Browse by all authors Browse By Author Name - Sobey,+Christopher+G.

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Thundyil, John, Pavlovski, Dale, Sobey, Christopher G. and Arumugam, Thiruma V. (2012) Adiponectin receptor signalling in the brain. British Journal of Pharmacology, 165 2: 313-327. doi:10.1111/j.1476-5381.2011.01560.x 81   26 Cited 33 times in Scopus33 0
Dinh, Quynh N., Arumugam, Thiruma V., Young, Morag J., Drummond, Grant R., Sobey, Christopher G. and Chrissobolis, Sophocles (2012) Aldosterone and the mineralocorticoid receptor in the cerebral circulation and stroke. Experimental and Translational Stroke Medicine, 4 1: 21.1-21.7. doi:10.1186/2040-7378-4-21 47 1 Cited 1 times in Scopus1 0
Broughton, Brad R. S., Reutens, David C. and Sobey, Christopher G. (2009) Apoptotic mechanisms after cerebral ischemia. Stroke, 40 5: e331-e339. doi:10.1161/STROKEAHA.108.531632 72   251 Cited 301 times in Scopus301 1
Park, Jong-Sung, Manzanero, Silvia, Chang, Jae-Woong, Choi, Yuri, Baik, Sang-Ha, Cheng, Yi-Lin, Li, Yu-I, Gwon, A-Ryeong, Woo, Ha-Na, Jang, Jiyeon, Choi, In-Young, Lee, Joo-Yong, Jung, Yong-Keun, Tang, Sung-Chun, Sobey, Christopher G., Arumugam, Thiruma V. and Jo, Dong-Gyu (2013) Calsenilin contributes to neuronal cell death in ischemic stroke. Brain Pathology, 23 4: 402-412. doi:10.1111/bpa.12013 60   1 Cited 1 times in Scopus1 0
Paravicini, Tamara M. and Sobey, Christopher G. (2003). Cerebral vascular effects of reactive oxygen species: Recent evidence for a role of NADPH-oxidase. In: Clinical and Experimental Pharmacology and Physiology. 36th Annual Scientific Meeting of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists, Melbourne, Australia, (855-859). 25–29 November 2002. doi:10.1046/j.1440-1681.2003.03920.x 36   27 Cited 30 times in Scopus30 0
Tang, Sung-Chun, Yeh, Shin-Joe, Li, Yu-I, Wang Yu-Chi, Baik, Sang-Ha, Santro, Tomislav, Widiapradja, Alexander, Manzanero, Silvia, Sobey, Christopher G., Jo, Dong-Gyu, Arumugam, Thiruma V. and Jeng, Jiann-Shing (2013) Evidence for a detrimental role of TLR8 in ischemic stroke. Experimental Neurology, 250 341-347. doi:10.1016/j.expneurol.2013.10.012 19   4 Cited 4 times in Scopus4 6
Cheng, Yi-Lin, Park, Jong-Sung, Manzanero, Silvia, Choi, Yuri, Baik, Sang-Ha, Okun, Eitan, Gelderblom, Mathias, Fann, David Yang-Wei, Magnus, Tim, Launikonis, Bradley S., Mattson, Mark P., Sobey, Christopher G., Jo, Dong-Gyu and Arumugam, Thiruma V. (2014) Evidence that collaboration between HIF-1alpha and Notch-1 promotes neuronal cell death in ischemic stroke. Neurobiology of Disease, 62 286-295. doi:10.1016/j.nbd.2013.10.009 43   3 Cited 2 times in Scopus2 0
Arumugam, Thiruma V., Cheng, Yi-Lin, Choi, Yuri, Choi, Yun-Hyung, Yang, Sunghee, Yun, Young-Kwang, Park, Jong-Sung, Yang, Dong Kwon, Thundyil, John, Gelderblom, Mathias, Karamyan, Vardan T., Tang, Sung-Chun, Chan, Sic L., Magnus, Tim, Sobey, Christopher G. and Jo, Dong-Gyu (2011) Evidence that {gamma}-Secretase-mediated Notch signaling induces neuronal cell death via the nuclear factor-{kappa}B-Bcl-2-interacting mediator of cell death pathway in ischemic stroke. Molecular Pharmacology, 80 1: 23-31. doi:10.1124/mol.111.071076 39   17 Cited 18 times in Scopus18 0
Cheng, Yi-Lin, Choi, Yuri, Seow, Wei Lun, Manzanero, Silvia, Sobey, Christopher G., Jo, Dong-Gyu and Arumugam, Thiruma V. (2014) Evidence that neuronal Notch-1 promotes JNK/c-Jun activation and cell death following ischemic stress. Brain Research, 1586 193-202. doi:10.1016/j.brainres.2014.08.054 18   0 Cited 0 times in Scopus0 1
