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Trenholme, Katharine R., Brown, Christopher L., Skinner-Adams, Tina S., Stack, Colin, Lowther, Jonathan, To, Joyce, Robinson, Mark W., Donnelly, Sheila M., Dalton, John P. and Gardiner, Donald L. (2010) Aminopeptidases of malaria parasites: new targets for chemotherapy. Infectious Disorders - Drug Targets, 10 3: 217-225. doi:10.2174/187152610791163363 13   Cited 10 times in Scopus10 0
Hawthorne, Paula L., Trenholme, Katharine R., Skinner-Adams, Tina S., Spielmann, Tobias, Fischer, Katja, Dixon, Matthew W. A., Ortega, Maria R., Anderson, Karen L., Kemp, David J. and Gardiner, Donald L. (2004) A novel Plasmodium falciparum ring stage protein, REX, is located in Maurer's clefts. Molecular and Biochemical Parasitology, 136 2: 181-189. doi:10.1016/j.molbiopara.2004.03.013 117   54 Cited 50 times in Scopus50 0
Thivierge, Karine, Mathew, Rency T., Nsangou, Desire M. M., Da Silva, Fabio, Cotton, Sophie, Skinner-Adams, Tina S., Trenholme, Katharine R., Brown, Christopher L., Stack, Colin M., Gardiner, Donald L. and Dalton, John P. (2012) Anti-malaria drug development targeting the M1 alanyl and M17 leucyl aminopeptidases. Arkivoc, 2012 4: 330-346. doi:10.3998/ark.5550190.0013.424 15   1 Cited 1 times in Scopus1 0
Sumanadasa, Subathdrage D. M., Goodman, Christopher D., Lucke, Andrew J., Skinner-Adams, Tina, Sahama, Ishani, Haque, Ashraful, Do, Tram Anh, McFadden, Geoffrey I., Fairlie, David P. and Andrews, Katherine T. (2012) Antimalarial activity of the anticancer histone deacetylase inhibitor SB939. Antimicrobial Agents and Chemotherapy, 56 7: 3849-3856. doi:10.1128/AAC.00030-12 63   15 Cited 15 times in Scopus15 0
Peatey, Christopher L., Andrews, Katherine T., Eickel, Nina, MacDonald, Timothy, Butterworth, Alice S., Trenholme, Katharine R., Gardiner, Donald L., McCarthy, James S. and Skinner-Adams, Tina S. (2010) Antimalarial asexual stage-specific and gametocytocidal activities of HIV protease inhibitors. Antimicrobial Agents and Chemotherapy, 54 3: 1334-1337. doi:10.1128/AAC.01512-09 86   12 Cited 21 times in Scopus21 0
Skinner-Adams, Tina S., McCarthy, James S., Gardiner, Donald L., Hilton, Petrina M. and Andrews, Katherine T. (2004) Antiretrovirals as antimalarial agents. Journal of Infectious Diseases, 190 11: 1998-2000. doi:10.1086/425584 108   76 Cited 83 times in Scopus83 1
Skinner-Adams, Tina S., Guddat, Luke W., Gardiner, Donald L., McCarthy, James S. and Andrews, Katherine T. (2005) Aspartic proteases of Plasmodium falciparum as the target of HIV-1 protease inhibitors - Reply. Journal of Infectious Diseases, 191 8: 1382-1383. doi:10.1086/428782 103   3 Cited 12 times in Scopus12 0
Stack, Colin M., Lowther, Jonathan, Cunningham, Eithne, Donnelly, Sheila, Gardiner, Donald L., Trenholme, Katharine R., Skinner-Adams, Tina S., Teuscher, Franka, Grembecka, Jolanta, Mucha, Artur, Kafarski, Pawel, Lua, Linda, Bell, Angus and Dalton, John P. (2007) Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase. A protease involved in amino acid regulation with potential for antimalarial drug development. Journal of Biological Chemistry, 282 3: 2069-2080. doi:10.1074/jbc.M609251200 93   51 Cited 48 times in Scopus48 0
