Browse by all authors Browse By Author Name - Richardson,+D.+R.

Browse Results (35 results found)

Subscribe to the RSS feed for this result setSubscribe to the RSS feed for this result set

  Abstract Views File Downloads Thomson Reuters Web of Science Citation Count Scopus Citation Count Altmetric Score
Richardson, D. R., Chua, A. G. C. and Baker, E. (1999) Activation of an iron uptake mechanism from transferrin in hepatocytes by small-molecular-weight iron complexes: implications for the pathogenesis of iron-overload disease. Journal of Laboratory and Clinical Medicine, 133 2: 144-151. doi:10.1016/S0022-2143(99)90007-0 37   18 Cited 13 times in Scopus13 0
Bernhardt, P. V., Mattsson, J. and Richardson, D. R. (2006) Complexes of cytotoxic chelators from the dipyridyl ketone isonicotinoyl hydrazone (HPKIH) analogues. Inorganic Chemistry, 45 2: 752-760. doi:10.1021/ic051573l 115   46 Cited 47 times in Scopus47 0
Richardson, D. R. and Bernhardt, P. V. (1999) Crystal and molecular structure of 2-hydroxy-1-naphthaldehyde isonicotinoyl hydrazone (NIH) and its iron(III) complex: an iron chelator with anti-tumour activity. Journal of Biological Inorganic Chemistry, 4 3: 266-273. doi:10.1007/s007750050312 167   86 Cited 93 times in Scopus93 0
Bernhardt, P. V., Caldwell, L. M., Chaston, T. B., Chin, P. and Richardson, D. R. (2003) Cytotoxic iron chelators: Characterization of the structure, solution chemistry and redox activity of ligands and iron complexes of the di-2-pyridyl ketone isonicotinoyl hydrazone (HPKIH) analogues. Journal of Biological Inorganic Chemistry, 8 8: 866-880. doi:10.1007/s00775-003-0486-z 97   59 Cited 62 times in Scopus62 0
Kalinowski, D. S., Yu, Y., Sharpe, P. C., Islam, M., Liao, Y. T., Lovejoy, D. B., Kumar, N., Bernhardt, P. V. and Richardson, D. R. (2007) Design, synthesis, and characterization of novel iron chelators: Structure-activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3-nitrobenzoyl analogues as potent antitumor agents. Journal of Medicinal Chemistry, 50 15: 3716-3729. doi:10.1021/jm070445z 135   96 Cited 101 times in Scopus101 0
Becker, E. and Richardson, D. R. (1999). Development of novel aroylhydrazone iron chelators for the treatment of iron-loading diseases. In: World Congress on Iron Metabolism. Bioiron'99, Sorrento Palace, Sorrento-Naples, Italy, (384). 23-28 May, 1999. 36  
Richardson, D. R., Sharpe, P. C., Lovejoy, D. B., Senaratne, D., Kalinowski, D. S., Islam, M. and Bernhardt, P. V. (2006) Dipyridyl thiosemicarbazone chelators with potent and selective antitumor activity form iron complexes with redox activity. Journal of Medicinal Chemistry, 49 22: 6510-6521. doi:10.1021/jm0606342 143   153 Cited 153 times in Scopus153 0
Becker, E. M., Greer, J. M., Ponka, P. and Richardson, D. R. (2002) Erythroid differentiation and protoporphyrin IX down-regulate frataxin expression in Friend cells: characterization of frataxin expression compared to molecules involved in iron metabolism and hemoglobinization. Blood, 99 10: 3813-3822. doi:10.1182/blood.V99.10.3813 52   44 Cited 46 times in Scopus46 0
Watts, R. and Richardson, D. R. (2000) Examination of the mechanism of action of nitrogen monoxide on iron uptake from transferrin. Journal of Laboratory and Clinical Medicine, 136 2: 149-156. doi:10.1067/mlc.2000.108152 29   8 Cited 11 times in Scopus11 0
Bernhardt, P. V., Caldwell, L., Lovejoy, D. and Richardson, D. R. (2003) Four cytotoxic N4-substituted thiosemicarbazones derived from 2-hydroxynaphthalene-1-carboxaldehyde. Acta Crystallographica Section C: Crystal Structure Communications, 59 11: o629-o633. doi:10.1107/S0108270103021401 76   7 Cited 8 times in Scopus8 0
Becker, E. M., Lovejoy, D. B., Greer, J. M., Watts, R. and Richardson, D. R. (2003) Identification of the di-pyridyl ketone isonicotinoyl hydrazone (PKIH) analogues as potent iron chelators and anti-tumour agents. British Journal of Pharmacology, 138 5: 819-830. doi:10.1038/sj.bjp.0705089 66   62 Cited 63 times in Scopus63 0
