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Fairlie, DP, Wickramasinghe, WA, Byriel, KA and Taube, H (1997) Activation of thiourea bound through sulfur to pentaammineruthenium(III): Structure and reactivity. Inorganic Chemistry, 36 11: 2242-2243. doi:10.1021/ic9611397 71   11 Cited 13 times in Scopus13 0
Barry, GD, Le, GT and Fairlie, DP (2006) Agonists and antagonists of protease activated receptors (PARs). Current Medicinal Chemistry, 13 3: 243-265. doi:10.2174/092986706775476070 222   45 Cited 46 times in Scopus46 0
Fairlie, DP, Woo, TC, Wickramasinghe, WA and Willis, AC (1994) Amide-Iminol Tautomerism - Effect of Metalation. Inorganic Chemistry, 33 26: 6425-6428. doi:10.1021/ic00104a067 126   40 0
Glenn, MP, Kahnberg, P, Boyle, GM, Hansford, KA, Hans, D, Martyn, AC, Parsons, PG and Fairlie, DP (2004) Antiproliferative and phenotype-transforming antitumor agents derived from cysteine. Journal of Medicinal Chemistry, 47 12: 2984-2994. doi:10.1021/jm030222i 64   23 Cited 25 times in Scopus25 0
Loughlin, WA, Tyndall, JDA, Glenn, MP and Fairlie, DP (2004) Beta-strand mimetics. Chemical Reviews, 104 12: 6085-6117. doi:10.1021/cr040648k 61   140 Cited 140 times in Scopus140 0
Glenn, MP, Pattenden, LK, Reid, RC, Tyssen, DP, Tyndall, JDA, Birch, CJ and Fairlie, DP (2002) beta-strand mimicking macrocyclic amino acids: Templates for protease inhibitors with antiviral activity. Journal of Medicinal Chemistry, 45 2: 371-381. doi:10.1021/jm010414i 117   44 Cited 45 times in Scopus45 0
Reid, RC, Kelso, MJ, Scanlon, MJ and Fairlie, DP (2002) Conformationally constrained macrocycles that mimic tripeptide beta-strands in water and aprotic solvents. Journal of The American Chemical Society, 124 20: 5673-5683. doi:10.1021/ja0256461 119   38 Cited 36 times in Scopus36 0
Wong, AK, Finch, AM, Pierens, GK, Taylor, SM and Fairlie, DP (1997) Conformationally constrained small molecule antagonists of C5a.. Abstracts of Papers of The American Chemical Society, 214 9-MEDI. 51   0
Glenn, MP, Kelso, MJ, Tyndall, JDA and Fairlie, DP (2003) Conformationally homogeneous cyclic tetrapeptides: Useful new three-dimensional scaffolds. Journal of The American Chemical Society, 125 3: 640-641. doi:10.1021/ja029205t 50   33 Cited 35 times in Scopus35 0
Huang, XD, Cuajungco, MP, Atwood, CS, Hartshorn, MA, Tyndall, JDA, Hanson, GR, Stokes, KC, Leopold, M, Multhaup, G, Goldstein, LE, Scarpa, RC, Saunders, AJ, Lim, J, Moir, RD, Glabe, C, Bowden, EF, Masters, CL, Fairlie, DP, Tanzi, RE and Bush, AI (1999) Cu(II) potentiation of Alzheimer A beta neurotoxicity - Correlation with cell-free hydrogen peroxide production and metal reduction. Journal of Biological Chemistry, 274 52: 37111-37116. doi:10.1074/jbc.274.52.37111 43   535 Cited 561 times in Scopus561 0
Fairlie, DP, Dutton, BH, Mckeon, JA and Jackson, WG (2002) Deactivation of the chlorosulfonate ion coordinated to pentaamminecobalt(III). Inorganic Reaction Mechanisms, 4 3-4: 197-208. doi:10.1080/1028662021000062626 89   0 0
Lucke, AJ, Tyndall, JDA, Singh, Y and Fairlie, DP (2003) Designing supramolecular structures from models of cyclic peptide scaffolds with heterocyclic constraints. Journal of Molecular Graphics & Modelling, 21 5: 341-355. doi:10.1016/S1093-3263(02)00181-X 79   29 Cited 29 times in Scopus29 0
Haynes, DR, Harkin, DG, Bignold, LP, Hutchens, MJ, Taylor, SM and Fairlie, DP (2000) Inhibition of C5a-induced neutrophil chemotaxis and macrophage cytokine production In Vitro by a new C5a receptor antagonist. Biochemical Pharmacology, 60 5: 729-733. doi:10.1016/S0006-2952(00)00361-0 100   41 Cited 41 times in Scopus41 0
Tyndall, JDA and Fairlie, DP (2001) Macrocycles mimic the extended peptide conformation recognized by aspartic, serine, cysteine and metallo proteases. Current Medicinal Chemistry, 8 8: 893-907. 95   67