Thundyil, John, Manzanero, Silvia, Pavlovski, Dale, Cully, Tanya R., Lok, Ker-Zhing, Widiapradja, Alexander, Chunduri, Prasad, Jo, Dong-Gyu, Naruse, Chie, Asano, Masahide, Launikonis, Bradley S., Sobey, Christopher G., Coulthard, Mark G. and Arumugam, Thiruma V. (2013) Evidence that the EphA2 receptor exacerbates ischemic brain injury. PLoS One, 8 1: e53528.1-e53528.8. doi:10.1371/journal.pone.0053528 80   4 Cited 6 times in Scopus6 2
Paravicini, Tamara M., Miller, Alyson A., Drummond, Grant R. and Sobey, Christopher G. (2006) Flow-induced cerebral vasodilatation in vivo involves activation of phosphatidylinositol-3 kinase, NADPH-oxidase, and nitric oxide synthase. Journal of Cerebral Blood Flow and Metabolism, 26 6: 836-845. doi:10.1038/sj.jcbfm.9600235 35   39 Cited 42 times in Scopus42 0
Chu, Hannah X., Kim, Hyun A., Lee, Seyoung, Moore, Jeffrey P., Chan, Christopher T., Vinh, Antony, Gelderblom, Mathias, Arumugam, Thiruma V., Broughton, Brad R. S., Drummond, Grant R. and Sobey, Christopher G. (2014) Immune cell infiltration in malignant middle cerebral artery infarction: comparison with transient cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism, 34 3: 450-459. doi:10.1038/jcbfm.2013.217 9   4 Cited 4 times in Scopus4 0
Brait, Vanessa H., Arumugam, Thiruma V., Drummond, Grant R. and Sobey, Christopher G. (2012) Importance of T lymphocytes in brain injury, immunodeficiency, and recovery after cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism, 32 4: 598-611. doi:10.1038/jcbfm.2012.6 26   40 Cited 42 times in Scopus42 0
Paravicini, Tamara M., Chrissobolis, Sophocles, Drummond, Grant R. and Sobey, Christopher G. (2004) Increased NADPH-oxidase activity and Nox4 expression during chronic hypertension is associated with enhanced cerebral vasodilatation to NADPH in vivo. Stroke, 35 2: 584-589. doi:10.1161/01.STR.0000112974.37028.58 32   85 Cited 89 times in Scopus89 0
Widiapradja, Alexander, Santro, Tomislav, Basta, Milan, Sobey, Christopher G., Manzanero, Silvia and Arumugam, Thiruma V. (2014) Intravenous immunoglobulin (IVIg) provides protection against endothelial cell dysfunction and death in ischemic stroke. Experimental and Translational Stroke Medicine, 6 1: . doi:10.1186/2040-7378-6-7 27 3 Cited 1 times in Scopus1 0
Widiapradja, Alexander, Vegh, Viktor, Lok, Ker Zhing, Manzanero, Silvia, Thundyil, John, Gelderblom, Mathias, Cheng, Yi-Lin, Pavlovski, Dale, Tang, Sung-Chun, Jo, Dong-Gyu, Magnus, Tim, Chan, Sic L., Sobey, Christopher G., Reutens, David, Basta, Milan, Mattson, Mark P. and Arumugam, Thiruma V. (2012) Intravenous immunoglobulin protects neurons against amyloid beta-peptide toxicity and ischemic stroke by attenuating multiple cell death pathways. Journal of Neurochemistry, 122 2: 321-332. doi:10.1111/j.1471-4159.2012.07754.x 89   12 Cited 12 times in Scopus12 2
Lee, Seyoung, Brait, Vanessa H., Arumugam, Thiruma V., Evans, Megan A., Kim, Hyun Ah, Widdop, Robert E., Drummond, Grant R., Sobey, Christopher G. and Jones, Emma S. (2012) Neuroprotective effect of an angiotensin receptor type 2 agonist following cerebral ischemia in vitro and in vivo. Experimental and Translational Stroke Medicine, 4 16: . doi:10.1186/2040-7378-4-16 55   Cited 6 times in Scopus6 0
Brait, Vanessa H., Martin, Katherine R., Corlett, Alicia, Broughton, Brad R. S., Kim, Hyun Ah, Thundyil, John, Drummond, Grant R., Arumugam, Thiruma V., Pritchard, Melanie A. and Sobey, Christopher G. (2012) Over-expression of DSCR1 protects against post-ischemic neuronal injury. PLoS One, 7 10: e47841.1-e47841.8. doi:10.1371/journal.pone.0047841 43   1 Cited 2 times in Scopus2 0
