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Spielmann, Tobias, Hawthorne, Paula L., Dixon, Matthew W. A., Hannemann, Mandy, Klotz, Kathleen, Kemp, David J., Klonis, Nectarios, Tilley, Leann, Trenholme, Katharine R. and Gardiner, Donald L. (2006) A cluster of ring stage-specific genes linked to a locus implicated in cytoadherence in Plasmodium falciparum codes for PEXEL-negative and PEXEL-positive proteins exported into the host cell. Molecular Biology of the Cell, 17 8: 3613-3624. doi:10.1091/mbc.E06-04-0291 63   61 Cited 63 times in Scopus63 1
Peatey, Christopher L., Spicer, Timothy P., Hodder, Peter S., Trenholme, Katharine R. and Gardiner, Donald L. (2011) A high-throughput assay for the identification of drugs against late-stage Plasmodium falciparum gametocytes. Molecular and Biochemical Parasitology, 180 2: 127-131. doi:10.1016/j.molbiopara.2011.09.002 39   23 Cited 23 times in Scopus23 1
Trenholme, Katharine R., Brown, Christopher L., Skinner-Adams, Tina S., Stack, Colin, Lowther, Jonathan, To, Joyce, Robinson, Mark W., Donnelly, Sheila M., Dalton, John P. and Gardiner, Donald L. (2010) Aminopeptidases of malaria parasites: new targets for chemotherapy. Infectious Disorders - Drug Targets, 10 3: 217-225. doi:10.2174/187152610791163363 13   Cited 10 times in Scopus10 0
Hawthorne, Paula L., Trenholme, Katharine R., Skinner-Adams, Tina S., Spielmann, Tobias, Fischer, Katja, Dixon, Matthew W. A., Ortega, Maria R., Anderson, Karen L., Kemp, David J. and Gardiner, Donald L. (2004) A novel Plasmodium falciparum ring stage protein, REX, is located in Maurer's clefts. Molecular and Biochemical Parasitology, 136 2: 181-189. doi:10.1016/j.molbiopara.2004.03.013 117   54 Cited 50 times in Scopus50 0
Trenholme, Katharine R., Boutlis, Craig S., Kuns, Rachel, Lagog, Moses, Bockarie, Moses J., Gatton, Michelle L., Kemp, David J., Good, Michael F., Anstey, Nicholas M. and Gardiner, Donald L. (2005) Antibody reactivity to linear epitopes of Plasmodium falciparum cytoadherence-linked asexual gene 9 in asymptomatic children and adults from Papua New Guinea. American Journal of Tropical Medicine and Hygiene, 72 6: 708-713. 83   8 Cited 9 times in Scopus9
Thivierge, Karine, Mathew, Rency T., Nsangou, Desire M. M., Da Silva, Fabio, Cotton, Sophie, Skinner-Adams, Tina S., Trenholme, Katharine R., Brown, Christopher L., Stack, Colin M., Gardiner, Donald L. and Dalton, John P. (2012) Anti-malaria drug development targeting the M1 alanyl and M17 leucyl aminopeptidases. Arkivoc, 2012 4: 330-346. doi:10.3998/ark.5550190.0013.424 15   1 Cited 1 times in Scopus1 0
Peatey, Christopher L., Andrews, Katherine T., Eickel, Nina, MacDonald, Timothy, Butterworth, Alice S., Trenholme, Katharine R., Gardiner, Donald L., McCarthy, James S. and Skinner-Adams, Tina S. (2010) Antimalarial asexual stage-specific and gametocytocidal activities of HIV protease inhibitors. Antimicrobial Agents and Chemotherapy, 54 3: 1334-1337. doi:10.1128/AAC.01512-09 86   12 Cited 21 times in Scopus21 0
Peatey, Christopher L., Leroy, Didier, Gardiner, Donald L. and Trenholme, Katharine R. (2012) Anti-malarial drugs: How effective are they against Plasmodium falciparum gametocytes?. Malaria Journal, 11 34: 34.1-34.4. doi:10.1186/1475-2875-11-34 56   15 Cited 15 times in Scopus15 5
Skinner-Adams, Tina S., McCarthy, James S., Gardiner, Donald L., Hilton, Petrina M. and Andrews, Katherine T. (2004) Antiretrovirals as antimalarial agents. Journal of Infectious Diseases, 190 11: 1998-2000. doi:10.1086/425584 108   75 Cited 83 times in Scopus83 1
