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Lim, Yun-An, Rhein, Virginie, Baysang, Ginette, Meier, Fides, Poljak, Anne, Raftery, Mark J., Guilhaus, Michael, Ittner, Lars M., Eckert, Anne and Gotz, Jürgen (2010) Aβ and human amylin share a common toxicity pathway via mitochondrial dysfunction. Proteomics, 10 8: 1621-1633. doi:10.1002/pmic.200900651 8   44 Cited 45 times in Scopus45 0
Goetz, Juergen, Ittner, Lars M. and Schonrock, Nicole (2006) Alzheimer's disease and frontotemporal dementia: prospects of a tailored therapy?. Medical Journal of Australia, 185 7: 381-384. 14   18
Goetz, Juergen, Matamales, Miriam, Goetz, Naeman N., Ittner, Lars M. and Eckert, Anne (2012) Alzheimer's disease models and functional genomics-how many needles are there in the haystack?. Frontiers in Physiology, 3 320: 320.1-320.14. doi:10.3389/fphys.2012.00320 56   Cited 2 times in Scopus2 3
Gotz, Jurgen, Schonrock, Nicole, Vissel, Bryce and Ittner, Lars M. (2009) Alzheimer's disease selective vulnerability and modeling in transgenic Mice. Journal of Alzheimer's Disease, 18 2: 243-251. doi:10.3233/JAD-2009-1143 15   14 Cited 14 times in Scopus14 0
Ittner, Lars M. and Gotz, Jürgen (2011) Amyloid-β and tau - A toxic pas de deux in Alzheimer's disease. Nature Reviews Neuroscience, 12 2: 67-72. doi:10.1038/nrn2967 17   231 Cited 215 times in Scopus215 0
Rhein, Virginie, Song, Xiaomin, Wiesner, Andreas, Ittner, Lars M., Baysang, Ginette, Meier, Fides, Ozmen, Laurence, Bluethmann, Horst, Drose, Stefan, Brandt, Ulrich, Savaskan, Egemen, Czech, Christian, Gotz, Jurgen and Eckert, Anne (2009) Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice. Proceedings of the National Academy of Sciences of the United States of America, 106 47: 20057-20062. doi:10.1073/pnas.0905529106 18   179 Cited 189 times in Scopus189 1
Gotz, Jurgen and Ittner, Lars M. (2008) Animal models of Alzheimer's disease and frontotemporal dementia. Nature Reviews Neuroscience, 9 7: 532-544. doi:10.1038/nrn2420 30   243 Cited 278 times in Scopus278 0
Gotz, Jurgen, Gladbach, Amadeus, Pennanen, Luis, van Eersel, Janet, Schild, Andreas, David, Della and Ittner, Lars M. (2010) Animal models reveal role for tau phosphorylation in human disease. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1802 10: 860-871. doi:10.1016/j.bbadis.2009.09.008 18   25 Cited 24 times in Scopus24 0
Götz, Jurgen, Ittner, Lars M, Schonrock, Nicole and Cappai, Roberto (2008) An update on the toxicity of A-beta in Alzheimer's disease. Neuropsychiatric Disease and Treatment, 4 6: 1033-1042. doi:10.2147/NDT.S3016 14   Cited 21 times in Scopus21 0
Ittner, Arne, Ke, Yazi D., van Eersel, Janet, Gladbach, Amadeus, Gotz, Jurgen and Ittner, Lars M. (2011) Brief update on different roles of tau in neurodegeneration. IUBMB Life, 63 7: 495-502. doi:10.1002/iub.467 11   12 Cited 16 times in Scopus16 0
van Eersel, Janet, Ke, Yazi D., Gladbach, Amadeus, Bi, Mian, Gotz, Jurgen, Kril, Jillian J. and Ittner, Lars M. (2011) Cytoplasmic accumulation and aggregation of TDP-43 upon proteasome inhibition in cultured neurons. PLoS ONE, 6 7: e22850.1-e22850.13. doi:10.1371/journal.pone.0022850 9   19 Cited 19 times in Scopus19 1
Ittner, Lars M., Ke, Yazi D., Delerue, Fabien, Bi, Mian, Gladbach, Amadeus, van Eersel, Janet, Wolfing, Heidrun, Chieng, Billy C., Christie, MacDonald J., Napier, Ian A., Eckert, Anne, Staufenbiel, Matthias, Hardeman, Edna and Gotz, Jurgen (2010) Dendritic function of tau mediates amyloid-β toxicity in Alzheimer's disease mouse models. Cell, 142 3: 387-397. doi:10.1016/j.cell.2010.06.036 18   346 Cited 382 times in Scopus382 1
Gotz, Jurgen, Lim, Yun-An, Ke, Yazi D., Eckert, Anne and Ittner, Lars M. (2010) Dissecting Toxicity of Tau and β-Amyloid. Neurodegenerative Diseases, 7 1-3: 10-12. doi:10.1159/000283475 20   10 Cited 32 times in Scopus32 0
