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Rowlinson, Scott W., Yoshizato, Hideo, Barclay, Johanna L., Brooks, Andrew J., Behncken, Stuart N., Kerr, Linda M., Millard, Kirstin, Palethorpe, Kathryn, Nielsen, Katherine, Clyde-Smith, Jodie, Hancock, John F. and Waters, Michael J. (2008) An agonist-induced conformational change in the growth hormone receptor determines the choice of signalling pathway. Nature Cell Biology, 10 6: 740-747. doi:10.1038/ncb1737 107   37 Cited 44 times in Scopus44 0
Crouthamel, Marykate, Abankwa, Daniel, Zhang, Li, DiLizio, Cherisse, Manning, David R., Hancock, John F. and Wedegaertner, Philip B. (2010) An N-terminal polybasic motif of G alpha(q) is required for signaling and influences membrane nanodomain distribution. Molecular Pharmacology, 78 4: 767-777. doi:10.1124/mol.110.066340 63   3 Cited 3 times in Scopus3 0
Abankwa, Daniel, Hanzal-Bayer, Michael, Ariotti, Nicolas, Plowman, Sarah J., Gorfe, Alemayehu A, Parton, Robert G., McCammon, J. Andrew and Hancock, John F. (2008) A novel switch region regulated H-ras membrane orientation and signal output. The EMBO journal, 27 5: 727-735. doi:10.1038/emboj.2008.10 77   76 Cited 80 times in Scopus80 0
Ariotti, Nicholas, Fernández-Rojo, Manuel, Zhou, Yong, Hill, Michelle M., Rodkey, Travis L., Inder, Kerry L., Tanner, Lukas B., Wenk, Markus R., Hancock, John F. and Parton, Robert G. (2014) Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling. Journal of Cell Biology, 204 5: 777-792. doi:10.1083/jcb.201307055 41   10 Cited 13 times in Scopus13 1
Fernández Rojo, Manuel, Gongora, Milena, Fitzsimmons, Rebecca L., Martel, Nick, Martin, Sheree D., Nixon, Susan, Brooks, Andrew J., Ikonomopoulou, Maria P., Martin, Sally, Lo, Harriet P., Myers, Stephen A., Restall, Christina, Ferguson, Charles, Pilch, Paul F., McGee, Sean L., Anderson, Robin L., Waters, Michael J., Hancock, John F., Grimmond, Sean M., Muscat, George E. and Parton, Robert G. (2013) Caveolin-1 is necessary for hepatic oxidative lipid metabolism: evidence for crosstalk between caveolin-1 and bile acid signaling. Cell Reports, 4 2: 238-247. doi:10.1016/j.celrep.2013.06.017 65   6 Cited 6 times in Scopus6 2
Chadda, Rahul, Howes, Mark T., Plowman, Sarah J., Hancock, John F., Parton, Robert G. and Mayor, Satyajit (2007) Cholesterol-Sensitive Cdc42 Activation Regulates Actin Polymerization for Endocytosis via the GEEC Pathway. Traffic, 8 6: 702-717. doi:10.1111/j.1600-0854.2007.00565.x 92   86 Cited 83 times in Scopus83 0
Howes, Mark T., Kirkham, Matthew, Riches, James, Cortese, Katia, Walser, Piers J., Simpson, Fiona, Hill, Michelle M., Jones, Alun, Lundmark, Richard, Lindsay, Margaret R., Hernandez-Deviez, Delia J., Hadzic, Gordana, McCluskey, Adam, Bashir, Rumasia, Liu, Libin, Pilch, Paul, McMahon, Harvey, Robinson, Phillip J., Hancock, John F., Mayor, Satyajit and Parton, Robert G. (2010) Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells. Journal of Cell Biology, 190 4: 675-691. doi:10.1083/jcb.201002119 115   86 Cited 89 times in Scopus89 1
Walser, Piers, Ariotti, Nicholas, Howes, Mark, Ferguson, Charles, Webb, Richard, Schwudke, Dominik, Leneva, Natalya, Cho, Kwang-Jin, Cooper, Leanne, Rae, James, Floetenmeyer, Matthias, Oorschot, Viola M. J., Skoglund, Ulf, Simons, Kai, Hancock, John F. and Parton, Robert G. (2012) Constitutive formation of caveolae in a bacterium. Cell, 150 4: 752-763. doi:10.1016/j.cell.2012.06.042 84   17 Cited 18 times in Scopus18 13
Hill, Michelle M., Daud, Noor Huda, Aung, Cho Sanda, Loo, Dorothy, Martin, Sally, Murphy, Samantha, Black, Debra M., Barry, Rachael, Simpson, Fiona, Liu, Libin, Pilch, Paul F, Hancock, John F., Marie-Odile Parat and Parton, Robert G. (2012) Co-regulation of cell polarization and migration by caveolar proteins PTRF/cavin-1 and caveolin-1. PLoS One, 7 8: e43041.1-e43041.9. doi:10.1371/journal.pone.0043041 130 1 13 Cited 13 times in Scopus13 1