Skinner-Adams, Tina S., Guddat, Luke W., Gardiner, Donald L., McCarthy, James S. and Andrews, Katherine T. (2005) Aspartic proteases of Plasmodium falciparum as the target of HIV-1 protease inhibitors - Reply. Journal of Infectious Diseases, 191 8: 1382-1383. doi:10.1086/428782 103   3 Cited 12 times in Scopus12 0
Stack, Colin M., Lowther, Jonathan, Cunningham, Eithne, Donnelly, Sheila, Gardiner, Donald L., Trenholme, Katharine R., Skinner-Adams, Tina S., Teuscher, Franka, Grembecka, Jolanta, Mucha, Artur, Kafarski, Pawel, Lua, Linda, Bell, Angus and Dalton, John P. (2007) Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase. A protease involved in amino acid regulation with potential for antimalarial drug development. Journal of Biological Chemistry, 282 3: 2069-2080. doi:10.1074/jbc.M609251200 92   51 Cited 48 times in Scopus48 0
Gardiner, Donald L., Spielmann, Tobias, Dixon, Matthew W. A., Hawthorne, Paula L., Ortega, Maria R., Anderson, Karen L., Skinner-Adams, Tina S., Kemp, David J. and Trenholme, Katharine R. (2004) CLAG 9 is located in the rhoptries of Plasmodium falciparum. Parasitology Research, 93 1: 64-67. doi:10.1007/s00436-004-1098-4 86   0 Cited 16 times in Scopus16 0
Holt, Deborah C., Fischer, Katja, Tchavtchitch, Marina, Wilson, Danny W., Hauquitz, Nova E., Hawthorne, Paula L., Gardiner, Donald L., Trenholme, Katharine R. and Kemp, David J. (2001) Clags in Plasmodium falciparum and other species of Plasmodium. Molecular And Biochemical Parasitology, 118 2: 259-263. doi:10.1016/S0166-6851(01)00378-4 53   8 Cited 8 times in Scopus8 0
Skinner-Adams, Tina S., Lawrie, Paula M., Hawthorne, Paula L., Gardiner, Donald L. and Trenholme, Katharine R. (2003) Comparison of Plasmodium falciparum transfection methods. Malaria Journal, 2 19.1-19.4. doi:10.1186/1475-2875-2-19 101   6 Cited 6 times in Scopus6 0
Peatey, Christopher L., Skinner-Adams, Tina S., Dixon, Matthew W. A., McCarthy, James S., Gardiner, Donald L. and Trenholme, Katharine R. (2009) Effect of Antimalarial Drugs on Plasmodium falciparum Gametocytes. The Journal of Infectious Diseases, 200 10: 1518-1521. doi:10.1086/644645 59   31 Cited 35 times in Scopus35 0
Peatey, Christopher L., Watson, Jolanta A., Trenholme, Katharine R., Brown, Christopher L., Nielson, Lars, Guenther, Marko, Timmins, Nicholas, Watson, Gregory S. and Gardiner, Donald L. (2013) Enhanced gametocyte formation in erythrocyte progenitor cells: A site-specific adaptation by Plasmodium falciparum. The Journal of Infectious Diseases, 208 7: 1170-1174. doi:10.1093/infdis/jit309 38   Cited 2 times in Scopus2 1
Chung, Wendy Y., Gardiner, Donald L., Hyland, Catherine, Gatton, Michelle, Kemp, David J. and Trenholme, Katharine R. (2005) Enhanced invasion of blood group A1 erythrocytes by Plasmodium falciparum. Molecular and Biochemical Parasitology, 144 1: 128-130. doi:10.1016/j.molbiopara.2005.08.004 52   11 Cited 11 times in Scopus11 0
Poreba, Marcin, McGowan, Sheena, Skinner-Adams, Tina S., Trenholme, Katharine R., Gardiner, Donald L., Whisstock, James C., To, Joyce, Salvesen, Guy S., Dalton, John P. and Drag, Marcin (2012) Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum. Plos One, 7 2: e31938-1-e31938-8. doi:10.1371/journal.pone.0031938 85   10 Cited 15 times in Scopus15 0
Skinner-Adams, Tina S., Hawthorne, Paula L., Trenholme, Katharine R. and Gardiner, Donald L. (2003) GATEWAY™ vectors for Plasmodium falciparum transfection. Trends in Parasitology, 19 1: 17-18. doi:10.1016/S1471-4922(02)00005-3 77   12 Cited 8 times in Scopus8 0
