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Thundyil, John, Pavlovski, Dale, Hsieh, Yu-Hsuan, Gelderblom, Mathias, Magnus, Tim, Fairlie, David P. and Arumugam, Thiruma V. (2012) C5a receptor (CD88) and TLR2 inhibition improves hypothermia-induced neuroprotection in an in vitro ischemic model. NeuroMolecular Medicine, 14 1: 30-39. doi:10.1007/s12017-012-8167-0 121   5 Cited 5 times in Scopus5 0
Manzanero, Silvia, Gelderblom, Mathias, Magnus, Tim and Arumugam, Thiruma V. (2011) Calorie restriction and stroke. Experimental and Translational Stroke Medicine, 3 8.1-8.35. doi:10.1186/2040-7378-3-8 52   Cited 15 times in Scopus15 0
Arumugam, Thiruma V., Magnus, Tim, Woodruff, Trent M., Proctor, Lavinia M., Shiels, Ian A., Taylor, Stephen M., A. H. Wu and J. Delanghe (2006) Complement mediators in ischemia-reperfusion injury. Clinica Chimica Acta, 374 1-2: 33-45. doi:10.1016/j.cca.2006.06.010 68   61 Cited 64 times in Scopus64 0
Cheng, Yi-Lin, Park, Jong-Sung, Manzanero, Silvia, Choi, Yuri, Baik, Sang-Ha, Okun, Eitan, Gelderblom, Mathias, Fann, David Yang-Wei, Magnus, Tim, Launikonis, Bradley S., Mattson, Mark P., Sobey, Christopher G., Jo, Dong-Gyu and Arumugam, Thiruma V. (2014) Evidence that collaboration between HIF-1alpha and Notch-1 promotes neuronal cell death in ischemic stroke. Neurobiology of Disease, 62 286-295. doi:10.1016/j.nbd.2013.10.009 56   5 Cited 5 times in Scopus5 0
Arumugam, Thiruma V., Cheng, Yi-Lin, Choi, Yuri, Choi, Yun-Hyung, Yang, Sunghee, Yun, Young-Kwang, Park, Jong-Sung, Yang, Dong Kwon, Thundyil, John, Gelderblom, Mathias, Karamyan, Vardan T., Tang, Sung-Chun, Chan, Sic L., Magnus, Tim, Sobey, Christopher G. and Jo, Dong-Gyu (2011) Evidence that {gamma}-Secretase-mediated Notch signaling induces neuronal cell death via the nuclear factor-{kappa}B-Bcl-2-interacting mediator of cell death pathway in ischemic stroke. Molecular Pharmacology, 80 1: 23-31. doi:10.1124/mol.111.071076 44   27 Cited 29 times in Scopus29 0
Magnus, Tim, Coksaygan, Turhan, Korn, Thomas, Xue, Haipeng, Arumugam, Thiruma V., Mughal, Mohamed R., Eckley, D. Mark, Tang, Sung-Chun, DeTolla, Louis, Rao, Mahendra S., Cassiani-Ingoni, Riccardo and Mattson, Mark P. (2007) Evidence that nucleocytoplasmic Olig2 translocation mediates brain-injury-induced differentiation of glial precursors to astrocytes. Journal of Neuroscience Research, 85 10: 2126-2137. doi:10.1002/jnr.21368 68   53 Cited 54 times in Scopus54 0
Arumugam, Thiruma V., Chan, Sic L., Jo, Dong-Gyu, Yilmaz, Gokhan, Tang, Sung-Chun, Cheng, Aiwu, Gleichmann, Marc, Okun, Eitan, Dixit, Vishwa D., Chigurupati, Srinivasulu, Mughal, Mohamed R., Ouyang, Xin, Miele, Lucio, Magnus, Tim, Poosala, Suresh, Granger, D. Neil and Mattson, Mark P. (2006) Gamma secretase-mediated notch signaling worsens brain damage and functional outcome in ischemic stroke. Nature Medicine, 12 6: 621-623. doi:10.1038/nm1403 68   115 Cited 116 times in Scopus116 0
