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Lane, Steven, Saal, Russell, Mollee, Peter, Jones, Mark, Grigg, Andrew, Taylor, Kerry, Seymour, John, Kennedy, Glen, Williams, Bronwyn, Grimmett, Karen, Griffiths, Vanessa, Gill, Devinder, Hourigan, Matthew and Marlton, Paula (2008) A 1 log rise in RQ-PCR transcript levels defines molecular relapse in core binding factor accute myeloid leukemia and predicts subsequent morphologic relapse. Leukemia & Lymphoma, 49 3: 517-523. doi:10.1080/10428190701817266 148   21 Cited 18 times in Scopus18 0
Sykes, Stephen M., Lane, Steven W., Bullinger, Lars, Kalaitzidis, Demetrios, Yusuf, Rushdia, Saez, Borja, Ferraro, Francesca, Mercier, Francois, Singh, Harshabad, Brumme, Kristina M., Acharya, Sanket S., Schoell, Claudia, Tothova, Zuzana, Attar, Eyal C., Froehling, Stefan, DePinho, Ronald A., Armstrong, Scott A., Gilliland, D. Gary and Scadden, David T. (2011) AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias. Cell, 146 5: 697-708. doi:10.1016/j.cell.2011.07.032 48   70 Cited 73 times in Scopus73 2
Lane, Steven W. (2012) Bad to the bone. Blood, 119 2: 323-325. doi:10.1182/blood-2011-10-383901 26   1 Cited 2 times in Scopus2 3
Faber, Katrin, Bullinger, Lars, Ragu, Christine, Garding, Angela, Mertens, Daniel, Miller, Christina, Martin, Daniela, Walcher, Daniel, Doehner, Konstanze, Doehner, Hartmut, Claus, Rainer, Plass, Christoph, Sykes, Stephen M., Lane, Steven W., Scholl, Claudia and Froehling, Stefan (2013) CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling. Journal of Clinical Investigation, 123 1: 299-314. doi:10.1172/JCI64745 13   7 Cited 7 times in Scopus7 13
Mullally, Ann, Lane, Steven W., Poveromo, Luke, Al-Shahrour, Fatima, Kutok, Jeffery and Ebert, Benjamin L. (2010). Characterizing the disease-initiating cell population in a murine model of Jak2V617F+ myeloproliferative neoplasm. In: Blood. 52nd Annual Meeting of the American Society of Hematology (ASH), Orlando, FL, United States, (144-145). 4-7 Dec 2010. 26   0
Housman, Elizabeth, Chang, Priscilla, Lane, Steven W., Blinder, Russell, Galinsky, Ilene, Kesari, Santosh, Ho, Vincent T., Stone, Richard M. and Mullally, Ann (2010) CNS Relapse in Acute Promyeloctyic Leukemia. Journal of Clinical Oncology, 28 24: E409-E411. doi:10.1200/JCO.2009.27.1577 40   2 Cited 3 times in Scopus3 1
Joseph, Chacko, Quach, Julie M., Walkley, Carl R., Lane, Steven W., Lo Celso, Cristina and Purton, Louise E. (2013) Deciphering hematopoietic stem cells in their niches: a critical appraisal of genetic models, lineage tracing, and imaging strategies. Cell Stem Cell, 13 5: 520-533. doi:10.1016/j.stem.2013.10.010 15   8 Cited 8 times in Scopus8 1
Mullally, Ann, Bruedigam, Claudia, Poveromo, Luke, Heidel, Florian H., Purdon, Amy, Vu, Therese, Austin, Rebecca, Heckl, Dirk, Breyfogle, Lawrence J., Kuhn, Catherine Paine, Kalaitzidis, Demetrios, Armstrong, Scott A., Williams, David A., Hill, Geoff R., Ebert, Benjamin L. and Lane, Steven W. (2013) Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-alpha in a murine model of polycythemia vera. Blood, 121 18: 3692-3702. doi:10.1182/blood-2012-05-432989 21   18 Cited 15 times in Scopus15 12
