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Trenholme, Katharine R., Brown, Christopher L., Skinner-Adams, Tina S., Stack, Colin, Lowther, Jonathan, To, Joyce, Robinson, Mark W., Donnelly, Sheila M., Dalton, John P. and Gardiner, Donald L. (2010) Aminopeptidases of malaria parasites: new targets for chemotherapy. Infectious Disorders - Drug Targets, 10 3: 217-225. doi:10.2174/187152610791163363 14   Cited 11 times in Scopus11 0
Hawthorne, Paula L., Trenholme, Katharine R., Skinner-Adams, Tina S., Spielmann, Tobias, Fischer, Katja, Dixon, Matthew W. A., Ortega, Maria R., Anderson, Karen L., Kemp, David J. and Gardiner, Donald L. (2004) A novel Plasmodium falciparum ring stage protein, REX, is located in Maurer's clefts. Molecular and Biochemical Parasitology, 136 2: 181-189. doi:10.1016/j.molbiopara.2004.03.013 122   54 Cited 50 times in Scopus50 0
Thivierge, Karine, Mathew, Rency T., Nsangou, Desire M. M., Da Silva, Fabio, Cotton, Sophie, Skinner-Adams, Tina S., Trenholme, Katharine R., Brown, Christopher L., Stack, Colin M., Gardiner, Donald L. and Dalton, John P. (2012) Anti-malaria drug development targeting the M1 alanyl and M17 leucyl aminopeptidases. Arkivoc, 2012 4: 330-346. doi:10.3998/ark.5550190.0013.424 22   1 Cited 1 times in Scopus1 0
Peatey, Christopher L., Andrews, Katherine T., Eickel, Nina, MacDonald, Timothy, Butterworth, Alice S., Trenholme, Katharine R., Gardiner, Donald L., McCarthy, James S. and Skinner-Adams, Tina S. (2010) Antimalarial asexual stage-specific and gametocytocidal activities of HIV protease inhibitors. Antimicrobial Agents and Chemotherapy, 54 3: 1334-1337. doi:10.1128/AAC.01512-09 91   13 Cited 21 times in Scopus21 0
Skinner-Adams, Tina S., McCarthy, James S., Gardiner, Donald L., Hilton, Petrina M. and Andrews, Katherine T. (2004) Antiretrovirals as antimalarial agents. Journal of Infectious Diseases, 190 11: 1998-2000. doi:10.1086/425584 111   78 Cited 84 times in Scopus84 1
Skinner-Adams, Tina S., Guddat, Luke W., Gardiner, Donald L., McCarthy, James S. and Andrews, Katherine T. (2005) Aspartic proteases of Plasmodium falciparum as the target of HIV-1 protease inhibitors - Reply. Journal of Infectious Diseases, 191 8: 1382-1383. doi:10.1086/428782 105   3 Cited 12 times in Scopus12 0
Stack, Colin M., Lowther, Jonathan, Cunningham, Eithne, Donnelly, Sheila, Gardiner, Donald L., Trenholme, Katharine R., Skinner-Adams, Tina S., Teuscher, Franka, Grembecka, Jolanta, Mucha, Artur, Kafarski, Pawel, Lua, Linda, Bell, Angus and Dalton, John P. (2007) Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase. A protease involved in amino acid regulation with potential for antimalarial drug development. Journal of Biological Chemistry, 282 3: 2069-2080. doi:10.1074/jbc.M609251200 97   54 Cited 54 times in Scopus54 0
Gardiner, Donald L., Spielmann, Tobias, Dixon, Matthew W. A., Hawthorne, Paula L., Ortega, Maria R., Anderson, Karen L., Skinner-Adams, Tina S., Kemp, David J. and Trenholme, Katharine R. (2004) CLAG 9 is located in the rhoptries of Plasmodium falciparum. Parasitology Research, 93 1: 64-67. doi:10.1007/s00436-004-1098-4 88   0 Cited 17 times in Scopus17 0
Skinner-Adams, Tina S., Lawrie, Paula M., Hawthorne, Paula L., Gardiner, Donald L. and Trenholme, Katharine R. (2003) Comparison of Plasmodium falciparum transfection methods. Malaria Journal, 2 19.1-19.4. doi:10.1186/1475-2875-2-19 105   6 Cited 6 times in Scopus6 0