Gardiner, Donald L., Spielmann, Tobias, Dixon, Matthew W. A., Hawthorne, Paula L., Ortega, Maria R., Anderson, Karen L., Skinner-Adams, Tina S., Kemp, David J. and Trenholme, Katharine R. (2004) CLAG 9 is located in the rhoptries of Plasmodium falciparum. Parasitology Research, 93 1: 64-67. doi:10.1007/s00436-004-1098-4 86   0 Cited 16 times in Scopus16 0
Skinner-Adams, Tina S., Lawrie, Paula M., Hawthorne, Paula L., Gardiner, Donald L. and Trenholme, Katharine R. (2003) Comparison of Plasmodium falciparum transfection methods. Malaria Journal, 2 19.1-19.4. doi:10.1186/1475-2875-2-19 101   6 Cited 6 times in Scopus6 0
Peatey, Christopher L., Skinner-Adams, Tina S., Dixon, Matthew W. A., McCarthy, James S., Gardiner, Donald L. and Trenholme, Katharine R. (2009) Effect of Antimalarial Drugs on Plasmodium falciparum Gametocytes. The Journal of Infectious Diseases, 200 10: 1518-1521. doi:10.1086/644645 59   31 Cited 35 times in Scopus35 0
Poreba, Marcin, McGowan, Sheena, Skinner-Adams, Tina S., Trenholme, Katharine R., Gardiner, Donald L., Whisstock, James C., To, Joyce, Salvesen, Guy S., Dalton, John P. and Drag, Marcin (2012) Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum. Plos One, 7 2: e31938-1-e31938-8. doi:10.1371/journal.pone.0031938 85   10 Cited 15 times in Scopus15 0
Skinner-Adams, Tina S., Hawthorne, Paula L., Trenholme, Katharine R. and Gardiner, Donald L. (2003) GATEWAY™ vectors for Plasmodium falciparum transfection. Trends in Parasitology, 19 1: 17-18. doi:10.1016/S1471-4922(02)00005-3 77   12 Cited 8 times in Scopus8 0
Porter, Kimberly A., Cole, Stephen R., Eron, Joseph J., Jr., Zheng, Yu, Hughes, Michael D., Lockman, Shahin, Poole, Charles, Skinner-Adams, Tina S., Hosseinipour, Mina, Shaffer, Doug, D'Amico, Ronald, Sawe, Frederick K., Siika, Abraham, Stringer, Elizabeth, Currier, Judith S., Chipato, Tsungai, Salata, Robert, McCarthy, James S. and Meshnicka, Steven R. (2012) HIV-1 protease inhibitors and clinical malaria: A secondary analysis of the AIDS Clinical Trials Group A5208 study. Antimicrobial Agents and Chemotherapy, 56 2: 995-1000. doi:10.1128/AAC.05322-11 40   4 Cited 4 times in Scopus4 1
Skinner-Adams, Tina S., Lowther, Jonathan, Teuscher, Franka, Stack, Colin M., Grembecka, Jolanta, Mucha, Artur, Kafarski, Pawel, Trenholme, Katharine R., Dalton, John P. and Gardiner, Donald L. (2007) Identification of phosphinate dipeptide analog inhibitors directed against the Plasmodium falciparum M17 leucine aminopeptidase as lead antimalarial compounds. Journal of Medicinal Chemistry, 50 24: 6024-6031. doi:10.1021/jm070733v 45   39 Cited 38 times in Scopus38 0
Gardiner, Donald L., Dixon, Matthew W. A., Spielmann, Tobias, Skinner-Adams, Tina S., Hawthorne, Paula L., Ortega, Maria R., Kemp, David J. and Trenholme, Katharine R. (2005) Implication of a Plasmodium falciparum gene in the switch between asexual reproduction and gametocytogenesis. Molecular and Biochemical Parasitology, 140 2: 153-160. doi:10.1016/j.molbiopara.2004.12.010 86   21 Cited 22 times in Scopus22 0