Lane, Steven W., Wang, Yingzi J., Lo Celso, Cristina, Ragu, Christine, Bullinger, Lars, Sykes, Stephen M., Ferraro, Francesca, Shterental, Sebastian, Lin, Charles P., Gilliland, D. Gary, Scadden, David T., Armstrong, Scott A. and Williams, David A. (2011) Differential niche and Wnt requirements during acute myeloid leukemia progression. Blood, 118 10: 2849-2856. doi:10.1182/blood-2011-03-345165 36   35 Cited 33 times in Scopus33 0
Mullally, Ann, Poveromo, Luke, Schneider, Rebekka K., Al-Shahrour, Fatima, Lane, Steven W. and Ebert, Benjamin L. (2012) Distinct roles for long-term hematopoietic stem cells and erythroid precursor cells in a murine model of Jak2V617F-mediated polycythemia vera. Blood, 120 1: 166-172. doi:10.1182/blood-2012-01-402396 6   14 Cited 14 times in Scopus14 0
Mullally, Ann, Poveromo, Luke, Brumme, Kristina, Al-Shahrour, Fatima, Lane, Steven W., Shih, Alan H., Aifantis, Iannis, Levine, Ross L. and Ebert, Benjamin L. (2011). Evaluating clonal dominance in a murine knock-in model of Jak2V617F MPN. In: Blood. 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego, CA, United States, (282-282). 10-13 Dec 2011. 57   0
Lane, Steven W., Marlton, Paula and Mollee, Peter N. (2006) Increased Mortality with FLA Compared with ADE Chemotherapy in High-risk AML (Letter to the Editor). Blood, 108 12: 3950-3951. doi:10.1182/blood-2006-06-032680 50   0 Cited 0 times in Scopus0 0
Bruedigam, Claudia, Bagger, Frederik Otzen, Heidel, Florian H., Kuhn, Catherine, Guignes, Solene, Song, Axia, Austin, Rebecca, Vu, Therese, Lee, Erwin M., Moore, Andrew S., Lock, Richard B., Bullinger, Lars, Hill, Geoff R. and Lane, Steven W. (2014). Inhibition of Telomerase with Imetelstat Is Detrimental to Leukemia Stem Cells in Acute Myeloid Leukemia (AML). In: Blood. , , (). . 25   0
Lane, Steven W. and Mullally, Ann (2013) Jak2V617F myeloproliferative neoplasm stem cells and interferon-alpha. Oncotarget, 4 4: 500-501. 27   0 Cited 0 times in Scopus0
Lane, Steven W. and Gilliland, D. Gary (2010) Leukemia stem cells. Seminars in Cancer Biology, 20 2: 71-76. doi:10.1016/j.semcancer.2009.12.001 48   19 Cited 22 times in Scopus22 0
Lane, Steven W., Lo Celso, Cristina, Sykes, Stephen M., Shterental, Sebastian, Paktinat, Mahnaz, Lin, Charles P., Williams, David A., Scadden, David T. and Gilliland, D. Gary (2009). Leukemia stem cells are resistant to in vivo, cell non-autonomous Wnt inhibition.. In: Blood. 51st Annual Meeting of the American Society of Hematology, New Orleans, LA, United States, (424-424). 5-8 Dec 2009. 27   0
Kalaitzidis, Demetrios, Sykes, Stephen M., Punt, Natalie, Tang, Yuefeng, Lane, Steven W., Clish, Clary, Gilliland, D. Gary, Scadden, David T., Guertin, David and Armstrong, Scott A. (2011). Mtor complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis. In: Blood. 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego, CA, United States, (180-180). 10-13 Dec 2011. 63   0
Kharas, Michael G., Lengner, Christopher J., Al-Shahrour, Fatima, Bullinger, Lars, Ball, Brian, Zaidi, Samir, Morgan, Kelly, Tam, Winnie, Paktinat, Mahnaz, Okabe, Rachel, Gozo, Maricel, Einhorn, William, Lane, Steven W., Scholl, Claudia, Froehling, Stefan, Fleming, Mark, Ebert, Benjamin L., Gilliland, D. Gary, Jaenisch, Rudolf and Daley, George Q. (2010) Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia. Nature Medicine, 16 8: 903-908. doi:10.1038/nm.2187 41   90 Cited 93 times in Scopus93 1
