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Liu, Ligong, Li, Caiping, Cochran, Siska, Feder, Daniel, Guddat, Luke W. and Ferro, Vito (2012) A focused sulfated glycoconjugate Ugi library for probing heparan sulfate-binding angiogenic growth factors. Bioorganic & Medicinal Chemistry Letters, 22 19: 6190-6194. doi:10.1016/j.bmcl.2012.08.001 52   2 Cited 1 times in Scopus1 1
Eckle, Sidonia B.G., Birkinshaw, Richard W., Kostenko, Lyudmila, Corbett, Alexandra J., McWilliam, Hamish E. G., Reantragoon, Rangsima, Chen, Zhenjun, Gherardin, Nicholas A., Beddoe, Travis, Liu, Ligong, Patel, Onisha, Meehan, Bronwyn, Fairlie, David P., Villadangos, Jose A., Godfrey, Dale I., Kjer-Nielsen, Lars, McCluskey, James and Rossjohn, Jamie (2014) A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells. Journal of Experimental Medicine, 211 8: 1585-1600. doi:10.1084/jem.20140484 25   6 Cited 8 times in Scopus8 2
Lohman, Rink-Jan, Cotterell, Adam J., Barry, Grant D., Liu, Ligong, Suen, Jacky Y., Vesey, David A. and Fairlie, David P. (2012) An antagonist of human protease activated receptor-2 attenuates PAR2 signaling, macrophage activation, mast cell degranulation, and collagen-induced arthritis in rats. The FASEB Journal, 26 7: 2877-2887. doi:10.1096/fj.11-201004 87   20 Cited 23 times in Scopus23 1
Lohman, Rink-Jan, Cotterell, Adam J., Suen, Jacky, Liu, Ligong, Do, Anh T., Vesey, David A. and Fairlie, David P. (2012) Antagonism of protease-activated receptor 2 protects against experimental colitis.. Journal of Pharmacology and Experimental Therapeutics, 340 2: 256-265. doi:10.1124/jpet.111.187062 65   20 Cited 20 times in Scopus20 0
Reantragoon, Rangsima, Corbett, Alexandra J., Sakala, Isaac G., Gherardin, Nicholas A., Furness, John B., Chen, Zhenjun, Eckle, Sidonia B. G., Uldrich, Adam P., Birkinshaw, Richard W., Patel, Onisha, Kostenko, Lyudmila, Meehan, Bronwyn, Kedzierska, Katherine, Liu, Ligong, Fairlie, David P., Hansen, Ted H., Godfrey, Dale I., Rossjohn, Jamie, McCluskey, James and Kjer-Nielsen, Lars (2013) Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells. Journal of Experimental Medicine, 210 11: 2305-2320. doi:10.1084/jem.20130958 36   29 Cited 28 times in Scopus28 10
Thanh, Giang Le, Abbenante, Giovanni, Adamson, George, Becker, Bernd, Clark, Chris, Condie, Glenn, Falzun, Tania, Grathwohl, Matthias, Gupta, Praveer, Hanson, Michael, Huynh, Ngoc, Katavic, Peter, Kuipers, Krystle, Lam, Ann, Liu, Ligong, Mann, Maretta, Mason, Jeff, McKeveney, Declan, Muldoon, Craig, Pearson, Andrew, Rajaratnam, Premraj, Ryan, Sarah, Tometzki, Gerry, Verquin, Geraldine, Waanders, Jennifer, West, Michael, Wilcox, Neil, Wimmer, Norbert, Yau, Annika, Zuegg, Johannes and Meutermans, Wim (2010) A versatile synthetic approach toward diversity libraries using monosaccharide scaffolds. Journal of Organic Chemistry, 75 1: 197-203. doi:10.1021/jo9021919 99   1 Cited 7 times in Scopus7 0
