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Richardson, Des R., Kalinowski, Danuta S., Richardson, Vera, Sharpe, Philip C., Lovejoy, David B., Islam, Mohammad and Bernhardt, Paul V. (2009) 2-acetylpyridine thiosemicarbazones are potent iron chelators and antiproliferative agents: Redox activity, iron complexation and characterization of their antitumor activity. Journal of Medicinal Chemistry, 52 5: 1459-1470. doi:10.1021/jm801585u 121   69 Cited 72 times in Scopus72 0
Stefani, Christian, Jansson, Patric J., Gutierrez, Elaine, Bernhardt, Paul V., Richardson, Des R. and Kalinowski, Danuta S. (2013) Alkyl substituted 2′-benzoylpyridine thiosemicarbazone chelators with potent and selective anti-neoplastic activity: novel ligands that limit methemoglobin formation. Journal of Medicinal Chemistry, 56 1: 357-370. doi:10.1021/jm301691s 50   3 Cited 5 times in Scopus5 0
Stefani, Christian, Punnia-Moorthy, Gaya, Lovejoy, David B., Jansson, Patric J., Kalinowski, Danuta S., Sharpe, Philip C., Bernhardt, Paul V. and Richardson, Des R. (2011) Halogenated 2′-benzoylpyridine thiosemicarbazone (XBpT) chelators with potent and selective anti-neoplastic activity: Relationship to intracellular redox activity. Journal of Medicinal Chemistry, 54 19: 6936-6948. doi:10.1021/jm200924c 58   11 Cited 10 times in Scopus10 0
Basha, Maram T., Chartres, Jy D., Pantarat, Namfon, Ali, Mohammad Akbar, Mirza, Aminul Huq, Kalinowski, Danuta S., Richardson, Des R. and Bernhardt, Paul V. (2012) Heterocyclic dithiocarbazate iron chelators: Fe coordination chemistry and biological activity. Dalton Transactions, 41 21: 6536-6548. doi:10.1039/c2dt12387h 93   10 Cited 9 times in Scopus9 1
Bernhardt, Paul V., Sharpe, Philip C., Islam, Mohammed, Lovejoy, David B., Kalinowski, Danuta S. and Richardson, Des R. (2009) Iron chelators of the dipyridylketone thiosemicarbazone class: Precomplexation and transmetalation effects on anticancer activity. Journal of Medicinal Chemistry, 52 2: 407-415. doi:10.1021/jm801012z 89   2 Cited 56 times in Scopus56 0
Quach, Patricia, Gutierrez, Elaine, Basha, Maram Talal, Kalinowski, Danuta S., Sharpe, Philip C., Lovejoy, David B., Bernhardt, Paul V., Jansson, Patric J. and Richardson, Des R. (2012) Methemoglobin formation by triapine, di-2-pyridylketone-4,4-dimethyl-3- thiosemicarbazone (Dp44mT), and other anticancer thiosemicarbazones: identification of novel thiosemicarbazones and therapeutics that prevent this effect. Molecular Pharmacology, 82 1: 105-114. doi:10.1124/mol.112.078964 30   12 Cited 14 times in Scopus14 0
Lovejoy, David B., Sharp, Danae M., Seebacher, Nicole, Obeidy, Peyman, Prichard, Thomas, Stefani, Christian, Basha, Maram T., Sharpe, Philip C., Jansson, Patric J., Kalinowski, Danuta S., Bernhardt, Paul V. and Richardson, Des R. (2012) Novel second-generation Di-2-Pyridylketone Thiosemicarbazones show synergism with standard chemotherapeutics and demonstrate potent activity against lung cancer xenografts after oral and intravenous administration in vivo. Journal of Medicinal Chemistry, 55 16: 7230-7244. doi:10.1021/jm300768u 75   25 Cited 25 times in Scopus25 0
Kalinowski, Danuta S., Sharpe, Philip C., Bernhardt, Paul V. and Richardson, Des R. (2008) Structure-activity relationships of novel iron chelators for the treatment of iron overload disease: The methyl pyrazinylketone isonicotinoyl hydrazone series. Journal of Medicinal Chemistry, 51 2: 331-344. doi:10.1021/jm7012562 88   44 Cited 48 times in Scopus48 0
Sharpe, Philip C., Richardson, Des R., Kalinowski, Danuta S. and Bernhardt, Paul V. (2011) Synthetic and natural products as iron chelators. Current Topics in Medicinal Chemistry, 11 5: 591-607. doi:10.2174/156802611794785163 76 1 9 Cited 9 times in Scopus9 0
Kovacevic, Zaklina, Kalinowski, Danuta S., Lovejoy, David B., Yu, Yu, Rahmanto, Yohan Suryo, Sharpe, Phillip C., Bernhardt, Paul V. and Richardson, Des R. (2011) The medicinal chemistry of novel iron chelators for the treatment of cancer. Current Topics in Medicinal Chemistry, 11 5: 483-499. doi:10.2174/156802611794785190 66 1 30 Cited 31 times in Scopus31 0
Yu, Yu, Kalinowski, Danuta S., Kovacevic, Zaklina, Siafakas, Aritee R., Jansson, Patric J., Stefani, Christian, Lovejoy, David B., Sharpe, Philip C., Bernhardt, Paul V. and Richardson, Des R. (2009) Thiosemicarbazones from the old to new: Iron chelators that are more than just ribonucleotide reductase inhibitors. Journal of Medicinal Chemistry, 52 17: 5271-5294. doi:10.1021/jm900552r 71   107 Cited 107 times in Scopus107 0