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Lane, Steven, Saal, Russell, Mollee, Peter, Jones, Mark, Grigg, Andrew, Taylor, Kerry, Seymour, John, Kennedy, Glen, Williams, Bronwyn, Grimmett, Karen, Griffiths, Vanessa, Gill, Devinder, Hourigan, Matthew and Marlton, Paula (2008) A 1 log rise in RQ-PCR transcript levels defines molecular relapse in core binding factor accute myeloid leukemia and predicts subsequent morphologic relapse. Leukemia & Lymphoma, 49 3: 517-523. doi:10.1080/10428190701817266 143   20 Cited 17 times in Scopus17 0
Sykes, Stephen M., Lane, Steven W., Bullinger, Lars, Kalaitzidis, Demetrios, Yusuf, Rushdia, Saez, Borja, Ferraro, Francesca, Mercier, Francois, Singh, Harshabad, Brumme, Kristina M., Acharya, Sanket S., Schoell, Claudia, Tothova, Zuzana, Attar, Eyal C., Froehling, Stefan, DePinho, Ronald A., Armstrong, Scott A., Gilliland, D. Gary and Scadden, David T. (2011) AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias. Cell, 146 5: 697-708. doi:10.1016/j.cell.2011.07.032 47   65 Cited 65 times in Scopus65 3
Lane, Steven W. (2012) Bad to the bone. Blood, 119 2: 323-325. doi:10.1182/blood-2011-10-383901 25   1 Cited 2 times in Scopus2 3
Faber, Katrin, Bullinger, Lars, Ragu, Christine, Garding, Angela, Mertens, Daniel, Miller, Christina, Martin, Daniela, Walcher, Daniel, Doehner, Konstanze, Doehner, Hartmut, Claus, Rainer, Plass, Christoph, Sykes, Stephen M., Lane, Steven W., Scholl, Claudia and Froehling, Stefan (2013) CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling. Journal of Clinical Investigation, 123 1: 299-314. doi:10.1172/JCI64745 11   6 Cited 6 times in Scopus6 13
Mullally, Ann, Lane, Steven W., Poveromo, Luke, Al-Shahrour, Fatima, Kutok, Jeffery and Ebert, Benjamin L. (2010). Characterizing the disease-initiating cell population in a murine model of Jak2V617F+ myeloproliferative neoplasm. In: Blood. 52nd Annual Meeting of the American Society of Hematology (ASH), Orlando, FL, United States, (144-145). 4-7 Dec 2010. 25   0
Housman, Elizabeth, Chang, Priscilla, Lane, Steven W., Blinder, Russell, Galinsky, Ilene, Kesari, Santosh, Ho, Vincent T., Stone, Richard M. and Mullally, Ann (2010) CNS Relapse in Acute Promyeloctyic Leukemia. Journal of Clinical Oncology, 28 24: E409-E411. doi:10.1200/JCO.2009.27.1577 40   2 Cited 3 times in Scopus3 1
Joseph, Chacko, Quach, Julie M., Walkley, Carl R., Lane, Steven W., Lo Celso, Cristina and Purton, Louise E. (2013) Deciphering hematopoietic stem cells in their niches: a critical appraisal of genetic models, lineage tracing, and imaging strategies. Cell Stem Cell, 13 5: 520-533. doi:10.1016/j.stem.2013.10.010 13   7 Cited 4 times in Scopus4 1
Mullally, Ann, Bruedigam, Claudia, Poveromo, Luke, Heidel, Florian H., Purdon, Amy, Vu, Therese, Austin, Rebecca, Heckl, Dirk, Breyfogle, Lawrence J., Kuhn, Catherine Paine, Kalaitzidis, Demetrios, Armstrong, Scott A., Williams, David A., Hill, Geoff R., Ebert, Benjamin L. and Lane, Steven W. (2013) Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-alpha in a murine model of polycythemia vera. Blood, 121 18: 3692-3702. doi:10.1182/blood-2012-05-432989 18   13 Cited 10 times in Scopus10 12
Lane, Steven W., Wang, Yingzi J., Lo Celso, Cristina, Ragu, Christine, Bullinger, Lars, Sykes, Stephen M., Ferraro, Francesca, Shterental, Sebastian, Lin, Charles P., Gilliland, D. Gary, Scadden, David T., Armstrong, Scott A. and Williams, David A. (2011) Differential niche and Wnt requirements during acute myeloid leukemia progression. Blood, 118 10: 2849-2856. doi:10.1182/blood-2011-03-345165 35   32 Cited 28 times in Scopus28 0
Mullally, Ann, Poveromo, Luke, Schneider, Rebekka K., Al-Shahrour, Fatima, Lane, Steven W. and Ebert, Benjamin L. (2012) Distinct roles for long-term hematopoietic stem cells and erythroid precursor cells in a murine model of Jak2V617F-mediated polycythemia vera. Blood, 120 1: 166-172. doi:10.1182/blood-2012-01-402396 5   11 Cited 11 times in Scopus11 0