Ariotti, Nicholas, Liang, Hong, Xu, Yufei, Zhang, Yueqiang, Yonekubo, Yoshiya, Inder, Kerry, Du, Guangwei, Parton, Robert G., Hancock, John F. and Plowman, Sarah J. (2010) Epidermal growth factor receptor activation remodels the plasma membrane lipid environment to induce nanocluster formation. Molecular and Cellular Biology, 30 15: 3795-3804. doi:10.1128/MCB.01615-09 66   30 Cited 32 times in Scopus32 0
Kirkham, Matthew, Nixon, Susan J., Howes, Mark T., Abi-Rached, Laurent, Wakeham, Diane E., Hanzal-Bayer, Michael, Ferguson, Charles, Hill, Michelle M., Fernandez-Rojo, Manuel, Brown, Deborah A., Hancock, John F., Brodsky, Frances M. and Parton, Robert G. (2008) Evolutionary analysis and molecular dissection of caveola biogenesis. Journal of Cell Science, 121 12: 2075-2086. doi:10.1242/jcs.024588 53   43 Cited 47 times in Scopus47 0
van der Hoeven, Dharini, Cho, Kwang-jin, Ma, Xiaoping, Chigurupati, Sravanthi, Parton, Robert G. and Hancock, John F. (2013) Fendiline inhibits K-Ras plasma membrane localization and blocks K-Ras signal transmission. Molecular and Cellular Biology, 33 2: 237-251. doi:10.1128/MCB.00884-12 34   16 Cited 16 times in Scopus16 1
Prior, Ian A., Harding, Angus, Yan, Jun, Sluimer, Judith, Parton, Robert G. and Hancock, John F. (2001) GTP-dependent segregation of H-ras from lipid rafts is required for biological activity. Nature Cell Biology, 3 4: 368-375. doi:10.1038/35070050 75   341 Cited 346 times in Scopus346 0
Payne, Elizabeth, Bowles, Mark R., Don, Alistair, Hancock, John F. and McMillan, Nigel A. J. (2001) Human papillomavirus type 6b virus-like particles are able to activate the Ras-MAP kinase pathway and induce cell proliferation. Journal of Virology, 75 9: 4150-4157. doi:10.1128/JVI.75.9.4150-4157.2001 36   22 Cited 25 times in Scopus25 0
Nicolau, Dan V. (Jnr), Burrage, Kevin, Parton, Robert G. and Hancock, John F. (2006) Identifying optimal lipid raft characteristics required to promote nanoscale protein-protein interactions on the plasma membrane. Molecular and Cellular Biology, 26 1: 313-323. doi:10.1128/MCB.26.1.313-323.2006 63   102 Cited 106 times in Scopus106 1
Hancock, John F. (2006) Lipid rafts: contentious only from simplistic standpoints. Nature Reviews Molecular Cell Biology, 7 6: 456-462. doi:10.1038/nrm1925 72   474 Cited 484 times in Scopus484 0
Tian, Tianhai, Plowman, Sarah J., Parton, Robert G., Kloog, Yoel and Hancock, John F. (2010) Mathematical modeling of K-Ras nanocluster formation on the plasma membrane. Biophysical Journal, 99 2: 534-543. doi:10.1016/j.bpj.2010.04.055 49   17 Cited 17 times in Scopus17 0
Wilkins, Simon J., Yoong, Simon, Verkade, Heather, Mizoguchi, Takamasa, Plowman, Sarah J., Hancock, John F., Kikuchi, Yutaka, Heath, Joan K. and Perkins, Andrew C. (2008) Mtx2 directs zebrafish morphogenetic movements during epiboly by regulating microfilament formation. Developmental Biology, 314 1: 12-22. doi:10.1016/j.ydbio.2007.10.050 67   18 Cited 19 times in Scopus19 0
Inder, Kerry L., Hill, Michelle M. and Hancock, John F. (2010) Nucleophosmin and nucleolin regulate K-Ras signaling. Communicative and Integrative Biology, 3 2: 188-190. doi:10.4161/cib.3.2.10923 41 38 Cited 3 times in Scopus3 0
Hancock, John F. (2007) PA promoted to manager. Nature Cell Biology, 9 6: 615-617. doi:10.1038/ncb0607-615 38   23 Cited 24 times in Scopus24 0
Jaumot, Montserrat and Hancock, John F. (2001) Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions. Oncogene, 20 30: 3949-3958. doi:10.1038/sj.onc.1204526 45   102 Cited 110 times in Scopus110 0
Salim, Angela A., Cho, Kwang-Jin, Tan, Lingxiao, Quezada, Michelle, Lacey, Ernest, Hancock, John F. and Capon, Robert J. (2014) Rare Streptomyces N-formyl amino-salicylamides inhibit oncogenic K-Ras. Organic Letters, 16 19: 5036-5039. doi:10.1021/ol502376e 29   0 Cited 0 times in Scopus0 5