Faber, Katrin, Bullinger, Lars, Garding, Angela, Mertens, Daniel, Martin, Daniela, Walcher, Daniel, Doehner, Konstanze, Doehner, Hartmut, Sykes, Stephen M., Claus, Rainer, Plass, Christoph, Lane, Steven W., Scholl, Claudia and Froehling, Stefan (2011). Myeloid leukemogenesis driven by aberrant CDX2 expression involves transcriptional repression of KLF4 and deregulated PPAR gamma signaling. In: Blood. 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego, CA, United States, (595-596). 10-13 Dec 2011. 58   0
Mullally, Ann, Lane, Steven W., Brumme, Kristina and Ebert, Benjamin L. (2012) Myeloproliferative Neoplasm Animal Models. Hematology/Oncology Clinics of North America, 26 5: 1065-1081. doi:10.1016/j.hoc.2012.07.007 5   3 Cited 4 times in Scopus4 0
Dorrance, Adrienne M., Kosoff', Rachelle, McGuinness, Meaghan, Harris, Chad, De Vita, Serena, Mathieu, Ronald, Lane, Steven W., Milsom, Michael D., Chernoff, Jonathan and Williams, David A. (2011). Pak A proteins are essential for hematopoietic stem/progenitor cell (HSC/P) engraftment through regulation of signaling pathways controlling HSC/P proliferation, survival, migration, and the actin cytoskeleton. In: Blood. 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego, CA, United States, (418-418). 10-13 Dec 2011. 67   0
Mullally, Ann, Lane, Steven W., Ball, Brian, Megerdichian, Christine, Okabe, Rachel, Al-Shahrour, Fatima, Paktinat, Mahnaz, Haydu, J. Erika, Housman, Elizabeth, Lord, Allegra M., Wernig, Gerlinde, Kharas, Michael G., Mercher, Thomas, Kutok, Jeffery L., Gilliland, D. Gary and Ebert, Benjamin L. (2010) Physiological Jak2V617F expression causes a lethal myeloproliferative neoplasm with differential effects on hematopoietis stem and progenitor cells. CANCER CELL, 17 6: 584-596. doi:10.1016/j.ccr.2010.05.015 40   100 Cited 101 times in Scopus101 1
Gill, Saar, Lane, Steven, Crawford, Julie, Cull, Gavin, Joske, David, Joske, David, Marlton, Paula, Mollee, Peter, Prince, Miles and Seymour, John (2008) Prolonged haematological toxicity from the hyper-CVAD regimen: Manifestations, frequency, and natural history in a cohort of 125 consecutive patients. Annals of Hematology, 87 9: 727-734. doi:10.1007/s00277-008-0488-6 42   7 Cited 8 times in Scopus8 0
Lane, Steven W., De Vita, Serena, Alexander, Kylie A., Karaman, Ruchan, Milsom, Michael D., Dorrance, Adrienne M., Purdon, Amy, Louis, Leeann, Bouxsein, Mary L. and Williams, David A. (2012) Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development. Blood, 119 3: 736-744. doi:10.1182/blood-2011-07-368753 26   7 Cited 6 times in Scopus6 0
Lane, Steven W., Gill, Devinder, Mollee, Peter N. and Rajkumar, S. Vincent (2005) Role of VAD in the initial treatment of multiple myeloma. Blood, 106 10: 3674-3675. doi:10.1182/blood-2005-07-2610 51   9 Cited 8 times in Scopus8 0
