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Faridoon, Hussein, Waleed M., Vella, Peter, Ul Islam, Nazar, Ollis, David L., Schenk, Gerhard and McGeary, Ross P. (2012) 3-Mercapto-1,2,4-triazoles and N-acylated thiosemicarbazides as metallo-beta-lactamase inhibitors. Bioorganic and Medicinal Chemistry Letters, 22 1: 380-386. doi:10.1016/j.bmcl.2011.10.116 84   10 Cited 16 times in Scopus16 0
Jackson, Colin J., Carr, Paul D., Kim, Hye-Kyung, Liu, Jian-Wei, Herrald, Paul, Mitic, Natasa, Schenk, Gerhard, Smith, Clyde A. and Ollis, David L. (2006) Anomalous scattering analysis of Agrobacterium radiobacter phosphotriesterase: the prominent role of iron in the heterobinuclear active site. Biochemical Journal, 397 501-508. doi:10.1042/BJ20060276 88   39 Cited 38 times in Scopus38 0
Schenk, Gerhard, Mitić, Nataša, Gahan, Lawrence R., Ollis, David L., McGeary, Ross P. and Guddat, Luke W. (2012) Binuclear metallohydrolases: Complex mechanistic strategies for a simple chemical reaction. Accounts of Chemical Research, 45 9: 1593-1603. doi:10.1021/ar300067g 90   16 Cited 18 times in Scopus18 0
Mirams, Ruth E., Smith, Sarah J., Hadler, Kieran S., Ollis, David L., Schenk, Gerhard and Gahan, Lawrence R. (2008) Cadmium(II) complexes of the glycerophosphodiester-degrading enzyme GpdQ and a biomimetic N,O ligand. Journal of Biological Inorganic Chemistry, 13 7: 1065-1072. doi:10.1007/s00775-008-0392-5 69   9 Cited 9 times in Scopus9 0
Pedroso, Marcelo M., Ely, Fernanda, Mitic, Natasa, Carpenter, Margaret C., Gahan, Lawrence R., Wilcox, Dean E., Larrabee, James L., Ollis, David L. and Schenk, Gerhard (2014) Comparative investigation of the reaction mechanisms of the organophosphate-degrading phosphotriesterases from Agrobacterium radiobacter (OpdA) and Pseudomonas diminuta (OPH).. Journal of Biological Inorganic Chemistry, 19 8: 1263-1275. doi:10.1007/s00775-014-1183-9 20   0 Cited 0 times in Scopus0 0
Oakeshott, John G., Devonshire, Alan L., Claudianos, Charles, Sutherland, Tara D., Horne, Irene, Campbell, Peter M., Ollis, David L. and Russell, Robyn J. (2005). Comparing the organophosphorus and carbamate insecticide resistance mutations in cholin- and carboxyl-esterases. In: Vincenzo N. Talesa and Cinzia Antognelli, Chemico-Biological Interactions: Proceedings of the VIII International Meeting on Cholinesterases. VIII International Meeting on Cholinesterases, Perugia, Italy, (269-275). 26-30 September, 2004. doi:10.1016/j.cbi.2005.10.041 142   40 Cited 43 times in Scopus43 0
Pedroso, Marcelo M., Ely, Fernanda, Lonhienne, Thierry, Gahan, Lawrence R., Ollis, David L., Guddat, Luke W. and Schenk, Gerhard (2014) Determination of the catalytic activity of binuclear metallohydrolases using isothermal titration calorimetry. Journal of Biological Inorganic Chemistry, 19 3: 389-398. doi:10.1007/s00775-013-1079-0 46   1 Cited 0 times in Scopus0 0
Yip, Sylvia H-C., Foo, Jee-Loon, Schenk, Gerhard, Gahan, Lawrence R., Carr, Paul D. and Ollis, David L. (2011) Directed evolution combined with rational design increases activity of GpdQ toward a non-physiological substrate and alters the oligomeric structure of the enzyme. Protein Engineering Design and Selection, 24 12: 861-872. doi:10.1093/protein/gzr048 52   4 Cited 6 times in Scopus6 0