Skinner-Adams, Tina S., Lowther, Jonathan, Teuscher, Franka, Stack, Colin M., Grembecka, Jolanta, Mucha, Artur, Kafarski, Pawel, Trenholme, Katharine R., Dalton, John P. and Gardiner, Donald L. (2007) Identification of phosphinate dipeptide analog inhibitors directed against the Plasmodium falciparum M17 leucine aminopeptidase as lead antimalarial compounds. Journal of Medicinal Chemistry, 50 24: 6024-6031. doi:10.1021/jm070733v 45   39 Cited 38 times in Scopus38 0
Gardiner, Donald L., Dixon, Matthew W. A., Spielmann, Tobias, Skinner-Adams, Tina S., Hawthorne, Paula L., Ortega, Maria R., Kemp, David J. and Trenholme, Katharine R. (2005) Implication of a Plasmodium falciparum gene in the switch between asexual reproduction and gametocytogenesis. Molecular and Biochemical Parasitology, 140 2: 153-160. doi:10.1016/j.molbiopara.2004.12.010 86   21 Cited 22 times in Scopus22 0
Davies, Mark R., Tran, Thanh N., McMillan, David J., Gardiner, Donald L., Currie, Bart J. and Sriprakash, Kadaba S. (2005) Inter-species genetic movement may blur the epidemiology of streptococcal diseases in endemic regions. Microbes and Infection: A journal on infectious agents and host defenses, 7 9-10: 1128-1138. doi:10.1016/j.micinf.2005.03.018 38   26 Cited 32 times in Scopus32 0
Chung, Wendy Y., Gardiner, Donald L., Hyland, Catharine and Trenholme, Katharine R. (2008) Invasion of Rh null cells by Plasmodium falciparum identifies a new invasion pathway. Parasitology Research, 102 2: 259-263. doi:10.1007/s00436-007-0756-8 56   2 Cited 2 times in Scopus2 0
Gardiner, Donald L., Skinner-Adams, Tina S., Spielmann, Tobias and Trenholme, Katharine R. (2003) Malaria transfection and transfection vectors. Trends In Parasitology, 19 9: 381-383. doi:10.1016/S1471-4922(03)00187-9 66   19 Cited 21 times in Scopus21 0
Raju, Ritesh, Khalil, Zeinab G., Piggott, Andrew M., Blumenthal, Antje, Gardiner, Donald L., Skinner-Adams, Tina S. and Capon, Robert J. (2014) Mollemycin A: an antimalarial and antibacterial glyco-hexadepsipeptide-polyketide from an Australian marine-derived Streptomyces sp. (CMB-M0244). Organic Letters, 16 6: 1716-1719. doi:10.1021/ol5003913 29   1 Cited 1 times in Scopus1 1
Spielmann, Tobias, Gardiner, Donald L., Beck, Hans-Peter, Trenholme, Katharine R and Kemp, David J. (2006) Organization of ETRAMPs and EXP-1 at the parasite-host cell interface of malaria parasites. Molecular Microbiology, 59 3: 779-794. doi:10.1111/j.1365-2958.2005.04983.x 63   33 Cited 37 times in Scopus37 0
Gardiner, Donald L., Trenholme, Katharine R., Skinner-Adams, Tina S., Stack, Colin M. and Dalton, John P. (2006) Overexpression of Leucyl Aminopeptidase in Plasmodium falciparum Parasites. Target for the antimalarial activity of bestatin. Journal of Biological Chemistry, 281 3: 1741-1745. doi:10.1074/jbc.M508955200 53   42 Cited 41 times in Scopus41 1
Andrews, Kathy T., Tran, Thanh N., Lucke, Andrew, Kahnberg, Pia, Lee, G. T., Skinner-Adams, Tina, Gardiner, Donald L. and Fairlie, David P. (2007). Plasmodium falciparum histone deacetylases: Enzymes involved in gene regulation as new antimalarial drug targets. In: Abstract Book: American Society of Tropical Medicine and Hygiene : 56th Annual Meeting. 56th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene, Philadelphia, PA United States, (48-48). 04-08 November 2007. 22   0
