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Behrendorff, James B. Y. H., Vickers, Claudia E., Chrysanthopoulos, Panagiotis and Nielsen, Lars K. (2013) 2,2-Diphenyl-1-picrylhydrazyl as a screening tool for recombinant monoterpene biosynthesis. Microbial Cell Factories, 12 76: 1-11. doi:10.1186/1475-2859-12-76 56   4 Cited 4 times in Scopus4 0
Brunck, Marion E. G., Andersen, Stacey B., Timmins, Nicholas E., Osborne, Geoffrey W. and Nielsen, Lars K. (2014) Absolute counting of neutrophils in whole blood using flow cytometry. Cytometry Part A, 85 12: 1057-1064. doi:10.1002/cyto.a.22503 34   0 1
Quek, Lake-Ee and Nielsen, Lars K (2014) A depth-first search algorithm to compute elementary flux modes by linear programming. BMC Systems Biology, 8 1: . doi:10.1186/s12918-014-0094-2 23   0 Cited 0 times in Scopus0 1
Dal'Molin, Cristiana Gomes de Oliveira, Quek, Lake-Ee, Palfreyman, Robin W. and Nielsen, Lars K. (2011) AlgaGEM - A genome-scale metabolic reconstruction of Algae based on Chlamydomonas reinhardtii genome. BMC Genomics, 12 Suppl. 4: s5.1-s5.10. doi:10.1186/1471-2164-12-S4-S5 84   21 Cited 18 times in Scopus18 0
Navone, Laura, Casati, Paula, Licona-Cassani, Cuauhtémoc, Marcellin, Esteban, Nielsen, Lars K., Rodriguez, Eduardo and Gramajo, Hugo (2014) Allantoin catabolism influences the production of antibiotics in Streptomyces coelicolor. Applied Microbiology and Biotechnology., 98 1: 351-360. doi:10.1007/s00253-013-5372-1 75   1 Cited 1 times in Scopus1 0
Brennan, Timothy C. R., Turner, Christopher D., Kroemer, Jens O. and Nielsen, Lars K. (2012) Alleviating monoterpene toxicity using a two-phase extractive fermentation for the bioproduction of jet fuel mixtures in Saccharomyces cerevisiae. Biotechnology and Bioengineering, 109 10: 2513-2522. doi:10.1002/bit.24536 77   19 Cited 21 times in Scopus21 1
Li, Juan, Wijffels, Gene, Yu, Yihua, Nielsen, Lars K., Niemeyer, Dominic O., Fisher, Andrew D., Ferguson, Drewe M. and Schirra, Horst Joachim (2011) Altered fatty acid metabolism in long duration road transport: An NMR-based metabonomics study in sheep. Journal of Proteome Research, 10 3: 1073-1087. doi:10.1021/pr100862t 74   7 Cited 8 times in Scopus8 0
Dietmair, Stefanie, Hodson, Mark P., Quek, Lake-Ee, Timmins, Nicholas E., Gray, Peter and Nielsen, Lars K. (2012) A multi-omics analysis of recombinant protein production in Hek293 cells. Plos One, 7 8: e43394.1-e43394.15. doi:10.1371/journal.pone.0043394 75   10 Cited 12 times in Scopus12 1
de Oliveira Dal'molin, Cristiana Gomes, Quek, Lake-Ee, Saa, Pedro A. and Nielsen, Lars K. (2015) A multi-tissue genome-scale metabolic modelling framework for the analysis of whole plant systems. Frontiers in Plant Science, 6 JAN: 4.1-4.12. doi:10.3389/fpls.2015.00004 70   0 Cited 0 times in Scopus0 1
Haas, Richard and Nielsen, Lars K. (2005) A physiological product-release model for baculovirus infected insect cells. Biotechnology And Bioengineering, 91 6: 768-772. doi:10.1002/bit.20565 100   6 Cited 7 times in Scopus7 0
