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Rowlinson, Scott W., Yoshizato, Hideo, Barclay, Johanna L., Brooks, Andrew J., Behncken, Stuart N., Kerr, Linda M., Millard, Kirstin, Palethorpe, Kathryn, Nielsen, Katherine, Clyde-Smith, Jodie, Hancock, John F. and Waters, Michael J. (2008) An agonist-induced conformational change in the growth hormone receptor determines the choice of signalling pathway. Nature Cell Biology, 10 6: 740-747. doi:10.1038/ncb1737 97   34 Cited 42 times in Scopus42 0
Crouthamel, Marykate, Abankwa, Daniel, Zhang, Li, DiLizio, Cherisse, Manning, David R., Hancock, John F. and Wedegaertner, Philip B. (2010) An N-terminal polybasic motif of G alpha(q) is required for signaling and influences membrane nanodomain distribution. Molecular Pharmacology, 78 4: 767-777. doi:10.1124/mol.110.066340 62   3 Cited 3 times in Scopus3 0
Abankwa, Daniel, Hanzal-Bayer, Michael, Ariotti, Nicolas, Plowman, Sarah J., Gorfe, Alemayehu A, Parton, Robert G., McCammon, J. Andrew and Hancock, John F. (2008) A novel switch region regulated H-ras membrane orientation and signal output. The EMBO journal, 27 5: 727-735. doi:10.1038/emboj.2008.10 76   71 Cited 74 times in Scopus74 0
Ariotti, Nicholas, Fernández-Rojo, Manuel, Zhou, Yong, Hill, Michelle M., Rodkey, Travis L., Inder, Kerry L., Tanner, Lukas B., Wenk, Markus R., Hancock, John F. and Parton, Robert G. (2014) Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling. Journal of Cell Biology, 204 5: 777-792. doi:10.1083/jcb.201307055 33   3 Cited 5 times in Scopus5 1
Fernández Rojo, Manuel, Gongora, Milena, Fitzsimmons, Rebecca L., Martel, Nick, Martin, Sheree D., Nixon, Susan, Brooks, Andrew J., Ikonomopoulou, Maria P., Martin, Sally, Lo, Harriet P., Myers, Stephen A., Restall, Christina, Ferguson, Charles, Pilch, Paul F., McGee, Sean L., Anderson, Robin L., Waters, Michael J., Hancock, John F., Grimmond, Sean M., Muscat, George E. and Parton, Robert G. (2013) Caveolin-1 is necessary for hepatic oxidative lipid metabolism: evidence for crosstalk between caveolin-1 and bile acid signaling. Cell Reports, 4 2: 238-247. doi:10.1016/j.celrep.2013.06.017 62   6 Cited 5 times in Scopus5 2
Chadda, Rahul, Howes, Mark T., Plowman, Sarah J., Hancock, John F., Parton, Robert G. and Mayor, Satyajit (2007) Cholesterol-Sensitive Cdc42 Activation Regulates Actin Polymerization for Endocytosis via the GEEC Pathway. Traffic, 8 6: 702-717. doi:10.1111/j.1600-0854.2007.00565.x 86   82 Cited 79 times in Scopus79 0
Howes, Mark T., Kirkham, Matthew, Riches, James, Cortese, Katia, Walser, Piers J., Simpson, Fiona, Hill, Michelle M., Jones, Alun, Lundmark, Richard, Lindsay, Margaret R., Hernandez-Deviez, Delia J., Hadzic, Gordana, McCluskey, Adam, Bashir, Rumasia, Liu, Libin, Pilch, Paul, McMahon, Harvey, Robinson, Phillip J., Hancock, John F., Mayor, Satyajit and Parton, Robert G. (2010) Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells. Journal of Cell Biology, 190 4: 675-691. doi:10.1083/jcb.201002119 113   83 Cited 82 times in Scopus82 1
Walser, Piers, Ariotti, Nicholas, Howes, Mark, Ferguson, Charles, Webb, Richard, Schwudke, Dominik, Leneva, Natalya, Cho, Kwang-Jin, Cooper, Leanne, Rae, James, Floetenmeyer, Matthias, Oorschot, Viola M. J., Skoglund, Ulf, Simons, Kai, Hancock, John F. and Parton, Robert G. (2012) Constitutive formation of caveolae in a bacterium. Cell, 150 4: 752-763. doi:10.1016/j.cell.2012.06.042 78   14 Cited 16 times in Scopus16 15
Hill, Michelle M., Daud, Noor Huda, Aung, Cho Sanda, Loo, Dorothy, Martin, Sally, Murphy, Samantha, Black, Debra M., Barry, Rachael, Simpson, Fiona, Liu, Libin, Pilch, Paul F, Hancock, John F., Marie-Odile Parat and Parton, Robert G. (2012) Co-regulation of cell polarization and migration by caveolar proteins PTRF/cavin-1 and caveolin-1. PLoS One, 7 8: e43041.1-e43041.9. doi:10.1371/journal.pone.0043041 128 1 13 Cited 13 times in Scopus13 1