Gardiner, Donald L., Skinner-Adams, Tina S., Brown, Christopher L., Andrews, Katherine T., Stack, Colin M., McCarthy, James S., Dalton, John P. and Trenholme, Katharine R. (2009) Plasmodium falciparum: New molecular targets with potential for antimalarial drug development. Expert Review of Anti-Infective Therapy, 7 9: 1087-1098. doi:10.1586/ERI.09.93 55   10 Cited 13 times in Scopus13 0
Vu, Hoan, Roullier, Catherine, Campitelli, Marc, Trenholme, Katharine R., Gardiner, Donald L., Andrews, Katherine T., Skinner-Adams, Tina, Crowther, Gregory J., Van Voorhis, Wesley C. and Quinn, Ronald J. (2013) Plasmodium gametocyte inhibition identified from a natural-product-based fragment library. ACS Chemical Biology, 8 12: 2654-2659. doi:10.1021/cb400582b 26   1 Cited 2 times in Scopus2 11
Andrews, Katherine T., Fairlie, David P., Madala, Praveen K., Ray, John, Wyatt, David M., Hilton, Petrina M., Melville, Lewis A., Beattie, Lynette, Gardiner, Donald L., Reid, Robert C., Stoermer, Martin J., Skinner-Adams, Tina, Berry, Colin and McCarthy, James S. (2006) Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria. Antimicrobial Agents And Chemotherapy, 50 2: 639-648. doi:10.1128/AAC.50.2.639-648.2006 102   77 Cited 82 times in Scopus82 1
Martin, Rowena E., Butterworth, Alice S., Gardiner, Donald L., Kirk, Kiaran, McCarthy, James S. and Skinner-Adams, Tina S. (2012) Saquinavir Inhibits the malaria parasite's chloroquine resistance transporter. Antimicrobial Agents and Chemotherapy, 56 5: 2283-2289. doi:10.1128/AAC.00166-12 43   11 Cited 12 times in Scopus12 0
McGowan, Sheena, Porter, Corrine J., Lowther, Jonathan, Stack, Colin M., Golding, Sarah J., Skinner-Adams, Tina S., Trenholme, Katharine R., Teuscher, Franka, Donnelly, Sheila M., Grembecka, Jolanta, Mucha, Artur, Kafarski, Pawel, DeGori, Ross, Buckle, Ashley M., Gardiner, Donald L., Whisstock, James C. and Dalton, John P. (2009) Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase. Proceedings of the National Academy of Sciences of USA, 106 8: 2537-2542. doi:10.1073/pnas.0807398106 33   57 Cited 59 times in Scopus59 7
Hanssen, Eric, Hawthorne, Paula, Dixon, Matthew W. A., Trenholme, Katharine R, McMillan, Paul J., Spielmann, Tobias, Gardiner, Donald L. and Tilley, Leann (2008) Targeted mutagenesis of the ring-exported protein-1 of Plasmodium falciparum disrupts the architecture of Maurer's cleft organelles. Molecular Microbiology, 69 4: 938-953. doi:10.1111/j.1365-2958.2008.06329.x 77   32 Cited 33 times in Scopus33 0
Dixon, Matthew W. A., Hawthorne, Paula L., Spielmann, Tobias, Anderson, Karen L., Trenholme, Katharine R. and Gardiner, Donald L. (2008) Targeting of the ring exported protein 1 to the Maurer's Clefts is mediated by a two-phase process. Traffic, 9 8: 1316-1326. doi:10.1111/j.1600-0854.2008.00768.x 74   32 Cited 37 times in Scopus37 0
Peatey, Christopher L., Dixon, Matthew W. A., Gardiner, Donald L. and Trenholme, Katharine R. (2013) Temporal evaluation of commitment to sexual development in Plasmodium falciparum. Malaria Journal, 12 . doi:10.1186/1475-2875-12-134 29   2 Cited 2 times in Scopus2 1
Sivaraman, Komagal Kannan, Oellig, Christine A., Huynh, Kitmun, Atkinson, Sarah C., Poreba, Marcin, Perugini, Matthew A., Trenholme, Katharine R., Gardiner, Donald L., Salvesen, Guy, Drag, Marcin, Dalton, John P., Whisstock, James C. and McGowan, Sheena (2012) X-ray crystal structure and specificity of the plasmodium falciparum malaria aminopeptidase PfM18AAP. Journal of Molecular Biology, 422 4: 495-507. doi:10.1016/j.jmb.2012.06.006 46   8 Cited 6 times in Scopus6 1