Abbenante, Giovanni, Becker, Bernd, Blanc, Sebastien, Clark, Chris, Condie, Glenn, Fraser, Graeme, Grathwohl, Matthias, Halliday, Judy, Henderson, Senka, Lam, Ann, Liu, Ligong, Mann, Maretta, Muldoon, Craig, Pearson, Andrew, Premraj, Rajaratnam, Ramsdale, Tracie, Rossetti, Tony, Schafer, Karl, Le Thanh, Giang, Tometzki, Gerald, Vari, Frank, Verquin, Geraldine, Waanders, Jennifer, West, Michael, Wimmer, Norbert, Yau, Annika, Zuegg, Johannes and Meutermans, Wim (2010) Biological diversity from a structurally diverse library: Systematically scanning conformational space using a pyranose scaffold. Journal of Medicinal Chemistry, 53 15: 5576-5586. doi:10.1021/jm1002777 70   8 Cited 8 times in Scopus8 0
Hill, Timothy A., Lohman, Rink-Jan, Hoang, Huy N., Nielsen, Daniel S., Scully, Conor C. G., Kok, W. Mei, Liu, Ligong, Lucke, Andrew J., Stoermer, Martin J., Schroeder, Christina I., Chaousis, Stephanie, Colless, Barbara, Bernhardt, Paul V., Edmonds, David J., Griffith, David A., Rotter, Charles J., Ruggeri, Roger B., Price, David A., Liras, Spiros, Craik, David J. and Fairlie, David P. (2014) Cyclic penta- and hexaleucine peptides without N-methylation are orally absorbed. ACS Medicinal Chemistry Letters, 5 10: 1148-1151. doi:10.1021/ml5002823 37   0 Cited 1 times in Scopus1 1
West, Michael Leo, Andrews, Peter, Ramsdale, Tracie Elizabeth, Meutermans, Wim, Thanh Le, Giang, Clark, Chris, Abbenante, Giovani and Liu, Ligong (2004). Derivatives of synthesis of monosaccharides for drug discovery. WO 2004014929. 70  
Liu, Ligong, Bytheway, Ian, Karoli, Tomislav, Fairweather, Jon K., Cochran, Siska, Li, Caiping and Ferro, Vito (2008) Design, synthesis, FGF-1 binding, and molecular modeling studies of conformationally flexible heparin mimetic disaccharides. Bioorganic & Medicinal Chemistry Letters, 18 1: 344-349. doi:10.1016/j.bmcl.2007.10.071 65   10 Cited 9 times in Scopus9 0
Lim, Junxian, Iyer, Abishek, Liu, Ligong, Suen, Jacky Y., Lohman, Rink-Jan, Seow, Vernon, Yau, Mei-Kwan, Brown, Lindsay and Fairlie, David P. (2013) Diet-induced obesity, adipose inflammation, and metabolic dysfunction correlating with PAR2 expression are attenuated by PAR2 antagonism. The FASEB Journal, 27 12: 4757-4767. doi:10.1096/fj.13-232702 61   10 Cited 8 times in Scopus8 78
Ferro, Vito, Liu, Ligong, Johnstone, Ken D., Wimmer, Norbert, Karoli, Tomislav, Handley, Paul, Rowley, Jessica, Dredge, Keith, Li, Cai Ping, Hammond, Edward, Davis, Kat, Sarimaa, Laura, Harenberg, Job and Bytheway, Ian (2012) Discovery of PG545: A highly potent and simultaneous inhibitor of angiogenesis, tumor growth, and metastasis. Journal of Medicinal Chemistry, 55 8: 3804-3813. doi:10.1021/jm201708h 94   24 Cited 23 times in Scopus23 1
Liu, Ligong (2003) Enantioselective synthesis of protoberberine alkaloids via -sparteine-mediated asymmetric condensation-cyclisation of o-toluamide anions with 3,4-dihydroisoquinolines. Synthesis, 11 1705-1706. 43   Cited 25 times in Scopus25
Don, Robert Hugh, Ferro, Vito, Bytheway, Ian, Cochran, Siska, Fairweather, Jon Krueger, Hammond, Edward Timothy, Karoli, Tomislav, Li, Cai Ping and Liu, Ligong (2005). Glycosaminoglycan (GAG) mimetics. WO/2005/061523. 69  
Gupta, Praveer K., Reid, Robert C., Liu, Ligong, Lucke, Andrew J., Broomfield, Steve A., Andrews, Melanie R., Sweet, Matthew J. and Fairlie, David P. (2010) Inhibitors selective for HDAC6 in enzymes and cells. Bioorganic & Medicinal Chemistry Letters, 20 23: 7067-7070. doi:10.1016/j.bmcl.2010.09.100 65   14 Cited 13 times in Scopus13 0