Ariotti, Nicholas, Liang, Hong, Xu, Yufei, Zhang, Yueqiang, Yonekubo, Yoshiya, Inder, Kerry, Du, Guangwei, Parton, Robert G., Hancock, John F. and Plowman, Sarah J. (2010) Epidermal growth factor receptor activation remodels the plasma membrane lipid environment to induce nanocluster formation. Molecular and Cellular Biology, 30 15: 3795-3804. doi:10.1128/MCB.01615-09 65   29 Cited 30 times in Scopus30 0
Kirkham, Matthew, Nixon, Susan J., Howes, Mark T., Abi-Rached, Laurent, Wakeham, Diane E., Hanzal-Bayer, Michael, Ferguson, Charles, Hill, Michelle M., Fernandez-Rojo, Manuel, Brown, Deborah A., Hancock, John F., Brodsky, Frances M. and Parton, Robert G. (2008) Evolutionary analysis and molecular dissection of caveola biogenesis. Journal of Cell Science, 121 12: 2075-2086. doi:10.1242/jcs.024588 52   41 Cited 44 times in Scopus44 0
van der Hoeven, Dharini, Cho, Kwang-jin, Ma, Xiaoping, Chigurupati, Sravanthi, Parton, Robert G. and Hancock, John F. (2013) Fendiline inhibits K-Ras plasma membrane localization and blocks K-Ras signal transmission. Molecular and Cellular Biology, 33 2: 237-251. doi:10.1128/MCB.00884-12 32   13 Cited 14 times in Scopus14 1
Prior, Ian A., Harding, Angus, Yan, Jun, Sluimer, Judith, Parton, Robert G. and Hancock, John F. (2001) GTP-dependent segregation of H-ras from lipid rafts is required for biological activity. Nature Cell Biology, 3 4: 368-375. doi:10.1038/35070050 69   335 Cited 341 times in Scopus341 0
Payne, Elizabeth, Bowles, Mark R., Don, Alistair, Hancock, John F. and McMillan, Nigel A. J. (2001) Human papillomavirus type 6b virus-like particles are able to activate the Ras-MAP kinase pathway and induce cell proliferation. Journal of Virology, 75 9: 4150-4157. doi:10.1128/JVI.75.9.4150-4157.2001 34   22 Cited 25 times in Scopus25 0
Nicolau, Dan V. (Jnr), Burrage, Kevin, Parton, Robert G. and Hancock, John F. (2006) Identifying optimal lipid raft characteristics required to promote nanoscale protein-protein interactions on the plasma membrane. Molecular and Cellular Biology, 26 1: 313-323. doi:10.1128/MCB.26.1.313-323.2006 62   98 Cited 105 times in Scopus105 1
Hancock, John F. (2006) Lipid rafts: contentious only from simplistic standpoints. Nature Reviews Molecular Cell Biology, 7 6: 456-462. doi:10.1038/nrm1925 68   466 Cited 480 times in Scopus480 0
Tian, Tianhai, Plowman, Sarah J., Parton, Robert G., Kloog, Yoel and Hancock, John F. (2010) Mathematical modeling of K-Ras nanocluster formation on the plasma membrane. Biophysical Journal, 99 2: 534-543. doi:10.1016/j.bpj.2010.04.055 45   16 Cited 16 times in Scopus16 0
Wilkins, Simon J., Yoong, Simon, Verkade, Heather, Mizoguchi, Takamasa, Plowman, Sarah J., Hancock, John F., Kikuchi, Yutaka, Heath, Joan K. and Perkins, Andrew C. (2008) Mtx2 directs zebrafish morphogenetic movements during epiboly by regulating microfilament formation. Developmental Biology, 314 1: 12-22. doi:10.1016/j.ydbio.2007.10.050 63   18 Cited 19 times in Scopus19 0
Inder, Kerry L., Hill, Michelle M. and Hancock, John F. (2010) Nucleophosmin and nucleolin regulate K-Ras signaling. Communicative and Integrative Biology, 3 2: 188-190. doi:10.4161/cib.3.2.10923 39 27 Cited 3 times in Scopus3 0
Hancock, John F. (2007) PA promoted to manager. Nature Cell Biology, 9 6: 615-617. doi:10.1038/ncb0607-615 37   23 Cited 23 times in Scopus23 0
Jaumot, Montserrat and Hancock, John F. (2001) Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions. Oncogene, 20 30: 3949-3958. doi:10.1038/sj.onc.1204526 42   101 Cited 109 times in Scopus109 0
Salim, Angela A., Cho, Kwang-Jin, Tan, Lingxiao, Quezada, Michelle, Lacey, Ernest, Hancock, John F. and Capon, Robert J. (2014) Rare Streptomyces N-formyl amino-salicylamides inhibit oncogenic K-Ras. Organic Letters, 16 19: 5036-5039. doi:10.1021/ol502376e 14   0 Cited 0 times in Scopus0 5
