.044453-0 65   2 Cited 1 times in Scopus1 0
Liu, Wen Jun, Wang, Xiang Ju, Mokhonov, Vladislav V., Shi, Pei-Yong, Randall, Richard and Khromykh, Alexander A. (2005) Inhibition of interferon signaling by the New York 99 strain and Kunjin subtype of West Nile virus involves blockage of STAT1 and STAT2 activation by nonstructural proteins. Journal of Virology, 79 3: 1934-1942. doi:10.1128/JVI.79.3.1934-1942.2005 58   154 Cited 153 times in Scopus153 0
Mackenzie, J M, Liu, W, Parton, R G and Khromykh, A (2006). Inhibition of interferon signaling in flavivirus-infected cells is associated with virus-induced cholesterol re-distribution. In: 13th International Mtg on Hepatitis C Virus & Related Viruses. 13th International Mtg on Hepatitis C Virus & Related Viruses, Cairns, (Abstract). 27-31 Aug, 2006. 51  
Rudd, Penny A., Wilson, Jane, Gardner, Joy, Larcher, Thibaut, Babarit, Candice, Le, Thuy T., Anraku, Itaru, Kumagai, Yutaro, Loo, Yueh-Ming, Gale Jr, Michael, Akira, Shizuo, Khromykh, Alexander A. and Suhrbier, Andreas (2012) Interferon response factors 3 and 7 protect against Chikungunya virus hemorrhagic fever and shock. Journal of Virology, 86 18: 9888-9898. doi:10.1128/JVI.00956-12 72   26 Cited 25 times in Scopus25 4
Frese, Michael, Lee, Eva, Larena, Maximilian, Lim, Pek Siew, Rao, Sudha, Matthaei, Klaus I., Khromykh, Alexander, Ramshaw, Ian and Lobigs, Mario (2014) Internal ribosome entry site-based attenuation of a flavivirus candidate vaccine and evaluation of the effect of beta interferon coexpression on vaccine properties. Journal of Virology, 88 4: 2056-2070. doi:10.1128/JVI.03051-13 147   1 Cited 1 times in Scopus1 0
Cartwright, L., Hall, R. A., Khromykh, A. A., Mackenzie, J. S. and Poidinger, M. (1999). Investigation of the structure and function of the flavivirus non-coding regions. In: Abstract Book, 11th International Congress of Virology. 11th International Congress of Virology, Sydney, (251). 9-13 August 1999. 30  

Page 1 of 3

Result Pages:    1 2 3  next › last »