Keough, Dianne T., Hockova, Dana, Holy, Antonin, Naesens, Lieve M. J., Skinner-Adams, Tina S., de Jersey, John and Guddat, Luke W. (2009) Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: A new class of antimalarial therapeutics. Journal of Medicinal Chemistry, 52 14: 4391-4399. doi:10.1021/jm900267n 76   35 Cited 34 times in Scopus34 0
Keough, Dianne T., Skinner-Adams, Tina, Jones, Malcolm K., Ng, Ai-Lin., Brereton, Ian M., Guddat, Luke W. and de Jersey, John (2006) Lead compounds for antimalarial chemotherapy: Purine base analogs discriminate between human and P-falciparum 6-oxopurine phosphoribosyltransferases. Journal of Medicinal Chemistry, 49 25: 7479-7486. doi:10.1021/jm061012j 135   30 Cited 26 times in Scopus26 0
Trenholme, Katharine, Marek, Linda, Duffy, Sandra, Pradel, Gabriele, Fisher, Gillian, Hansen, Finn K., Skinner-Adams, Tina S., Butterworth, Alice, Ngwa, Che Julius, Moecking, Jonas, Goodman, Christopher D., McFadden, Geoffrey I., Sumanadasa, Subathdrage D. M., Fairlie, David P., Avery, Vicky M., Kurz, Thomas and Andrews, Katherine T. (2014) Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules. Antimicrobial Agents and Chemotherapy, 58 7: 3666-3678. doi:10.1128/AAC.02721-13 17   2 Cited 2 times in Scopus2 4
Gardiner, Donald L., Skinner-Adams, Tina S., Spielmann, Tobias and Trenholme, Katharine R. (2003) Malaria transfection and transfection vectors. Trends In Parasitology, 19 9: 381-383. doi:10.1016/S1471-4922(03)00187-9 66   19 Cited 21 times in Scopus21 0
Raju, Ritesh, Khalil, Zeinab G., Piggott, Andrew M., Blumenthal, Antje, Gardiner, Donald L., Skinner-Adams, Tina S. and Capon, Robert J. (2014) Mollemycin A: an antimalarial and antibacterial glyco-hexadepsipeptide-polyketide from an Australian marine-derived Streptomyces sp. (CMB-M0244). Organic Letters, 16 6: 1716-1719. doi:10.1021/ol5003913 29   1 Cited 1 times in Scopus1 1
Gardiner, Donald L., Trenholme, Katharine R., Skinner-Adams, Tina S., Stack, Colin M. and Dalton, John P. (2006) Overexpression of Leucyl Aminopeptidase in Plasmodium falciparum Parasites. Target for the antimalarial activity of bestatin. Journal of Biological Chemistry, 281 3: 1741-1745. doi:10.1074/jbc.M508955200 53   42 Cited 41 times in Scopus41 1
Butterworth, Alice S., Skinner-Adams, Tina S., Gardiner, Don L. and Trenholme, Katharine R. (2013) Plasmodium falciparum gametocytes: With a view to a kill. Parasitology, 140 14: 1718-1734. doi:10.1017/S0031182013001236 29   3 Cited 3 times in Scopus3 2
Andrews, Kathy T., Tran, Thanh N., Lucke, Andrew, Kahnberg, Pia, Lee, G. T., Skinner-Adams, Tina, Gardiner, Donald L. and Fairlie, David P. (2007). Plasmodium falciparum histone deacetylases: Enzymes involved in gene regulation as new antimalarial drug targets. In: Abstract Book: American Society of Tropical Medicine and Hygiene : 56th Annual Meeting. 56th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene, Philadelphia, PA United States, (48-48). 04-08 November 2007. 22   0
Gardiner, Donald L., Skinner-Adams, Tina S., Brown, Christopher L., Andrews, Katherine T., Stack, Colin M., McCarthy, James S., Dalton, John P. and Trenholme, Katharine R. (2009) Plasmodium falciparum: New molecular targets with potential for antimalarial drug development. Expert Review of Anti-Infective Therapy, 7 9: 1087-1098. doi:10.1586/ERI.09.93 55   10 Cited 13 times in Scopus13 0