Mullally, Ann, Poveromo, Luke, Brumme, Kristina, Al-Shahrour, Fatima, Lane, Steven W., Shih, Alan H., Aifantis, Iannis, Levine, Ross L. and Ebert, Benjamin L. (2011). Evaluating clonal dominance in a murine knock-in model of Jak2V617F MPN. In: Blood. 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego, CA, United States, (282-282). 10-13 Dec 2011. 53   0
Lane, Steven W., Marlton, Paula and Mollee, Peter N. (2006) Increased Mortality with FLA Compared with ADE Chemotherapy in High-risk AML (Letter to the Editor). Blood, 108 12: 3950-3951. doi:10.1182/blood-2006-06-032680 48   0 Cited 0 times in Scopus0 0
Lane, Steven W. and Mullally, Ann (2013) Jak2V617F myeloproliferative neoplasm stem cells and interferon-alpha. Oncotarget, 4 4: 500-501. 25   0 Cited 0 times in Scopus0
Lane, Steven W. and Gilliland, D. Gary (2010) Leukemia stem cells. Seminars in Cancer Biology, 20 2: 71-76. doi:10.1016/j.semcancer.2009.12.001 47   17 Cited 22 times in Scopus22 0
Lane, Steven W., Lo Celso, Cristina, Sykes, Stephen M., Shterental, Sebastian, Paktinat, Mahnaz, Lin, Charles P., Williams, David A., Scadden, David T. and Gilliland, D. Gary (2009). Leukemia stem cells are resistant to in vivo, cell non-autonomous Wnt inhibition.. In: Blood. 51st Annual Meeting of the American Society of Hematology, New Orleans, LA, United States, (424-424). 5-8 Dec 2009. 26   0
Kalaitzidis, Demetrios, Sykes, Stephen M., Punt, Natalie, Tang, Yuefeng, Lane, Steven W., Clish, Clary, Gilliland, D. Gary, Scadden, David T., Guertin, David and Armstrong, Scott A. (2011). Mtor complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis. In: Blood. 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego, CA, United States, (180-180). 10-13 Dec 2011. 61   0
Kharas, Michael G., Lengner, Christopher J., Al-Shahrour, Fatima, Bullinger, Lars, Ball, Brian, Zaidi, Samir, Morgan, Kelly, Tam, Winnie, Paktinat, Mahnaz, Okabe, Rachel, Gozo, Maricel, Einhorn, William, Lane, Steven W., Scholl, Claudia, Froehling, Stefan, Fleming, Mark, Ebert, Benjamin L., Gilliland, D. Gary, Jaenisch, Rudolf and Daley, George Q. (2010) Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia. Nature Medicine, 16 8: 903-908. doi:10.1038/nm.2187 39   79 Cited 84 times in Scopus84 1
Faber, Katrin, Bullinger, Lars, Garding, Angela, Mertens, Daniel, Martin, Daniela, Walcher, Daniel, Doehner, Konstanze, Doehner, Hartmut, Sykes, Stephen M., Claus, Rainer, Plass, Christoph, Lane, Steven W., Scholl, Claudia and Froehling, Stefan (2011). Myeloid leukemogenesis driven by aberrant CDX2 expression involves transcriptional repression of KLF4 and deregulated PPAR gamma signaling. In: Blood. 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego, CA, United States, (595-596). 10-13 Dec 2011. 55   0
Mullally, Ann, Lane, Steven W., Brumme, Kristina and Ebert, Benjamin L. (2012) Myeloproliferative Neoplasm Animal Models. Hematology/Oncology Clinics of North America, 26 5: 1065-1081. doi:10.1016/j.hoc.2012.07.007 3   1 Cited 1 times in Scopus1 0
Dorrance, Adrienne M., Kosoff', Rachelle, McGuinness, Meaghan, Harris, Chad, De Vita, Serena, Mathieu, Ronald, Lane, Steven W., Milsom, Michael D., Chernoff, Jonathan and Williams, David A. (2011). Pak A proteins are essential for hematopoietic stem/progenitor cell (HSC/P) engraftment through regulation of signaling pathways controlling HSC/P proliferation, survival, migration, and the actin cytoskeleton. In: Blood. 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego, CA, United States, (418-418). 10-13 Dec 2011. 56   0
Mullally, Ann, Lane, Steven W., Ball, Brian, Megerdichian, Christine, Okabe, Rachel, Al-Shahrour, Fatima, Paktinat, Mahnaz, Haydu, J. Erika, Housman, Elizabeth, Lord, Allegra M., Wernig, Gerlinde, Kharas, Michael G., Mercher, Thomas, Kutok, Jeffery L., Gilliland, D. Gary and Ebert, Benjamin L. (2010) Physiological Jak2V617F expression causes a lethal myeloproliferative neoplasm with differential effects on hematopoietis stem and progenitor cells. CANCER CELL, 17 6: 584-596. doi:10.1016/j.ccr.2010.05.015 39   88 Cited 92 times in Scopus92 1
Gill, Saar, Lane, Steven, Crawford, Julie, Cull, Gavin, Joske, David, Joske, David, Marlton, Paula, Mollee, Peter, Prince, Miles and Seymour, John (2008) Prolonged haematological toxicity from the hyper-CVAD regimen: Manifestations, frequency, and natural history in a cohort of 125 consecutive patients. Annals of Hematology, 87 9: 727-734. doi:10.1007/s00277-008-0488-6 40   6 Cited 7 times in Scopus7 0