Lane, Steven W., Crawford, Julie, Kenealy, Melita, Cull, Gavin, Seymour, John F., Prince, H. Miles, Marlton, Paula, Gill, Devinder ‌ and Mollee, Peter‌ N. (2006) Safety and efficacy of pegfilgrastim compared to granulocyte colony stimulating factor (G-CSF)supporting a dose-intensive, rapidly cycling anti-metabolite containing chemotherapy regimen (Hyper-CVAD) for lymphoid malignancy. Leukemia and Lymphoma, 47 9: 1813-1817. doi:10.1080/10428190600632832 162   10 Cited 11 times in Scopus11 0
Lane, Steven W., Sykes, Stephen M., Al-Shahrour, Fatima, Shterental, Sebastian, Paktinat, Mahnaz, Lo Celso, Cristina, Jesneck, Jonathan L., Ebert, Benjamin L., Williams, David A. and Gilliland, D. Gary (2010) The Apcmin mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS. Blood, 115 17: 3489-3497. doi:10.1182/blood-2009-11-251728 33   39 Cited 39 times in Scopus39 0
Heidel, Florian H., Bullinger, Lars, Arreba-Tutusaus, Patricia, Wang, Zhu, Gaebel, Julia, Hirt, Carsten, Niederwieser, Dietger, Lane, Steven W., Doehner, Konstanze, Vasioukhin, Valera, Fischer, Thomas and Armstrong, Scott A. (2013) The cell fate determinant Llgl1 influences HSC fitness and prognosis in AML. Journal of Experimental Medicine, 210 1: 15-22. doi:10.1084/jem.20120596 28   8 Cited 7 times in Scopus7 8
Lane, Steven W., Scadden, David T. and Gilliland, D. Gary (2009) The leukemic stem cell niche: Current concepts and therapeutic opportunities. Blood, 114 6: 1150-1157. doi:10.1182/blood-2009-01-202606 60   161 Cited 171 times in Scopus171 0
Dorrance, Adrienne M., De Vita, Serena, Radu, Maria, Reddy, Pavankumar N. G., McGuinness, Meaghan K., Harris, Chad E., Mathieu, Ronald, Lane, Steven W., Kosoff, Rachelle, Milsom, Michael D., Chernoff, Jonathan and Williams, David A. (2013) The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment.. Blood, 121 13: 2474-2482. doi:10.1182/blood-2012-10-460709 28   9 Cited 9 times in Scopus9 0
Charmsaz, Sara, Yeadon, Trina, Lane, Steven, Miller, Kirrilee, Ting, Michael, Stringer, Brett, Cooper, Leanne and Boyd, Andrew (2012). The Role of Epha3 as a therapy target in leukaemia. In: Abstracts of the ISEH 41st Annual Scientific Meeting. 41st Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Amsterdam Netherlands, (S140-S141). 23-26 August 2012. 46   0
Coleman, Miranda A., Bridge, Jennifer A., Lane, Steven W., Dixon, Chantelle M., Hill, Geoffrey R., Wells, James W., Thomas, Ranjeny and Steptoe, Raymond J. (2013) Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy. Blood, 121 6: 1049-1058. doi:10.1182/blood-2012-06-434100 71   1 Cited 2 times in Scopus2 1
Lane, Steven, Gill, Devinder, McMillan, Nigel A. J., Saunders, Nicholas, Murphy, Rachel, Spurr, Terrence, Keane, Colm, Fan, Helen Mar and Mollee, Peter (2012) Valproic acid combined with cytosine arabinoside in elderly patients with acute myeloid leukemia has in vitro but limited clinical activity. Leukemia & Lymphoma, 53 6: 1077-1083. doi:10.3109/10428194.2011.642302 80   4 Cited 5 times in Scopus5 1
Gray, James X., McMillen, Lyle, Mollee, Peter, Paul, Sanjoy, Lane, Steven, Bird, Robert, Gill, Devinder, Saal, Russell and Marlton, Paula (2012) WT1 expression as a marker of minimal residual disease predicts outcome in acute myeloid leukemia when measured post-consolidation. Leukemia Research, 36 4: 453-458. doi:10.1016/j.leukres.2011.09.005 48   9 Cited 11 times in Scopus11 0