Bruschi, Michele, Boyes, Simon J., Sugiarto, Haryadi, Nielsen, Lars K. and Vickers, Claudia E. (2012) A transferable sucrose utilization approach for non-sucrose-utilizing Escherichia coli strains. Biotechnology Advances, 30 5: 1001-1010. doi:10.1016/j.biotechadv.2011.08.019 70   5 Cited 9 times in Scopus9 0
Doran, Michael R., Aird, Ian Alexander, Marturana, Flavia, Timmins, Nicholas, Atkinson, Kerry and Nielsen, Lars K. (2012) Bioreactor for blood product production. Cell Transplantation, 21 6: 1235-1244. doi:10.3727/096368911X627363 93   1 Cited 1 times in Scopus1 6
Marcellin Saldana, Esteban Stefane, Mercer, Timothy, Licona Cassani, Cuauthemoc and Nielsen, Lars K. (2011). Building Systems biology platforms for Actinobacteria. In: ISBA XVI, Puerto Vallarta, Mexico, (). 11-15 December 2011. 36  
Petrasovits, Lars A., McQualter, Richard B., Gebbie, Leigh K., Blackman, Deborah M., Nielsen, Lars K. and Brumbley, Stevens M. (2013) Chemical inhibition of acetyl coenzyme A carboxylase as a strategy to increase polyhydroxybutyrate yields in transgenic sugarcane. Plant Biotechnology Journal, 11 9: 1146-1151. doi:10.1111/pbi.12109 51   2 Cited 2 times in Scopus2 0
Brunck, Marion E. G. and Nielsen, Lars K. (2014) Concise review: next-generation cell therapies to prevent infections in neutropenic patients. Stem Cells Translational Medicine, 3 4: 541-548. doi:10.5966/sctm.2013-0145 41 2 0 Cited 0 times in Scopus0 0
Quek, Lake-Ee and Nielsen, Lars K. (2014). Customization of 13C-MFA Strategy According to Cell Culture System. In Jens O. Kromer, Lars K. Nielsen and Lars M. Blank (Ed.), Metabolic Flux Analysis: Methods and Protocols (pp. 81-90) New York, NY United States: Humana Press. doi:10.1007/978-1-4939-1170-7_5 69   Cited 0 times in Scopus0 0
Huynh, Hoai T., Tran, Trinh T. B., Chan, Leslie C. L., Nielsen, Lars K. and Reid, Steven (2013) Decline in baculovirus-expressed recombinant protein production with increasing cell density is strongly correlated to impairment of virus replication and mRNA expression. Applied Microbiology and Biotechnology, 97 12: 5245-5257. doi:10.1007/s00253-013-4835-8 49   2 Cited 2 times in Scopus2 0
Etebari, Kayvan, Palfreyman, Robin W., Schlipalius, David, Nielsen, Lars K., Glatz, Richard V. and Asgari, Sassan (2011) Deep sequencing-based transcriptome analysis of Plutella xylostella larvae parasitized by Diadegma semiclausum. BMC Genomics, 12 446.1-446.18. doi:10.1186/1471-2164-12-446 75   30 Cited 30 times in Scopus30 0
Arifin, Yalun, Sabri, Suriana, Sugiarto, Haryadi, Krömer, Jens O., Vickers, Claudia E. and Nielsen, Lars K. (2011) Deletion of cscR in Escherichia coli W improves growth and poly-3-hydroxybutyrate (PHB) production from sucrose in fed batch culture. Journal of Biotechnology, 156 4: 275-278. doi:10.1016/j.jbiotec.2011.07.003 67   7 Cited 9 times in Scopus9 0
Marcellin, Esteban, Segovia, Simon, De Tissera, Sashini, Mitchell, Wayne, Kopke, Michael and Nielsen, Lars K. (2014). Developing an integrated systems and synthetic biology platform for gas fermentation. In: Metabolic Engineering X, Vancouver, BC, Canada, (). 15-19 June 2014. 27  