Salim, Angela A., Xiao, Xue, Cho, Kwang-Jin, Piggott, Andrew M., Lacey, Ernest, Hancock, John F. and Capon, Robert J. (2014) Rare Streptomyces sp. polyketides as modulators of K-Ras localisation. Organic and Biomolecular Chemistry, 12 27: 4872-4878. doi:10.1039/c4ob00745j 29   1 Cited 1 times in Scopus1 0
Abankwa, Daniel, Gorfe, Alemayehu A., Inder, Kerry and Hancock, John F. (2010) Ras membrane orientation and nanodomain localization generate isoform diversity. Proceedings of the National Academy of Sciences of the United States of America, 107 3: 1130-1135. doi:10.1073/pnas.0903907107 42   45 Cited 51 times in Scopus51 0
Abankwa, D, Gorfe, A.A and Hancock, John F. (2007) Ras nanoclusters: Molecular structure and assembly. Seminars in Cell and Developmental Bioloby, 18 5: 599-607. doi:10.1016/j.semcdb.2007.08.003 58   48 Cited 52 times in Scopus52 0
Hancock, John F. (2003) Ras proteins: Different signals from different locations. Nature Reviews Molecular Cell Biology, 4 5: 373-384. doi:10.1038/nrm1105 71   431 Cited 442 times in Scopus442 0
Hill, Michelle M., Scherbakov, Nadja, Schiefermeier, Natalia, Baran, JoAnne, Hancock, John F., Huber, Lukas A., Parton, Robert G. and Parat, Marie-Odile (2007) Reassessing the Role of Phosphocaveolin-1 in Cell Adhesion and Migration. Traffic, 8 12: 1695-1705. doi:10.1111/j.1600-0854.2007.00653.x 93   23 Cited 22 times in Scopus22 0
Zhou, Yong, Liang, Hong, Rodkey, Travis, Ariotti, Nicholas, Parton, Robert G. and Hancock, John F. (2013) Signal integration by lipid-mediated spatial cross talk between Ras nanoclusters. Molecular and Cellular Biology, 34 5: 862-876. doi:10.1128/MCB.01227-13 29   5 Cited 6 times in Scopus6 0
Gambin, Yann, Ariotti, Nicholas, McMahon, Kerrie-Ann, Bastiani, Michele, Sierecki, Emma, Kovtun, Oleksiy, Polinkovsky, Mark E., Magenau, Astrid, Jung, WooRam, Okano, Satomi, Zhou, Yong, Leneva, Natalya, Mureev, Sergey, Johnston, Wayne, Gaus, Katharina, Hancock, John F., Collins, Brett M., Alexandrov, Kirill and Parton, Robert G. (2014) Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae. eLIFE, e01434.1-e01434.18. doi:10.7554/eLife.01434 95 2 15
Nicolau Jr, D V, Hancock, John F. and Burrage, Kevin (2007) Sources of Anomalous Diffusion on Cell Membranes: A Monte Carlo Study. Biophysical journal, 92 6: 1975-1987. doi:10.1529/biophysj.105.076869 68   57 Cited 56 times in Scopus56 0
Cho, Kwang-jin, Park, Jin-Hee, Piggott, Andrew M., Salim, Angela A., Gorfe, Alemaheyu A., Parton, Robert G., Capon, Robert J., Lacey, Ernest and Hancock, John F. (2012) Staurosporines disrupt phosphatidylserine trafficking and mislocalize ras proteins. Journal of Biological Chemistry, 287 52: 43573-43584. doi:10.1074/jbc.M112.424457 69   19 Cited 20 times in Scopus20 3
Collins, Brett, Davis, Melissa, Hancock, John F. and Parton, Robert G. (2012) Structure-based reassessment of the caveolin signalling model: Do caveolae regulate signaling through caveolin-protein interactions. Developmental Cell, 23 1: 11-20. doi:10.1016/j.devcel.2012.06.012 50   26 Cited 27 times in Scopus27 0
Sykes, Alex M., Palstra, Nick, Abankwa, Daniel, Hill, Justine M., Skeldal, Sune, Matusica, Dusan, Venkatraman, Prahatha, Hancock, John F. and Coulson, Elizabeth J. (2012) The effects of transmembrane sequence and dimerization on cleavage of the p75 neurotrophin receptor by γ-secretase. Journal of Biological Chemistry, 287 52: 43810-43824. doi:10.1074/jbc.M112.382903 62   9 Cited 8 times in Scopus8 0
Cho, Kwang-jin, Hill, Michelle M., Chigurupati, Sravanthi, Du, Guangwei, Parton, Robert G. and Hancock, John F. (2011) Therapeutic levels of the hydroxmethylglutaryl-coenzyme A reductase inhibitor lovastatin activate Ras signaling via phospholipase D2. Molecular and Cellular Biology, 31 6: 1110-1120. doi:10.1128/MCB.00989-10 70   9 Cited 10 times in Scopus10 0