Jackson, Colin J., Gillam, Elizabeth M. J. and Ollis, David L. (2010). Directed evolution of enzymes. In Lewis Mander and Hung-Wen Liu (Ed.), Comprehensive natural products II chemistry and biology (pp. 723-749) Oxford, England, Unied Kingdom: Elsevier. 38  
Ely, Fernanda, Hadler, Kieran S., Mitic, Natasa, Gahan, Lawrence R., Ollis, David L., Plugis, Nicholas M., Russo, Marie T., Larrabee, James A. and Schenk, Gerhard (2011) Electronic and geometric structures of the organophosphate-degrading enzyme from Agrobacterium radiobacter (OpdA). Journal of Biological Inorganic Chemistry, 16 5: 777-787. doi:10.1007/s00775-011-0779-6 51   8 Cited 11 times in Scopus11 0
Hadler, Kieran S., Mitic, Natasa, Yip, Sylvia Hsu-Chen, Gahan, Lawrence R., Ollis, David L., Schenk, Gerhard and Larrabee, James A. (2010) Electronic structure analysis of the dinuclear metal center in the bioremediator glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes. Inorganic Chemistry, 49 6: 2727-2734. doi:10.1021/ic901950c 61   18 Cited 17 times in Scopus17 0
Vella, Peter, Miraula, Manfredi, Phelan, Emer, Leung, Eleanor W. W., Ely, Fernanda, Ollis, David L., McGeary, Ross P., Schenk, Gerhard and Mitić, Nataša (2013) Identification and characterization of an unusual metallo-beta-lactamase from Serratia proteamaculans. Journal of Biological Inorganic Chemistry, 18 7: 855-863. doi:10.1007/s00775-013-1035-z 67   2 Cited 2 times in Scopus2 0
Ugwumba, Isaac N., Ozawa, Kiyoshi, Xu, Zhi-Qiang, Ely, Fernanda, Foo, Jee-Loon, Herlt, Anthony J., Coppin, Chris, Brown, Sue, Taylor, Matthew C., Ollis, David L., Mander, Lewis N., Schenk, Gerhard, Dixon, Nicholas E., Otting, Gottfried, Oakeshott, John G. and Jackson, Colin J. (2011) Improving a natural enzyme activity through incorporation of unnatural amino acids. Journal of The American Chemical Society, 133 2: 326-333. doi:10.1021/ja106416g 77   17 Cited 20 times in Scopus20 0
Jackson, Colin J., Hadler, Kieran S., Carr, Paul D., Oakley, Aaron J., Yip, Sylvia, Schenk, Gerhard and Ollis, David L. (2008) Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) and characterization of the native Fe2+ metal-ion preference. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 64 8: 681-685. doi:10.1107/S1744309108017600 65   10 Cited 12 times in Scopus12 0
Phelan, Emer K., Miraula, Manfred, Selleck, Christopher, Ollis, David L., Schenk, Gerhard and Mitic, Natasa (2014) Metallo-β-lactamases: a major threat to human health. American Journal of Molecular Biology, 4 3: 89-104. doi:10.4236/ajmb.2014.43011 21   0
Foo, Jee‑Loon, Jackson, Colin J., Carr, Paul D., Kim, Hye‑Kyung, Schenk, Gerhard, Gahan, Lawrence R. and Ollis, David L. (2010) Mutation of outer-shell residues modulates metal ion co-ordination strength in a metalloenzyme. Biochemical Journal, 429 2: 313-321. doi:10.1042/BJ20100233 46   7 Cited 6 times in Scopus6 0
Ely, Fernanda, Pedroso, Marcelo M., Gahan, Lawrence R., Ollis, David L., Guddat, Luke W. and Schenk, Gerhard (2012) Phosphate-bound structure of an organophosphate-degrading enzyme from Agrobacterium radiobacter. Journal of Inorganic Biochemistry, 106 1: 19-22. doi:10.1016/j.jinorgbio.2011.09.015 59   6 Cited 6 times in Scopus6 0