Banwell, Martin Gerhardt, Liu, Ligong, Parish, Christopher Richard and Freeman, Craig Geoffrey (2003). Linked cyclitols and their polysulfated derivatives. WO/2003/004454. 69  
Van Vliet, Liisa D., Ellis, Tom, Foley, Patrick J., Liu, Ligong, Pfeffer, Frederick M., Russell, Richard A., Warrener, Ronald N., Hollfielder, Florian and Waring, Michael J. (2007) Molecular Recognition of DNA by Rigid [n]-Polynorbornane-Derived Bifunctional Intercalators: Synthesis and Evaluation of Their Binding Properties. Journal of medicinal chemistry, 50 10: 2326-2340. doi:10.1021/jm0613020 25   25 Cited 28 times in Scopus28 0
Kjer-Nielsen, Lars, Patel, Onisha, Corbett, Alexandra J., Le Nours, Jerome, Meehan, Bronwyn, Liu, Ligong, Bhati, Mugdha, Chen, Zhenjun, Kostenko, Lyudmila, Reantragoon, Rangsima, Williamson, Nicholas A., Purcell, Anthony W., Dudek, Nadine L., McConville, Malcolm J., O'Hair, Richard A. J., Khairallah, George N., Godfrey, Dale I., Fairlie, David P., Rossjohn, Jamie and McCluskey, James (2012) MR1 presents microbial vitamin B metabolites to MAIT cells. Nature, 491 7426: 717-725. doi:10.1038/nature11605 54   110 Cited 108 times in Scopus108 16
Yau, Annika M., Liu, Ligong, Reid, Robert C., Barry, Grant D., Suen, Jacky Y., Lohman, Rink-Jan, Le, Giang T., Cotterell, Adam and Fairlie, David P. (2011). Novel agonists and antagonists for protease activated receptor 2. In: Abstracts of Papers of the 242nd National Meeting of the American Chemical Society. National Meeting of the American Chemical Society (242nd, ACS, 2011), Denver, CO, U.S.A., (). 28 August-1 September 2011. 57   0
Rajaratnam, Premraj, Gupta, Praveer, Katavic, Peter, Kuipers, Krystle, Huyh, Ngoc, Ryan, Sarah, Falzun, Tania, Tometzki, Gerrald B., Bornaghi, Laurent, Le Thanh, Giang, Abbenante, Giovanni, Liu, Ligong, Meutermans, Wim, Wimmer, Norbert and West, Michael L. (2010) Orthogonally Protected Monosaccharide Building Blocks for Solid Phase Production of Diversity Oriented Libraries. Australian Journal of Chemistry, 63 4: 693-699. doi:10.1071/CH09480 84   3 Cited 3 times in Scopus3 0
Vesey, David A., Suen, Jacky Y., Seow, Vernon, Lohman, Rink-Jan, Liu, Ligong, Gobe, Glenda C., Johnson, David W. and Fairlie, David P. (2013) PAR2-induced inflammatory responses in human kidney tubular epithelial cells. American Journal of Physiology - Renal Physiology, 304 6: F737-F750. doi:10.1152/ajprenal.00540.2012 50   2 Cited 3 times in Scopus3 0
Ferro, Vito, Dredge, Keith, Liu, Ligong, Hammond, Edward, Bytheway, Ian, Li, Caiping, Johnstone, Ken, Karoli, Tomislav, Davis, Kat, Copeman, Elizabeth and Gautam, Anand: (2007) PI-88 and novel heparan sulfate mimetics inhibit angiogenesis. Seminars in Thrombosis and Hemostasis, 33 5: 557-562. doi:10.1055/s-2007-982088 95   68 Cited 73 times in Scopus73 0
Patel, Onisha, Kjer-Nielsen, Lars, Le Nours, Jerome, Eckle, Sidonia B. G., Birkinshaw, Richard, Beddoe, Travis, Corbett, Alexandra J., Liu, Ligong, Miles, John J., Meehan, Bronwyn, Reantragoon, Rangsima, Sandoval-Romero, Maria L., Sullivan, Lucy C., Brooks, Andrew G., Chen, Zhenjun, Fairlie, David P., McCluskey, James and Rossjohn, Jamie (2013) Recognition of vitamin B metabolites by mucosal-associated invariant T cells. Nature Communications, 4 2142.1-2142.8. doi:10.1038/ncomms3142 19   30 Cited 28 times in Scopus28 1