Song, Hyohak, Kim, Tae Yong, Choi, Bo-Kyeong, Choi, Seong Jun, Nielsen, Lars K., Chang, Ho Nam and Lee, Sang Yup (2008) Development of chemically defined medium for Mannheimia succiniciproducens based on its genome sequence. Applied Microbiology and Biotechnology., 79 2: 263-272. doi:10.1007/s00253-008-1425-2 73   24 Cited 26 times in Scopus26 0
Tran, Trinh T.B., Dietmair, Stefanie, Chan, Leslie C.L., Huynh, Hoai T., Nielsen, Lars K. and Reid, Steven (2012) Development of quenching and washing protocols for quantitative intracellular metabolite analysis of uninfected and baculovirus-infected insect cells. Methods, 56 3: 396-407. doi:10.1016/j.ymeth.2011.11.009 70   5 Cited 5 times in Scopus5 1
Lee, Jeong Wook, Choi, Sol, Park, Jin Hwan, Vickers, Claudia E., Nielsen, Lars K. and Lee, Sang Yup (2010) Development of sucrose-utilizing Escherichia coli K-12 strain by cloning beta-fructofuranosidases and its application for L-threonine production. Applied Microbiology and Biotechnology, 88 4: 905-913. doi:10.1007/s00253-010-2825-7 77   16 Cited 17 times in Scopus17 0
Brumbley, Stevens M., Purnell, Matt P., Petrasovits, Lars A., O'Shea, Michael G. and Nielsen, Lars K. (2004). Development of sugarcane as a biofactory for biopolymers. In: Proceedings of Plant & Animal Genomes XII Conference. Plant & Animal Genomes XII Conference, San Diego, U.S., (). 10-14 January 2004. 243  
Mercer, Tim R., Edwards, Stacey L., Clark, Michael B., Neph, Shane J., Wang, Hao, Stergachis, Andrew B., John, Sam, Sandstrom, Richard, Li, Guoliang, Sandhu, Kuljeet S., Ruan, Yijun, Nielsen, Lars K., Mattick, John S. and Stamatoyannopoulos, John A. (2013) DNase I-hypersensitive exons colocalize with promoters and distal regulatory elements. Nature Genetics, 45 8: 852-859. doi:10.1038/ng.2677 32   23 Cited 17 times in Scopus17 88
Licona Cassani, Cuauthemoc, Marcellin Saldana, Esteban Stefane and Nielsen, Lars K. (2012). Dynamic analysis of Saccharopolyspora erythraea life cycle in bioreactors; a systems approach. In: Actinobacteria within soil, Munster, Germany, (). 25-28 October 2012. 32  
Jardine, Kolby, Chambers, Jeffrey, Alves, Eliane G., Teixeira, Andrea, Garcia, Sabrina, Holm, Jennifer, Higuchi, Niro, Manzi, Antonio, Abrell, Leif, Fuentes, Jose D., Nielsen, Lars K., Torn, Margaret S. and Vickers, Claudia E. (2014) Dynamic balancing of isoprene carbon sources reflects photosynthetic and photorespiratory responses to temperature stress. Plant Physiology, 166 4: 2051-2064. doi:10.1104/pp.114.247494 21   0 Cited 1 times in Scopus1 0
Licona Cassani, Cuauthemoc, Marcellin Saldana, Esteban Stefane and Nielsen, Lars K. (2011). Dynamic System-level study for protein expression in Saccharopolyspora erythraea. In: 16th International Symposium on the Biology of Actinomycetes, Puerto Vallarta, Mexico, (). 11-15 December 2011. 30  
Huynh, Hoai T., Tran, Trinh T. B., Chan, Leslie C. L., Nielsen, Lars K. and Reid, Steven (2014) Effect of the peak cell density of recombinant AcMNPV-infected Hi5 cells on baculovirus yields. Applied Microbiology and Biotechnology, 99 4: 1687-1700. doi:10.1007/s00253-014-6260-z 28   0 Cited 0 times in Scopus0 0
Williams, Thomas C., Nielsen, Lars K. and Vickers, Claudia E. (2013) Engineered quorum-sensing using pheromone-mediated cell-to-cell communication in Saccharomyces cerevisiae. ACS Synthetic Biology, 2 3: 136-149. doi:10.1021/sb300110b 91   6 Cited 7 times in Scopus7 20