Salim, Angela A., Xiao, Xue, Cho, Kwang-Jin, Piggott, Andrew M., Lacey, Ernest, Hancock, John F. and Capon, Robert J. (2014) Rare Streptomyces sp. polyketides as modulators of K-Ras localisation. Organic and Biomolecular Chemistry, 12 27: 4872-4878. doi:10.1039/c4ob00745j 23   1 Cited 1 times in Scopus1 0
Abankwa, Daniel, Gorfe, Alemayehu A., Inder, Kerry and Hancock, John F. (2010) Ras membrane orientation and nanodomain localization generate isoform diversity. Proceedings of the National Academy of Sciences of the United States of America, 107 3: 1130-1135. doi:10.1073/pnas.0903907107 42   39 Cited 44 times in Scopus44 0
Abankwa, D, Gorfe, A.A and Hancock, John F. (2007) Ras nanoclusters: Molecular structure and assembly. Seminars in Cell and Developmental Bioloby, 18 5: 599-607. doi:10.1016/j.semcdb.2007.08.003 58   45 Cited 48 times in Scopus48 0
Hancock, John F. (2003) Ras proteins: Different signals from different locations. Nature Reviews Molecular Cell Biology, 4 5: 373-384. doi:10.1038/nrm1105 70   426 Cited 434 times in Scopus434 0
Hill, Michelle M., Scherbakov, Nadja, Schiefermeier, Natalia, Baran, JoAnne, Hancock, John F., Huber, Lukas A., Parton, Robert G. and Parat, Marie-Odile (2007) Reassessing the Role of Phosphocaveolin-1 in Cell Adhesion and Migration. Traffic, 8 12: 1695-1705. doi:10.1111/j.1600-0854.2007.00653.x 90   23 Cited 22 times in Scopus22 0
Zhou, Yong, Liang, Hong, Rodkey, Travis, Ariotti, Nicholas, Parton, Robert G. and Hancock, John F. (2013) Signal integration by lipid-mediated spatial cross talk between Ras nanoclusters. Molecular and Cellular Biology, 34 5: 862-876. doi:10.1128/MCB.01227-13 25   2 Cited 3 times in Scopus3 0
Gambin, Yann, Ariotti, Nicholas, McMahon, Kerrie-Ann, Bastiani, Michele, Sierecki, Emma, Kovtun, Oleksiy, Polinkovsky, Mark E., Magenau, Astrid, Jung, WooRam, Okano, Satomi, Zhou, Yong, Leneva, Natalya, Mureev, Sergey, Johnston, Wayne, Gaus, Katharina, Hancock, John F., Collins, Brett M., Alexandrov, Kirill and Parton, Robert G. (2014) Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae. eLIFE, e01434.1-e01434.18. doi:10.7554/eLife.01434 84 2 15
Nicolau Jr, D V, Hancock, John F. and Burrage, Kevin (2007) Sources of Anomalous Diffusion on Cell Membranes: A Monte Carlo Study. Biophysical journal, 92 6: 1975-1987. doi:10.1529/biophysj.105.076869 64   57 Cited 54 times in Scopus54 0
Cho, Kwang-jin, Park, Jin-Hee, Piggott, Andrew M., Salim, Angela A., Gorfe, Alemaheyu A., Parton, Robert G., Capon, Robert J., Lacey, Ernest and Hancock, John F. (2012) Staurosporines disrupt phosphatidylserine trafficking and mislocalize ras proteins. Journal of Biological Chemistry, 287 52: 43573-43584. doi:10.1074/jbc.M112.424457 64   15 Cited 17 times in Scopus17 3
Collins, Brett, Davis, Melissa, Hancock, John F. and Parton, Robert G. (2012) Structure-based reassessment of the caveolin signalling model: Do caveolae regulate signaling through caveolin-protein interactions. Developmental Cell, 23 1: 11-20. doi:10.1016/j.devcel.2012.06.012 49   19 Cited 21 times in Scopus21 0
Sykes, Alex M., Palstra, Nick, Abankwa, Daniel, Hill, Justine M., Skeldal, Sune, Matusica, Dusan, Venkatraman, Prahatha, Hancock, John F. and Coulson, Elizabeth J. (2012) The effects of transmembrane sequence and dimerization on cleavage of the p75 neurotrophin receptor by γ-secretase. Journal of Biological Chemistry, 287 52: 43810-43824. doi:10.1074/jbc.M112.382903 60   7 Cited 7 times in Scopus7 0
Cho, Kwang-jin, Hill, Michelle M., Chigurupati, Sravanthi, Du, Guangwei, Parton, Robert G. and Hancock, John F. (2011) Therapeutic levels of the hydroxmethylglutaryl-coenzyme A reductase inhibitor lovastatin activate Ras signaling via phospholipase D2. Molecular and Cellular Biology, 31 6: 1110-1120. doi:10.1128/MCB.00989-10 67   7 Cited 9 times in Scopus9 0