Ferro, Vito, Fairweather, Jon, Karoli, Tomislav and Liu, Ligong (2005). Sulfated oligosaccharide derivatives. WO/2005/085264. 44  
Johnstone, Ken D., Karoli, Tomislav, Liu, Ligong, Dredge, Keith, Copeman, Elizabeth, Li, Cai Ping, Davis, Kat, Hammond, Edward, Bytheway, Ian, Kostewicz, Edmund, Chiu, Francis C. K., Shackleford, David M., Charman, Susan A., Charman, William N., Harenberg, Job, Gonda, Thomas J. and Ferro, Vito (2010) Synthesis and biological evaluation of polysulfated oligosaccharide glycosides as inhibitors of angiogenesis and tumor growth. Journal of Medicinal Chemistry, 53 4: 1686-1699. doi:10.1021/jm901449m 112 76 28 Cited 29 times in Scopus29 0
Karoli, Tomislav, Liu, Ligong, Fairweather, Jon K., Hammond, Edward, Li, Cai Ping, Cochran, Siska, Bergefall, Kicki, Trybala, Edward, Addison, Russell S. and Ferro, Vito (2005) Synthesis, biological activity, and preliminary pharmacokinetic evaluation of analogues of a phosphosulfomannan angiogenesis inhibitor (PI-88). Journal of Medicinal Chemistry, 48 26: 8229-8236. doi:10.1021/jm050618p 75   43 Cited 42 times in Scopus42 0
Liu, Ligong, Li, Caiping, Cochran, Siska, Jimmink, Shane and Ferro, Vito (2012) Synthesis of a heparan sulfate mimetic library targeting FGF and VEGF via click chemistry on a monosaccharide template. ChemMedChem, 7 7: 1267-1275. doi:10.1002/cmdc.201200151 71 1 2 Cited 1 times in Scopus1 1
Fairweather, Jon K., Liu, Ligong, Karoli, Tomislav and Ferro, Vito (2012) Synthesis of disaccharides containing 6-Deoxy-α-L-talose as potential heparan sulfate mimetics. Molecules, 17 8: 9790-9802. doi:10.3390/molecules17089790 37   0 Cited 0 times in Scopus0 0
Corbett, Alexandra J., Eckle, Sidonia B. G., Birkinshaw, Richard W., Liu, Ligong, Patel, Onisha, Mahony, Jennifer, Chen, Zhenjun, Reantragoon, Rangsima, Meehan, Bronwyn, Cao, Hanwei, Williamson, Nicholas A., Strugnell, Richard A., Van Sinderen, Douwe, Mak, Jeffrey Y. W., Fairlie, David P., Kjer-Nielsen, Lars, Rossjohn, Jamie and McClusky, James (2014) T-cell activation by transitory neo-antigens derived from distinct microbial pathways. Nature, 509 7500: 361-365. doi:10.1038/nature13160 26   Cited 20 times in Scopus20 24
Fairlie, David P., Stoermer, Martin, Lucke, Andrew, Lohman, Rink-Jan, Liu, Ligong and Ruiz-Gomez, Gloria (2011). Towards orally bioavailable peptides and peptidomimetics. In: Abstracts of Papers of the American Chemical Society. 241st National Meeting and Exposition of the American-Chemical-Society (ACS), Anaheim, CA, United States, (). 27-31 March 2011. 54   0
Freeman, Craig, Liu, Ligong, Banwell, Martin G., Brown, Kathryn J., Bezos, Anna, Ferro, Vito and Parish, Christopher R. (2005) Use of Sulfated Linked Cyclitols as Heparan Sulfate Mimetics to Probe the Heparin/Heparan Sulfate Binding Specificity of Proteins. Journal of Biological Chemistry, 280 10: 8842-8849. doi:10.1074/jbc.M410769200 81   33 Cited 37 times in Scopus37 3