Lane, Steven W., De Vita, Serena, Alexander, Kylie A., Karaman, Ruchan, Milsom, Michael D., Dorrance, Adrienne M., Purdon, Amy, Louis, Leeann, Bouxsein, Mary L. and Williams, David A. (2012) Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development. Blood, 119 3: 736-744. doi:10.1182/blood-2011-07-368753 25   6 Cited 6 times in Scopus6 0
Lane, Steven W., Gill, Devinder, Mollee, Peter N. and Rajkumar, S. Vincent (2005) Role of VAD in the initial treatment of multiple myeloma. Blood, 106 10: 3674-3675. doi:10.1182/blood-2005-07-2610 48   9 Cited 8 times in Scopus8 0
Lane, Steven W., Crawford, Julie, Kenealy, Melita, Cull, Gavin, Seymour, John F., Prince, H. Miles, Marlton, Paula, Gill, Devinder ‌ and Mollee, Peter‌ N. (2006) Safety and efficacy of pegfilgrastim compared to granulocyte colony stimulating factor (G-CSF)supporting a dose-intensive, rapidly cycling anti-metabolite containing chemotherapy regimen (Hyper-CVAD) for lymphoid malignancy. Leukemia and Lymphoma, 47 9: 1813-1817. doi:10.1080/10428190600632832 156   9 Cited 11 times in Scopus11 0
Lane, Steven W., Sykes, Stephen M., Al-Shahrour, Fatima, Shterental, Sebastian, Paktinat, Mahnaz, Lo Celso, Cristina, Jesneck, Jonathan L., Ebert, Benjamin L., Williams, David A. and Gilliland, D. Gary (2010) The Apcmin mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS. Blood, 115 17: 3489-3497. doi:10.1182/blood-2009-11-251728 28   36 Cited 36 times in Scopus36 0
Heidel, Florian H., Bullinger, Lars, Arreba-Tutusaus, Patricia, Wang, Zhu, Gaebel, Julia, Hirt, Carsten, Niederwieser, Dietger, Lane, Steven W., Doehner, Konstanze, Vasioukhin, Valera, Fischer, Thomas and Armstrong, Scott A. (2013) The cell fate determinant Llgl1 influences HSC fitness and prognosis in AML. Journal of Experimental Medicine, 210 1: 15-22. doi:10.1084/jem.20120596 21   5 Cited 6 times in Scopus6 9
Lane, Steven W., Scadden, David T. and Gilliland, D. Gary (2009) The leukemic stem cell niche: Current concepts and therapeutic opportunities. Blood, 114 6: 1150-1157. doi:10.1182/blood-2009-01-202606 59   155 Cited 164 times in Scopus164 0
Dorrance, Adrienne M., De Vita, Serena, Radu, Maria, Reddy, Pavankumar N. G., McGuinness, Meaghan K., Harris, Chad E., Mathieu, Ronald, Lane, Steven W., Kosoff, Rachelle, Milsom, Michael D., Chernoff, Jonathan and Williams, David A. (2013) The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment.. Blood, 121 13: 2474-2482. doi:10.1182/blood-2012-10-460709 21   8 Cited 8 times in Scopus8 0
Charmsaz, Sara, Yeadon, Trina, Lane, Steven, Miller, Kirrilee, Ting, Michael, Stringer, Brett, Cooper, Leanne and Boyd, Andrew (2012). The Role of Epha3 as a therapy target in leukaemia. In: Abstracts of the ISEH 41st Annual Scientific Meeting. 41st Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Amsterdam Netherlands, (S140-S141). 23-26 August 2012. 41   0
Coleman, Miranda A., Bridge, Jennifer A., Lane, Steven W., Dixon, Chantelle M., Hill, Geoffrey R., Wells, James W., Thomas, Ranjeny and Steptoe, Raymond J. (2013) Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy. Blood, 121 6: 1049-1058. doi:10.1182/blood-2012-06-434100 68   1 Cited 2 times in Scopus2 1
Lane, Steven, Gill, Devinder, McMillan, Nigel A. J., Saunders, Nicholas, Murphy, Rachel, Spurr, Terrence, Keane, Colm, Fan, Helen Mar and Mollee, Peter (2012) Valproic acid combined with cytosine arabinoside in elderly patients with acute myeloid leukemia has in vitro but limited clinical activity. Leukemia & Lymphoma, 53 6: 1077-1083. doi:10.3109/10428194.2011.642302 58   4 Cited 5 times in Scopus5 1
Gray, James X., McMillen, Lyle, Mollee, Peter, Paul, Sanjoy, Lane, Steven, Bird, Robert, Gill, Devinder, Saal, Russell and Marlton, Paula (2012) WT1 expression as a marker of minimal residual disease predicts outcome in acute myeloid leukemia when measured post-consolidation. Leukemia Research, 36 4: 453-458. doi:10.1016/j.leukres.2011.09.005 44   8 Cited 11 times in Scopus11 0