Peatey, Christopher L., Skinner-Adams, Tina S., Dixon, Matthew W. A., McCarthy, James S., Gardiner, Donald L. and Trenholme, Katharine R. (2009) Effect of Antimalarial Drugs on Plasmodium falciparum Gametocytes. The Journal of Infectious Diseases, 200 10: 1518-1521. doi:10.1086/644645 61   31 Cited 36 times in Scopus36 0
Poreba, Marcin, McGowan, Sheena, Skinner-Adams, Tina S., Trenholme, Katharine R., Gardiner, Donald L., Whisstock, James C., To, Joyce, Salvesen, Guy S., Dalton, John P. and Drag, Marcin (2012) Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum. Plos One, 7 2: e31938-1-e31938-8. doi:10.1371/journal.pone.0031938 97   11 Cited 18 times in Scopus18 0
Skinner-Adams, Tina S., Hawthorne, Paula L., Trenholme, Katharine R. and Gardiner, Donald L. (2003) GATEWAY™ vectors for Plasmodium falciparum transfection. Trends in Parasitology, 19 1: 17-18. doi:10.1016/S1471-4922(02)00005-3 80   12 Cited 8 times in Scopus8 0
Porter, Kimberly A., Cole, Stephen R., Eron, Joseph J., Jr., Zheng, Yu, Hughes, Michael D., Lockman, Shahin, Poole, Charles, Skinner-Adams, Tina S., Hosseinipour, Mina, Shaffer, Doug, D'Amico, Ronald, Sawe, Frederick K., Siika, Abraham, Stringer, Elizabeth, Currier, Judith S., Chipato, Tsungai, Salata, Robert, McCarthy, James S. and Meshnicka, Steven R. (2012) HIV-1 protease inhibitors and clinical malaria: A secondary analysis of the AIDS Clinical Trials Group A5208 study. Antimicrobial Agents and Chemotherapy, 56 2: 995-1000. doi:10.1128/AAC.05322-11 42   6 Cited 6 times in Scopus6 1
Skinner-Adams, Tina S., Lowther, Jonathan, Teuscher, Franka, Stack, Colin M., Grembecka, Jolanta, Mucha, Artur, Kafarski, Pawel, Trenholme, Katharine R., Dalton, John P. and Gardiner, Donald L. (2007) Identification of phosphinate dipeptide analog inhibitors directed against the Plasmodium falciparum M17 leucine aminopeptidase as lead antimalarial compounds. Journal of Medicinal Chemistry, 50 24: 6024-6031. doi:10.1021/jm070733v 48   42 Cited 42 times in Scopus42 0
Gardiner, Donald L., Dixon, Matthew W. A., Spielmann, Tobias, Skinner-Adams, Tina S., Hawthorne, Paula L., Ortega, Maria R., Kemp, David J. and Trenholme, Katharine R. (2005) Implication of a Plasmodium falciparum gene in the switch between asexual reproduction and gametocytogenesis. Molecular and Biochemical Parasitology, 140 2: 153-160. doi:10.1016/j.molbiopara.2004.12.010 96   21 Cited 22 times in Scopus22 0
Keough, Dianne T., Hockova, Dana, Holy, Antonin, Naesens, Lieve M. J., Skinner-Adams, Tina S., de Jersey, John and Guddat, Luke W. (2009) Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: A new class of antimalarial therapeutics. Journal of Medicinal Chemistry, 52 14: 4391-4399. doi:10.1021/jm900267n 77   36 Cited 37 times in Scopus37 0
Trenholme, Katharine, Marek, Linda, Duffy, Sandra, Pradel, Gabriele, Fisher, Gillian, Hansen, Finn K., Skinner-Adams, Tina S., Butterworth, Alice, Ngwa, Che Julius, Moecking, Jonas, Goodman, Christopher D., McFadden, Geoffrey I., Sumanadasa, Subathdrage D. M., Fairlie, David P., Avery, Vicky M., Kurz, Thomas and Andrews, Katherine T. (2014) Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules. Antimicrobial Agents and Chemotherapy, 58 7: 3666-3678. doi:10.1128/AAC.02721-13 20   3 Cited 3 times in Scopus3 4