Wardrop, S. L., Wells, C., Ravasi, T., Hume, D. A. and Richardson, D. R. (2002) Induction of Nramp2 in activated mouse macrophages is dissociated from regulation of the Nramp1, classical inflammatory genes, and genes involved in iron metabolism. Journal of Leukocyte Biology, 71 1: 99-106. 74   15 Cited 13 times in Scopus13
Wardrop, S. L. and Richardson, D. R. (2000) Interferon-γ and lipopolysaccharide regulate the expression of Nramp2 and increase the uptake of iron from low relative molecular mass complexes by macrophages. European Journal of Biochemistry, 267 22: 6586-6593. doi:10.1046/j.1432-1327.2000.01752.x 40   48 0
Wardrop, S. and Richardson, D. R. (1999). Interferon-g and lipopolysaccharide differentially regulate the expression of the iron transporter Nramp2 in macrophages. In: Combined Conference of the Aust. Society for Biochemistry & Molecular Biology, Aust. & New Zealand Society for Cell & Developmental Biology & Aust. Society of Plant Physiologists. BomBio99, Conrad Jupiter's, Gold Coast, Qld., (98). 27 - 30 Sept, 1999. 30  
Bernhardt, P. V., Chin, P. and Richardson, D. R. (2004) Iron catalysed assembly of an asymmetric mixed-ligand triple helicate. Dalton Transactions, 2004 20: 3342-3346. doi:10.1039/b408781j 60   18 Cited 10 times in Scopus10 0
Wardrop, S. and Richardson, D. R. (1999). Lipopolysaccaride and/or interferon-g regulate the expression of Nramp2, Nramp1 and the tranferrin receptor independently of the iron-regulatory protein in macrophages: A possible role of Nramp2 in host defence?. In: Proceedings of the International Conference on Oxidative Pathways in Health and Disease. Proceedings of the International Conference on Oxidative Pathways in Health and Disease, Veterinary Fac. Conference Cen., Univ. of Sydney, (). 1 - 4 Dec,1999. 47  
Wardrop, S. L., Watts, R. N. and Richardson, D. R. (2000) Nitrogen monoxide activates iron regulatory protein 1 RNA - binding activity by two possible mechanisms: effect on the [4Fe-4S] cluster and iron mobilization from cells. Biochemistry, 39 10: 2748-2758. doi:10.1021/bi991099t 60   52 Cited 54 times in Scopus54 0
Wardrop, S., Watts, R. N. and Richardson, D. R. (1999). Nitrogen monoxide (NO) activates IRP1-RNA binding by two possible mechanisms - a direct effect on the FES cluster and iron release from cells. In: World Congress on Iron Metabolism. Bioiron'99, Sorrento Palace, Sorrento - Naples, Italy, (131). 23 - 28 May 1999. 47  
Lovejoy, D. B., Kalinowski, D., Bernhardt, P. V. and Richardson, D. R. (2006) PCTH: A novel orally active chelator for the treatment of iron overload disease. Hemoglobin, 30 1: 93-104. doi:10.1080/03630260500455367 53   4 Cited 4 times in Scopus4 0
Richardson, D. R. (1999) Role of ceruloplasmin and ascorbate in cellular iron release. Journal of Laboratory and Clinical Medicine, 134 5: 454-465. doi:10.1016/S0022-2143(99)90166-X 34   43 Cited 41 times in Scopus41 0
Chua, A. C., Richardson, D. R. and Baker, E. (1999). Small MrFe complexes stimulate iron uptake by heptocytes from iron transferrin and iron citrate. In: World Congress on Iron Metabolism. Bioiron'99, Sorrento Palace, Sorrent-Naples, Italy, (358). 23-28 May 1999. 37  
Armstrong, C. M., Bernhardt, P. V., Chin, P. and Richardson, D. R. (2003) Structural variations and formation constants of first-row transition metal complexes of biologically active aroylhydrazones. European Journal of Inorganic Chemistry, 2003 6: 1145-1156. doi:10.1002/ejic.200390146 93   73 Cited 74 times in Scopus74 0
Richardson, D. R., Becker, E. and Bernhardt, P. V. (1999) The biologically active iron chelators 2-pyridylcarboxaldehyde isonicotinoylhydrozone, 2-pyridylcarboxaldehyde benzoylhydrazone monohydrate and 2-furaldehyde isonicotinoylhydrazone. Acta Crystallographica Section C-Crystal Structure Communications, 15 55 (Pt12): 2102-2105. 48  