Daumann, Lena J., McCarthy, Bianca Y., Hadler, Kieran S., Murray, Tracy P., Gahan, Lawrence R., Larrabee, James A., Ollis, David L. and Schenk, Gerhard (2013) Promiscuity comes at a price: catalytic versatility vs efficiency in different metal ion derivatives of the potential bioremediator GpdQ. Biochimica Et Biophysica Acta-Proteins and Proteomics, 1834 1: 425-432. doi:10.1016/j.bbapap.2012.02.004 31   5 Cited 5 times in Scopus5 0
Daumann, Lena J., Schenk, Gerhard, Ollis, David L. and Gahan, Lawrence R. (2014) Spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexes. Dalton Transactions, 43 3: 910-928. doi:10.1039/c3dt52287c 22   4 Cited 4 times in Scopus4 1
Hadler, Kieran S., Mitic, Natasa, Ely, Fernanda, Hanson, Graeme R., Gahan, Lawrence R., Larrabee, James A., Ollis, David L. and Schenk, Gerhard (2009) Structural flexibility enhances the reactivity of the bioremediator glycerophosphodiesterase by fine-tuning its mechanism of hydrolysis. Journal of the American Chemical Society, 131 33: 11900-11908. doi:10.1021/ja903534f 66   18 Cited 18 times in Scopus18 0
Hussein, Waleed M., Fatahala, Samar S., Mohamed, Zainab M., McGeary, Ross P., Schenk, Gerhard, Ollis, David L. and Mohamed, Mosaad S. (2012) Synthesis and kinetic testing of tetrahydropyrimidine-2-thione and pyrrole derivatives as inhibitors of the metallo-β-lactamase from Klebsiella pneumonia and Pseudomonas aeruginosa. Chemical Biology and Drug Design, 80 4: 500-515. doi:10.1111/j.1747-0285.2012.01440.x 72   10 Cited 11 times in Scopus11 1
Hadler, Kieran S., Gahan, Lawrence R., Ollis, David L. and Schenk, Gerhard (2009) The bioremediator glycerophosphodiesterase employs a non-processive mechanism for hydrolysis. Journal of Inorganic Biochemistry, 104 2: 211-213. doi:10.1016/j.jinorgbio.2009.10.012 62   8 Cited 8 times in Scopus8 0
Vella, Peter, Hussein, Waleed M., Leung, Eleanor W. W., Clayton, Daniel, Ollis, David L., Schenk, Gerhard and McGeary, Ross P. (2011) The identification of new metallo-beta-lactamase inhibitor leads from fragment-based screening. Bioorganic and Medicinal Chemistry Letters, 21 11: 3282-3285. doi:10.1016/j.bmcl.2011.04.027 291   15 Cited 16 times in Scopus16 0
Ely, Fernanda, Hadler, Kieran S., Gahan, Lawrence R., Guddat, Luke W., Ollis, David L. and Schenk, Gerhard (2010) The organophosphate-degrading enzyme from Agrobacterium radiobacter displays mechanistic flexibility for catalysis. Biochemical Journal, 432 3: 565-573. doi:10.1042/BJ20101054 68   13 Cited 13 times in Scopus13 0
Daumann, Lena J., Dalle, Kristian E., Schenk, Gerhard, McGeary, Ross P., Bernhardt, Paul V., Ollis, David L. and Gahan, Lawrence R. (2012) The role of Zn-OR and Zn-OH nucleophiles and the influence of para-substituents in the reactions of binuclear phosphatase mimetics. Dalton Transactions, 41 6: 1695-1708. doi:10.1039/c1dt11187f 68 3 17 Cited 18 times in Scopus18 0
Hou, Chun-Feng D., Phelan, Emer K., Miraula, Manfredi, Ollis, David L., Schenk, Gerhard and Mitić, Nataša (2014) Unusual metallo-beta-lactamases may constitute a new subgroup in this family of enzymes. American Journal of Molecular Biology, 4 1: 11-15. doi:10.4236/ajmb.2014.41002 7   0