Dietmair, Stefanie, Nielsen, Lars K. and Timmins, Nicholas E. (2011) Engineering a mammalian super producer. Journal of Chemical Technology and Biotechnology, 86 7: 905-914. doi:10.1002/jctb.2576 62   10 Cited 11 times in Scopus11 0
Utrilla, Jose, Licona-Cassani, Cuauhtemoc, Marcellin, Esteban, Gosset, Guillermo, Nielsen, Lars K. and Martinez, Alfredo (2012) Engineering and adaptive evolution of Escherichia coli for D-lactate fermentation reveals GatC as a xylose transporter. Metabolic Engineering, 14 5: 469-476. doi:10.1016/j.ymben.2012.07.007 46   7 Cited 9 times in Scopus9 1
Petrasovits, Lars A., Zhao, Lihan, McQualter, Richard B., Snell, Kristi D., Somleva, Maria N., Patterson, Nii A., Nielsen, Lars K. and Brumbley, Stevens M (2012) Enhanced polyhydroxybutyrate production in transgenic sugarcane. Plant Biotechnology Journal, 10 5: 569-578. doi:10.1111/j.1467-7652.2012.00686.x 90   11 Cited 11 times in Scopus11 0
Arifin, Yalun, Archer, Colin, Lim, SooA, Quek, Lake-Ee, Sugiarto, Haryadi, Marcellin, Esteban, Vickers, Claudia E., Kromer, Jens O. and Nielsen, Lars K. (2014) Escherichia coli W shows fast, highly oxidative sucrose metabolism and low acetate formation. Applied Microbiology and Biotechnology, 98 21: 9033-9044. doi:10.1007/s00253-014-5956-4 27   0 Cited 0 times in Scopus0 0
Lars M. Blank, Philip Hugenholtz and Nielsen, Lars K. (2008) Evolution of Hyaluronic Acid Synthesis (has) Operon in Streptococcus zooepidemicus and other Pathogenic Streptococci. Journal of Molecular Evolution, 67 1: 13-22. doi:10.1007/s00239-008-9117-1 118   24 Cited 28 times in Scopus28 0
Fearnley, Liam, Davis, Melissa, Ragan, Mark A. and Nielsen, Lars K. (2013) Extracting reaction networks from databases-opening Pandora's box. Briefings in Bioinformatics, 15 6: 973-983. doi:10.1093/bib/bbt058 38   0 Cited 1 times in Scopus1 20
McQualter, Richard B., Somleva, Maria N., Gebbie, Leigh K., Li, Xuemei, Petrasovits, Lars A., Snell, Kristi D., Nielsen, Lars K. and Brumbley, Stevens M. (2014) Factors affecting polyhydroxybutyrate accumulation in mesophyll cells of sugarcane and switchgrass. BMC Biotechnology, 14 1: 83.1-83.11. doi:10.1186/1472-6750-14-83 17   0 Cited 0 times in Scopus0 1
Sang Up Lee, Jin Hwan Park, Seh Hee Jang, Nielsen, Lars K., Jaehyun Kim and Kwang S.Jung (2008) Fermentative Butanol Production by Clostridia. Biotechnology and Bioengineering, 101 2: 209-228. doi:10.1002/bit.22003 198   287 Cited 325 times in Scopus325 6
Martínez, Verónica S., Dietmair, Stefanie, Quek, Lake-Ee, Hodson, Mark P., Gray, Peter and Nielsen, Lars K. (2013) Flux balance analysis of CHO cells before and after a metabolic switch from lactate production to consumption. Biotechnology and Bioengineering, 110 2: 660-666. doi:10.1002/bit.24728 93   12 Cited 14 times in Scopus14 0
Peng, Judy C., Thomas, Ranjeny and Nielsen, Lars K. (2005) Generation and maturation of dendritic cells for clinical application under serum-free conditions. Journal of Immunotherapy, 28 6: 599-609. doi:10.1097/01.cji.0000175491.21099.04 229   32 Cited 31 times in Scopus31 0