Vu, Hoan, Roullier, Catherine, Campitelli, Marc, Trenholme, Katharine R., Gardiner, Donald L., Andrews, Katherine T., Skinner-Adams, Tina, Crowther, Gregory J., Van Voorhis, Wesley C. and Quinn, Ronald J. (2013) Plasmodium gametocyte inhibition identified from a natural-product-based fragment library. ACS Chemical Biology, 8 12: 2654-2659. doi:10.1021/cb400582b 26   2 Cited 2 times in Scopus2 11
Andrews, Katherine T., Fairlie, David P., Madala, Praveen K., Ray, John, Wyatt, David M., Hilton, Petrina M., Melville, Lewis A., Beattie, Lynette, Gardiner, Donald L., Reid, Robert C., Stoermer, Martin J., Skinner-Adams, Tina, Berry, Colin and McCarthy, James S. (2006) Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria. Antimicrobial Agents And Chemotherapy, 50 2: 639-648. doi:10.1128/AAC.50.2.639-648.2006 102   77 Cited 82 times in Scopus82 1
Mudianta, I. Wayan, Skinner-Adams, Tina, Andrews, Katherine T., Davis, Rohan A., Hadi, Tri A., Hayes, Patricia Y. and Garson, Mary J. (2012) Psammaplysin derivatives from the Balinese marine sponge Aplysinella strongylata. Journal of Natural Products, 75 12: 2132-2143. doi:10.1021/np300560b 45   4 Cited 4 times in Scopus4 0
Martin, Rowena E., Butterworth, Alice S., Gardiner, Donald L., Kirk, Kiaran, McCarthy, James S. and Skinner-Adams, Tina S. (2012) Saquinavir Inhibits the malaria parasite's chloroquine resistance transporter. Antimicrobial Agents and Chemotherapy, 56 5: 2283-2289. doi:10.1128/AAC.00166-12 43   11 Cited 12 times in Scopus12 0
McGowan, Sheena, Porter, Corrine J., Lowther, Jonathan, Stack, Colin M., Golding, Sarah J., Skinner-Adams, Tina S., Trenholme, Katharine R., Teuscher, Franka, Donnelly, Sheila M., Grembecka, Jolanta, Mucha, Artur, Kafarski, Pawel, DeGori, Ross, Buckle, Ashley M., Gardiner, Donald L., Whisstock, James C. and Dalton, John P. (2009) Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase. Proceedings of the National Academy of Sciences of USA, 106 8: 2537-2542. doi:10.1073/pnas.0807398106 33   57 Cited 59 times in Scopus59 7
Skinner-Adams, Tina S., Peatey, Christopher L., Anderson, Karen, Trenholme, Katharine R., Krige, David, Brown, Christopher L., Stack, Colin, Nsangou, Desire M. M., Mathews, Rency T., Thivierge, Karine, Dalton, John P. and Gardinerd, Donald L. (2012) The aminopeptidase inhibitor CHR-2863 is an orally bioavailable inhibitor of murine malaria. Antimicrobial Agents and Chemotherapy, 56 6: 3244-3249. doi:10.1128/AAC.06245-11 40   6 Cited 6 times in Scopus6 1
Skinner-Adams,Tina S., Butterworth, Alice S., Porter, Kimberly A., D'Amico, Ronald, Sawe, Fred, Shaffer, Doug, Siika, Abraham, Hosseinipour, Mina C., Stringer, Elizabeth, Currier, Judith S., Chipato, Tsungai, Salata, Robert, Lockman, Shahin, Eron, Joseph J., Meshnick, Steven R. and McCarthy, James S. (2012) The frequency of malaria is similar among women receiving either lopinavir/ritonavir or nevirapine-based antiretroviral treatment. PLoS One, 7 4 Article No. e34399: e34399-1-e34399-4. doi:10.1371/journal.pone.0034399 22   3 Cited 2 times in Scopus2 1