Gardiner, Donald L., Skinner-Adams, Tina S., Spielmann, Tobias and Trenholme, Katharine R. (2003) Malaria transfection and transfection vectors. Trends In Parasitology, 19 9: 381-383. doi:10.1016/S1471-4922(03)00187-9 68   19 Cited 21 times in Scopus21 0
Raju, Ritesh, Khalil, Zeinab G., Piggott, Andrew M., Blumenthal, Antje, Gardiner, Donald L., Skinner-Adams, Tina S. and Capon, Robert J. (2014) Mollemycin A: an antimalarial and antibacterial glyco-hexadepsipeptide-polyketide from an Australian marine-derived Streptomyces sp. (CMB-M0244). Organic Letters, 16 6: 1716-1719. doi:10.1021/ol5003913 40   1 Cited 1 times in Scopus1 1
Gardiner, Donald L., Trenholme, Katharine R., Skinner-Adams, Tina S., Stack, Colin M. and Dalton, John P. (2006) Overexpression of Leucyl Aminopeptidase in Plasmodium falciparum Parasites. Target for the antimalarial activity of bestatin. Journal of Biological Chemistry, 281 3: 1741-1745. doi:10.1074/jbc.M508955200 56   42 Cited 42 times in Scopus42 1
Butterworth, Alice S., Skinner-Adams, Tina S., Gardiner, Don L. and Trenholme, Katharine R. (2013) Plasmodium falciparum gametocytes: With a view to a kill. Parasitology, 140 14: 1718-1734. doi:10.1017/S0031182013001236 31   3 Cited 3 times in Scopus3 2
Gardiner, Donald L., Skinner-Adams, Tina S., Brown, Christopher L., Andrews, Katherine T., Stack, Colin M., McCarthy, James S., Dalton, John P. and Trenholme, Katharine R. (2009) Plasmodium falciparum: New molecular targets with potential for antimalarial drug development. Expert Review of Anti-Infective Therapy, 7 9: 1087-1098. doi:10.1586/ERI.09.93 57   10 Cited 14 times in Scopus14 0
Martin, Rowena E., Butterworth, Alice S., Gardiner, Donald L., Kirk, Kiaran, McCarthy, James S. and Skinner-Adams, Tina S. (2012) Saquinavir Inhibits the malaria parasite's chloroquine resistance transporter. Antimicrobial Agents and Chemotherapy, 56 5: 2283-2289. doi:10.1128/AAC.00166-12 43   12 Cited 12 times in Scopus12 0
McGowan, Sheena, Porter, Corrine J., Lowther, Jonathan, Stack, Colin M., Golding, Sarah J., Skinner-Adams, Tina S., Trenholme, Katharine R., Teuscher, Franka, Donnelly, Sheila M., Grembecka, Jolanta, Mucha, Artur, Kafarski, Pawel, DeGori, Ross, Buckle, Ashley M., Gardiner, Donald L., Whisstock, James C. and Dalton, John P. (2009) Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase. Proceedings of the National Academy of Sciences of USA, 106 8: 2537-2542. doi:10.1073/pnas.0807398106 36   63 Cited 65 times in Scopus65 7
Skinner-Adams, Tina S., Peatey, Christopher L., Anderson, Karen, Trenholme, Katharine R., Krige, David, Brown, Christopher L., Stack, Colin, Nsangou, Desire M. M., Mathews, Rency T., Thivierge, Karine, Dalton, John P. and Gardinerd, Donald L. (2012) The aminopeptidase inhibitor CHR-2863 is an orally bioavailable inhibitor of murine malaria. Antimicrobial Agents and Chemotherapy, 56 6: 3244-3249. doi:10.1128/AAC.06245-11 41   9 Cited 10 times in Scopus10 1
Skinner-Adams,Tina S., Butterworth, Alice S., Porter, Kimberly A., D'Amico, Ronald, Sawe, Fred, Shaffer, Doug, Siika, Abraham, Hosseinipour, Mina C., Stringer, Elizabeth, Currier, Judith S., Chipato, Tsungai, Salata, Robert, Lockman, Shahin, Eron, Joseph J., Meshnick, Steven R. and McCarthy, James S. (2012) The frequency of malaria is similar among women receiving either lopinavir/ritonavir or nevirapine-based antiretroviral treatment. PLoS One, 7 4 Article No. e34399: e34399-1-e34399-4. doi:10.1371/journal.pone.0034399 22   5 Cited 4 times in Scopus4 1