Timmins, Nicholas E. and Nielsen, Lars K. (2007). Generation of Multicellular Tumour Spheroids by the Hanging Drop Method. In John M. Walker (Ed.), Tissue Engineering 2 ed. (pp. 141-151) Totowa, N. J.: Humana Press. 171  
Nguyen, Quan, Chan, Leslie C. L., Nielsen, Lars K. and Reid, Steven (2013) Genome scale analysis of differential mRNA expression of Helicoverpa zea insect cells infected with a H. armigera baculovirus. Virology, 444 1-2: 158-170. doi:10.1016/j.virol.2013.06.004 42   2 Cited 2 times in Scopus2 0
Dal'Molin, Cristiana G., Quek, Lake-ee and Nielsen, Lars K. (2008). Genome scale metabolic network model of Arabidopsis. In: Health And Sustainability: Metabolic Engineering VII, Puerto Vallarta, Mexico, (). 14-18 September 2008. 58  
Nguyen,Quan, Nielsen, Lars K. and Reid, Steven (2013) Genome scale transcriptomics of baculovirus-insect interactions. Viruses, 5 11: 2721-2747. doi:10.3390/v5112721 45   3 Cited 3 times in Scopus3 3
Mercer, Tim R., Clark, Michael B., Anderson, Stacey B., Brunck, Marion E., Haerty, Wilifried, Crawford, Joanna, Taft, Ryan J., Nielsen, Lars K., Dinger, Marcel E. and Mattick, John S. (2015) Genome-wide discovery of human splicing branchpoints. Genome Research, 25 2: 290-303. doi:10.1101/gr.182899.114 18   0 Cited 0 times in Scopus0 17
Orellana, Camila A., Marcellin, Esteban, Schulz, Benjamin L., Nouwens, Amanda S., Gray, Peter P. and Nielsen, Lars K. (2015) High-antibody-producing Chinese hamster ovary cells up-regulate intracellular protein transport and glutathione synthesis. Journal of Proteome Research, 14 2: 609-618. doi:10.1021/pr501027c 19   0 Cited 0 times in Scopus0 2
Wicks, John Richard, Oldridge, Neil B., Nielsen, Lars K. and Vickers, Claudia E. (2011) HR index-a simple method for the prediction of oxygen uptake. Medicine and Science in Sports and Exercise, 43 10: 2005-2012. doi:10.1249/MSS.0b013e318217276e 143 2 10 Cited 10 times in Scopus10 0
Pedrini, Márcia R. S., Christian, Peter, Nielsen, Lars K., Reid, Steven and Chan, Leslie C. L. (2006) Importance of virus–medium interactions on the biological activity of wild-type Heliothine nucleopolyhedroviruses propagated via suspension insect cell cultures. Journal of Virological Methods, 136 1-2: 267-272. doi:10.1016/j.jviromet.2006.04.007 617 245 5 Cited 7 times in Scopus7 0
Huynh, Hoai T., Chan, Leslie C. L., Tran, Trinh T. B., Nielsen, Lars K. and Reid, Steven (2012) Improving the robustness of a low-cost insect cell medium for baculovirus biopesticides production, via hydrolysate streamlining using a tube bioreactor-based statistical optimization routine. Biotechnology Progress, 28 3: 788-802. doi:10.1002/btpr.1529 70   5 Cited 7 times in Scopus7 0
Koebmann, Brian, Blank, Lars Mathias, Solem, Christian, Petranovic, Dina, Nielsen, Lars K. and Jensen, Peter Ruhdal (2008) Increased biomass yield of Lactococcus lactis during energetically limited growth and respiratory conditions. Biotechnology & Applied Biochemistry, 50 Pt. 1: 25-33. doi:10.1042/BA20070132 93   12 Cited 11 times in Scopus11 0

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