Darnell, G. and Richardson, D. R. (1999). The effect of a novel iron chelator on molecular targets involved in cellular proliferation: the possible roles of WAF1 and GADD45 cycle arrest. In: World Congress on Iron Metabolism. Bioiron'99, Sorrento Palace, Sorrento-Naples, Italy, (19). 23-28 May 1999. 31  
Richardson, D. R. (1999). The effect of ceruloplasmin and other agents on iron uptake and release by HEPG2 cells. In: World Congress on Iron Metabolism. Bioiron'99, Sorrento Palace, Sorrento-Naples, Italy, (347). 23-28 May 1999. 25  
Wardrop, S. L. and Richardson, D. R. (1999) The effect of intracellular iron concentration and nitrogen monoxide on NRAMP2 expression and non-transferrin-bound iron uptake. European Journal of Biochemistry, 263 1: 41-49. doi:10.1046/j.1432-1327.1999.00447.x 46   67 Cited 65 times in Scopus65 0
Wardrop, S. and Richardson, D. R. (1999). The iron transporter Nramp2 is not regulated like the tranferrin receptor in LMTK-fibroblasts: The roles of non-iron responsive element (IRE) and the IRE-containing Nramp2 mRNA transcripts. In: Combined Conference of the Aust. Society for Biochemistry & Molecular Biology, Aust. & New Zealand Society for Cell & Developmental Biology & Aust. Society of Plant Physiologists. ComBio99, Conrad Jupiter's, Gold Coast, Qld., (81). 27 - 30 Sept, 1999. 47  
Wardrop, S., Watts, R. N. and Richardson, D. R. (1999). The mechanisms involved in nitrogen monoxide (NO) mediated iron-regulatory protein 1 (IRP1) activation and cellular iron mobilization. In: Combined Conference of the Aust. Society for Biochemistry & Molecular Biology, Aust. & New Zealand Society for Cell & Develpmental Biology & Aust. Society of Plant Physiologists. ComBio99, Conrad Jupiter's, Gold Coast, Qld., (87). 27 - 30 Sept,1999. 34  
Darnell, G. and Richardson, D. R. (1999) The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents III: the effect of the ligands on molecular targets involved in proliferation. Blood, 94 2: 781-792. 83   111
Richardson, D. R. (1999). The role of melanotransferrin (tumour antigen p97) in iron uptake by the human malignant melanoma cell. In: World Congress on Iron Metabolism. Bioiron'99, Sorrento Palace, Sorrento-Naples, Italy, (289). 23-28 May 1999. 18  
Richardson, D. R. (2000) The role of the membrane-bound tumour antigen, melanotransferrin (p97), in iron uptake by the human mailignant melanoma cell.. European Journal of Biochemistry, 267 5: 1290-1298. doi:10.1046/j.1432-1327.2000.01079.x 38   46 Cited 47 times in Scopus47 3
Richardson, D. R. (1999) The therapeutic potential of iron chelators. Experimental Opinion Investigative Drugs, 8 12: 1-18. 29  
Becker, E., Watts, R. N., Lovejoy, D. B. and Richardson, D. R. (1999). Three classes of novel aroylhydrazone iron chelators and their structure-activity relationships. In: Proceedings of the International Conference on Oxidative Pathways in Health and Disease. Proceedings of the International Conference on Oxidative Pathways in Health and Disease, Veterinary Fac. Conference Cen., Univ. of Sydney, (). 1 - 4 Dec,1999. 39  
Bernhardt, P.V., Wilson, G.J., Sharpe, P.C., Kalinowski, D.S. and Richardson, D.R. (2008) Tuning the antiproliferative activity of biologically active iron chelators: characterization of the coordination chemistry and biological efficacy of 2-acetylpyridine and 2-benzoylpyridine hydrazone ligands. Journal of Biological Inorganic Chemistry, 13 1: 107-119. doi:10.1007/s00775-007-0300-4 64   40 Cited 37 times in Scopus37 0
Bernhardt, P. V., Chin, P. and Richardson, D. R. (2001) Unprecedented oxidation of a biologically active aroylhydrazone chelator catalysed by iron(III): serendipitous identification of diacylhydrazine ligands with high iron chelation efficacy. Journal of Biological Inorganic Chemistry, 6 8: 801-809. doi:10.1007/s007750100258 77   43 Cited 44 times in Scopus44 0