Deters, Natasha, Ittner, Lars M. and Gotz, Jurgen (2008) Divergent phosphorylation pattern of tau in P301L tau transgenic mice. European Journal of Neuroscience, 28 1: 137-147. doi:10.1111/j.1460-9568.2008.06318.x 10   31 Cited 35 times in Scopus35 0
Götz, Jürgen, Ittner, Lars M. and Kins, Stefan (2006) Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?. Journal of Neurochemistry, 98 4: 993-1006. doi:10.1111/j.1471-4159.2006.03955.x 46   66 Cited 68 times in Scopus68 0
Liu, Xin, Dobbie, Michael, Tunningley, Rob, Whittle, Belinda, Zhang, Yafei, Ittner, Lars M. and Gotz, Jurgen (2011) ENU mutagenesis screen to establish motor phenotypes in wild-type mice and modifiers of a pre-existing motor phenotype in tau mutant mice. Journal of Biomedicine and Biotechnology, 2011 130947.1-130947.11. doi:10.1155/2011/130947 11   2 Cited 3 times in Scopus3 0
Ke, Yazi D., Delerue, Fabien, Gladbach, Amadeus, Gotz, Jurgen and Ittner, Lars M. (2009) Experimental diabetes mellitus exacerbates Tau pathology in a transgenic mouse model of Alzheimer's disease. PLoS ONE, 4 11: e7917.1-e7917.7. doi:10.1371/journal.pone.0007917 10   54 Cited 58 times in Scopus58 1
Krupka, Niklas, Strappe, Padraig, Gotz, Jürgen and Ittner, Lars M. (2010) Gateway-compatible lentiviral transfer vectors for ubiquitin promoter driven expression of fluorescent fusion proteins. Plasmid, 63 3: 155-160. doi:10.1016/j.plasmid.2010.01.002 15   4 Cited 4 times in Scopus4 0
Nilsen, Linn Hege, Rae, Caroline, Ittner, Lars M., Goetz, Juergen and Sonnewald, Ursula (2013) Glutamate metabolism is impaired in transgenic mice with tau hyperphosphorylation. Journal of Cerebral Blood Flow and Metabolism, 33 5: 684-691. doi:10.1038/jcbfm.2012.212 27   7 Cited 6 times in Scopus6 1
Lim, Yun-An, Ittner, Lars M., Lim, Yun Li and Gotz, Jürgen (2008) Human but not rat amylin shares neurotoxic properties with Aβ42 in long-term hippocampal and cortical cultures. FEBS Letters, 582 15: 2188-2194. doi:10.1016/j.febslet.2008.05.006 10   30 Cited 31 times in Scopus31 0
Lim, Yun-An, Grimm, Amandine, Giese, Maria, Mensah-Nyagan, Ayikoe Guy, Villafranca, J. Ernest, Ittner, Lars M., Eckert, Anne and Gotz, Jurgen (2011) Inhibition of the mitochondrial enzyme ABAD restores the amyloid-β-mediated deregulation of estradiol. PLoS ONE, 6 12: e28887.1-e28887.12. doi:10.1371/journal.pone.0028887 13   8 Cited 9 times in Scopus9 0
Goetz, Juergen, Ittner, Lars M., Goetz, Naeman N., Lam, Hong and Nicholas, Hannah R. (2011) Invertebrate and Vertebrate Models of Tauopathies. Animal Models for Neurodegenerative Disease, 6: 69-85. doi:10.1039/9781849732758 5   0 0
Goetz, Juergen, Ittner, Lars M., Faendrich, Marcus and Schonrock, Nicole (2008) Is tau aggregation toxic or protective: a sensible question in the absence of sensitive methods?. Journal of Alzheimers Disease, 14 4: 423-429. 14   15 Cited 20 times in Scopus20
Schonrock, Nicole, Matamales, Miriam, Ittner, Lars M. and Gotz, Juergen (2012) MicroRNA networks surrounding APP and amyloid-β metabolism - implications for Alzheimer's disease. Experimental Neurology, 235 2: 447-454. doi:10.1016/j.expneurol.2011.11.013 16 20 21 Cited 22 times in Scopus22 0
Gotz, Jurgen, Eckert, Anne, Matamales, Miriam, Ittner, Lars M. and Liu, Xin (2011) Modes of Aβ toxicity in Alzheimer's disease. Cellular and Molecular Life Sciences, 68 20: 3359-3375. doi:10.1007/s00018-011-0750-2 15   28 Cited 34 times in Scopus34 0
Schonrock, Nicole, Ke, Yazi D., Humphreys, David, Staufenbiel, Matthias, Ittner, Lars M., Preiss, Thomas and Gotz, Jurgen (2010) Neuronal microrna deregulation in response to Alzheimer's disease amyloid-β. PLoS ONE, 5 6: e11070.1-e11070.11. doi:10.1371/journal.pone.0011070 9   58 Cited 71 times in Scopus71 0