Fann, David Yang-Wei, Lee, Seung-Yoon, Manzanero, Silvia, Chunduri, Prasad, Sobey, Christopher G. and Arumugam, Thiruma V. (2013) Pathogenesis of acute stroke and the role of inflammasomes. Ageing Research Reviews, 12 4: 941-966. doi:10.1016/j.arr.2013.09.004 58   8 Cited 8 times in Scopus8 0
Woodruff, Trent M., Thundyil, John, Tang, Sung Chun, Sobey, Christopher G., Taylor, Stephen M. and Arumugam, Thiruma V. (2011) Pathophysiology, treatment, and animal and cellular models of human ischemic stroke. Molecular Neurodegeneration, 6 1: 1-19. doi:10.1186/1750-1326-6-11 119   52 Cited 65 times in Scopus65 0
Low, Pei Ching, Manzanero, Silvia, Mohannak, Nika, Narayana, Vinod K., Nguyen, Tam H., Kvaskoff, David, Brennan, Faith H., Ruitenberg, Marc J., Gelderblom, Mathias, Magnus, Tim, Kim, Hyun Ah, Broughton, Brad R. S., Sobey, Christopher G., Vanhaesebroeck, Bart, Stow, Jennifer L., Arumugam, Thiruma V. and Meunier, Frédéric A. (2014) PI3K delta inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model. Nature Communications, 5 3450: 1-12. doi:10.1038/ncomms4450 46   3 16
Baik, Sang-Ha, Fane, Mitchell, Park, Joon Hyung, Cheng, Yi-Lin, Fann, David Yang-Wei, Yun, Ui Jeong, Choi, Yuri, Park, Jong-Sung, Chai, Bing Han, Park, Jin Su, Back, Seung Hyun, Jeong, Jae In, Jang, Ye Jin, Bahn, Gahee, Lee, JooYong, Li, Yu-I, Sobey, Christopher G., Uchida, Takafumi, Park, Jae Hyung, Kim, Hong Tae, Tang, Sung-Chun, Arumugam, Thiruma V. and Jo, Dong-Gyu (2015) Pin1 promotes neuronal death in stroke by stabilizing notch intracellular domain.. Annals of Neurology, . doi:10.1002/ana.24347. 8   0
Broughton, Brad R., Lim, Rebecca, Arumugam, Thiruma V., Drummond, Grant R., Wallace, Euan M. and Sobey, Christopher G. (2013) Post-stroke inflammation and the potential efficacy of novel stem cell therapies: focus on amnion epithelial cells. Frontiers in Cellular Neuroscience, 6 DEC: 66.1-66.9. doi:10.3389/fncel.2012.00066 41 1 7 Cited 5 times in Scopus5 4
Paravicini, Tamara M., Drummond, Grant R. and Sobey, Christopher G. (2004) Reactive oxygen species in the cerebral circulation: Physiological roles and therapeutic implications for hypertension and stroke. Drugs, 64 19: 2143-2157. doi:10.2165/00003495-200464190-00001 31   23 Cited 23 times in Scopus23 0
Broughton, Brad R.S., Brait, Vanessa H., Ah Kim, Hyun, Lee, Seyoung, Chu, Hannah X., Gardiner-Mann, Chantelle V., Guida, Elizabeth, Evans, Megan A., Miller, Alyson A., Arumugam, Thiruma V., Drummond, Grant R. and Sobey, Christopher G. (2014) Sex-dependent effects of g protein-coupled estrogen receptor activity on outcome after ischemic stroke. Stroke, 45 3: 835-841. doi:10.1161/STROKEAHA.113.001499 24   1 Cited 1 times in Scopus1 2
Broughton, Brad R.S., Brait, Vanessa H., Guida, Elizabeth, Lee, Seyoung, Arumugam, Thiruma V., Gardiner-Mann, Chantelle V., Miller, Alyson A., Tang, Sung-Chun, Drummond, Grant R. and Sobey, Christopher G. (2013) Stroke increases G protein-coupled estrogen receptor expression in the brain of male but not female mice. NeuroSignals, 21 3-4: 229-239. doi:10.1159/000338019 47   2 Cited 3 times in Scopus3 0
Kim, Hyun Ah, Miller, Alyson A., Drummond, Grant R., Thrift, Amanda G., Arumugam, Thiruma V., Phan, Thanh G., Srikanth, Velandai K. and Sobey, Christopher G. (2012) Vascular cognitive impairment and Alzheimer's disease: role of cerebral hypoperfusion and oxidative stress. Naunyn-Schmiedeberg's Archives of Pharmacology, 385 10: 953-959. doi:10.1007/s00210-012-0790-7 35   12 Cited 12 times in Scopus12 0