Widiapradja, Alexander, Vegh, Viktor, Lok, Ker Zhing, Manzanero, Silvia, Thundyil, John, Gelderblom, Mathias, Cheng, Yi-Lin, Pavlovski, Dale, Tang, Sung-Chun, Jo, Dong-Gyu, Magnus, Tim, Chan, Sic L., Sobey, Christopher G., Reutens, David, Basta, Milan, Mattson, Mark P. and Arumugam, Thiruma V. (2012) Intravenous immunoglobulin protects neurons against amyloid beta-peptide toxicity and ischemic stroke by attenuating multiple cell death pathways. Journal of Neurochemistry, 122 2: 321-332. doi:10.1111/j.1471-4159.2012.07754.x 90   13 Cited 14 times in Scopus14 2
Tang, Sung-Chun, Arumugam, Thiruma V., Cutler, Roy G., Jo, Dong-Gyu, Magnus, Tim, Chan, Sic L., Mughal, Mohamed R., Telljohann, Richard S., Nassar, Matthew, Xin, Ouyang, Calderan, Andrea, Ruzza, Paolo, Guiotto, Andrea and Mattson, Mark P. (2007) Neuroprotective actions of a histidine analogue in models of ischemic stroke. Journal of Neurochemistry, 101 3: 729-736. doi:10.1111/j.1471-4159.2006.04412.x 40   38 Cited 40 times in Scopus40 0
Gelderblom, Mathias, Weymar, Anna, Bernreuther, Christian, Velden, Joachim, Arunachalam, Priyadharshini, Steinbach, Karin, Orthey, Ellen, Arumugam, Thiruma V., Leypoldt, Frank, Simova, Olga, Thom, Vivien, Friese, Manuel, Prinz, Immo, Holscher, Christoph, Glatzel, Markus, Korn, Thomas, Gerloff, Christian, Tolosa, Eva and Magnus, Tim (2012) Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke. Blood, 120 18: 3793-3802. doi:10.1182/blood-2012-02-412726 56   43 Cited 42 times in Scopus42 2
Low, Pei Ching, Manzanero, Silvia, Mohannak, Nika, Narayana, Vinod K., Nguyen, Tam H., Kvaskoff, David, Brennan, Faith H., Ruitenberg, Marc J., Gelderblom, Mathias, Magnus, Tim, Kim, Hyun Ah, Broughton, Brad R. S., Sobey, Christopher G., Vanhaesebroeck, Bart, Stow, Jennifer L., Arumugam, Thiruma V. and Meunier, Frédéric A. (2014) PI3K delta inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model. Nature Communications, 5 3450: 1-12. doi:10.1038/ncomms4450 66   5 19
Tang, Sung-Chun, Arumugam, Thiruma V., Xu, Xiangru, Cheng, Aiwu, Mughal, Mohamed R., Jo, Dong Gyu, Lathia, Justin D., Siler, Dominic A., Chigurupati, Srinivasulu, Ouyang, Xin, Magnus, Tim, Camandola, Simonetta and Mattson, Mark P. (2007) Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits. Proceedings of the National Academy of Sciences of the United States of America, 104 34: 13798-13803. doi:10.1073/pnas.0702553104 31   301 Cited 310 times in Scopus310 1
Gelderblom, Mathias, Leypoldt, Frank, Lewerenz, Jan, Birkenmayer, Gabriel, Orozco, Denise, Ludewig, Peter, Thundyil, John, Arumugam, Thiruma V., Gerloft, Christian, Tolosa, Eva, Maher, Pamela and Magnus, Tim (2012) The flavonoid fisetin attenuates postischemic immune cell infiltration, activation and infarct size after transient cerebral middle artery occlusion in mice. Journal of Cerebral Blood Flow and Metabolism, 32 5: 835-843. doi:10.1038/jcbfm.2011.189 37   20 Cited 21 times in Scopus21 0
Lathia, Justin D., Okun, Eitan, Tang, Sung-Chun, Griffioen, Kathleen, Cheng, Aiwu, Mughal, Mohamed R., Laryea, Gloria, Selvaraj, Pradeep K., ffrench-Constant, Charles, Magnus, Tim, Arumugam, Thiruma V. and Mattson, Mark P. (2008) Toll-like receptor 3 is a negative regulator of embryonic neural progenitor cell proliferation. Journal of Neuroscience, 28 51: 13978-13984. doi:10.1523/JNEUROSCI.2140-08.2008 42   64 Cited 63 times in Scopus63 0