Ittner, Lars M., Fath, Thomas, Ke, Yazi D., Bi, Mian, van Eersel, Janet, Li, Kong M., Gunning, Peter and Gotz, Jurgen (2008) Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia. Proceedings of the National Academy of Sciences of the United States of America, 105 41: 15997-16002. doi:10.1073/pnas.0808084105 11   72 Cited 83 times in Scopus83 0
Ittner, Lars M., Ke, Yazi D. and Gotz, Jurgen (2009) Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease. Journal of Biological Chemistry, 284 31: 20909-20916. doi:10.1074/jbc.M109.014472 9   50 Cited 75 times in Scopus75 0
van Eersel, Janet, Bi, Mian, Ke, Yazi D., Hodges, John R., Xuereb, John H., Gregory, Gillian C., Halliday, Glenda M., Gotz, Jurgen, Kril, Jillian J. and Ittner, Lars M. (2009) Phosphorylation of soluble tau differs in Pick's disease and Alzheimer's disease brains. Journal of Neural Transmission, 116 10: 1243-1251. doi:10.1007/s00702-009-0293-y 9   14 Cited 17 times in Scopus17 0
Fath, Thomas, Ke, Yazi D., Gunning, Peter, Gotz, Jürgen and Ittner, Lars M. (2009) Primary support cultures of hippocampal and substantia nigra neurons. Nature Protocols, 4 1: 78-85. doi:10.1038/nprot.2008.199 17   39 Cited 42 times in Scopus42 0
Götz, Jürgen, Ittner, Lars M. and David, Della C. (2005) Role of the protein tau in Alzheimer's disease. Drug Discovery Today: Disease Mechanisms, 2 4: 395-400. doi:10.1016/j.ddmec.2005.11.008 9   Cited 1 times in Scopus1 0
van Eersel, Janet, Ke, Yazi D., Liu, Xin, Delerue, Fabien, Kril, Jillian J., Gotz, Jürgen and Ittner, Lars M. (2010) Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models. Proceedings of the National Academy of Sciences of the United States of America, 107 31: 13888-13893. doi:10.1073/pnas.1009038107 11   59 Cited 69 times in Scopus69 1
Deters, Natasha, Ittner, Lars M. and Gotz, Jurgen (2009) Substrate-specific reduction of PP2A activity exaggerates tau pathology. Biochemical and Biophysical Research Communications, 379 2: 400-405. doi:10.1016/j.bbrc.2008.12.140 7   26 Cited 25 times in Scopus25 0
Nisbet, Rebecca M., Polanco, Juan-Carlos, Ittner, Lars M. and Gotz, Jurgen (2014) Tau aggregation and its interplay with amyloid-β. Acta Neuropathologica, . doi:10.1007/s00401-014-1371-2 7   Cited 0 times in Scopus0 1
Ke, Yazi, Dramiga, Joe, Schütz, Ulrich, Kril, Jillian J., Ittner, Lars M., Schröder, Hannsjörg and Götz, Jürgen (2012) Tau-mediated nuclear depletion and cytoplasmic accumulation of SFPQ in Alzheimer's and Pick's disease. PloS One, 7 4: 1-8. doi:10.1371/journal.pone.0035678 19   11 Cited 17 times in Scopus17 6
Bi, Mian, Ittner, Arne, Ke, Yazi D., Gotz, Jurgen and Ittner, Lars M. (2011) Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic mice. PLoS ONE, 6 12: e26860.1-e26860.7. doi:10.1371/journal.pone.0026860 17   41 Cited 41 times in Scopus41 3
Gotz, Jurgen, Ittner, Arne and Ittner, Lars M. (2012) Tau-targeted treatment strategies in Alzheimer's disease. British Journal of Pharmacology, 165 5: 1246-1259. doi:10.1111/j.1476-5381.2011.01713.x 18   28 Cited 27 times in Scopus27 0
Ittner, Arne, Bertz, Josefine, Suh, Lisa S., Stevens, Claire H., Gotz, Jurgen and Ittner, Lars M. (2014) Tau-targeting passive immunization modulates aspects of pathology in tau transgenic mice. Journal of Neurochemistry, 1-11. doi:10.1111/jnc.12821 9   Cited 0 times in Scopus0 1
Ittner, Lars M., Schwerdtfeger, Kerstin, Kunz, Thomas H., Muff, Roman, Husmann, Knut, Grimm, Christian, Hafezi, Farhad, Langh, Karl S., Kurrer, Michael O., Gotz, Jurgen, Born, Walter and Fischer, Jan A. (2008) Transgenic mice with ocular overexpression of an adrenomedullin receptor reflect human acute angle-closure glaucoma. Clinical Science, 114 1-2: 49-58. doi:10.1042/CS20070163 8   7 Cited 7 times in Scopus7 0