Fairlie, DP, Le, GT, Halili, M, Ruiz-Gomez, G and Abbenante, J (2008). MEDI 256-Activation and inhibition of latent serine proteases, complement factors B and C2. In: Abstracts of papers of the American Chemical Society. 236th National Meeting of the American Chemical Society, Philadelphia PA, (). 17-21 August 2008. 40   0
Scanlon, MJ, Fairlie, DP, Craik, DJ, Englebretsen, DR and West, ML (1995) Nmr Solution Structure of the Rna-Binding Peptide From Human-Immunodeficiency-Virus (type-1) Rev. Biochemistry, 34 26: 8242-8249. doi:10.1021/bi00026a005 25   24 0
Blakeney, JS and Fairlie, DP (2005) Nonpeptide ligands that target peptide-activated GPCRs in inflammation. Current Medicinal Chemistry, 12 25: 3027-3042. doi:10.2174/092986705774462888 121   13 Cited 15 times in Scopus15 0
Paczkowski, NJ, Finch, AM, Whitmore, JB, Short, AJ, Wong, AK, Monk, PN, Cain, SA, Fairlie, DP and Taylor, SM (1999) Pharmacological characterization of antagonists of the C5a receptor. British Journal of Pharmacology, 128 10: 1461-1466. doi:10.1038/sj.bjp.0702938 51   65 0
Suen, JY, Gardiner, B, Grimmond, S and Fairlie, DP (2010) Profiling gene expression induced by protease-activated receptor 2 (PAR2) activation in human kidney cells. PLoS One, 5 11: e13809-1-e13809-14. doi:10.1371/journal.pone.0013809 39   22 Cited 23 times in Scopus23 0
Abey, HT, Fairlie, DP, Moffatt, JD, Balzary, RW and Cocks, TM (2006) Protease-activated receptor-2 peptides activate neurokinin-1 receptors in the mouse isolated trachea. Journal of Pharmacology And Experimental Therapeutics, 317 2: 598-605. doi:10.1124/jpet.105.097121 71   18 Cited 19 times in Scopus19 0
Tyndall, JDA, Nall, T and Fairlie, DP (2005) Proteases universally recognize beta strands in their active sites. Chemical Reviews, 105 3: 973-999. doi:10.1021/cr040669e 77   206 Cited 214 times in Scopus214 3
Abbenante, G, March, DR, Bergman, DA, Hunt, PA, Garnham, B, Dancer, RJ, Martin, JL and Fairlie, DP (1995) Regioselective Structural and Functional Mimicry of Peptides - Design of Hydrolytically-Stable Cyclic Peptidomimetic Inhibitors of Hiv-1 Protease. Journal of the American Chemical Society, 117 41: 10220-10226. doi:10.1021/ja00146a007 22   50 Cited 48 times in Scopus48 0
Singh, Y, Stoermer, MJ, Lucke, AJ, Glenn, MP and Fairlie, DP (2002) Regioselective synthesis of antiparallel loops on a macrocyclic scaffold constrained by oxazoles and thiazoles. Organic Letters, 4 20: 3367-3370. doi:10.1021/ol026463m 44   26 Cited 24 times in Scopus24 0
Taylor, SM and Fairlie, DP (2000) Regulators of the anaphylatoxin C5a. Expert Opinion in Therapeutic Patents, 10 4: 449-458. doi:10.1517/13543776.10.4.449 38   13 0
Singh, Y, Hoang, HN, Flanagan, B and Fairlie, DP (2006) Self-condensation of a thiazole-peptide bearing a 21-membered loop into a library of giant macrocycles with multiple orthogonal loops. Organic Letters, 8 6: 1053-1056. doi:10.1021/ol052842e 62   1 Cited 1 times in Scopus1 0
Wong, AK, Finch, AM, Pierens, GK, Craik, DJ, Taylor, SM and Fairlie, DP (1998) Small molecular probes for G-protein-coupled C5a receptors: Conformationally constrained antagonists derived from the C terminus of the human plasma protein C5a. Journal of Medicinal Chemistry, 41 18: 3417-3425. doi:10.1021/jm9800651 59   62 Cited 59 times in Scopus59 0
Fairlie, DP (2004) Small molecules that mimic components of bioactive protein surfaces. Australian Journal of Chemistry, 57 9: 855-857. doi:10.1071/CH04074 87   6 Cited 5 times in Scopus5 0
Coles, M, Bicknell, W, Watson, AA, Fairlie, DP and Craik, DJ (1998) Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?. Biochemistry, 37 31: 11064-11077. doi:10.1021/bi972979f 267   319 Cited 315 times in Scopus315 0
Watson, AA, Fairlie, DP and Craik, DJ (1998) Solution structure of methionine-oxidized amyloid beta-peptide (1-40). Does oxidation affect conformational switching?. Biochemistry, 37 37: 12700-12706. doi:10.1021/bi9810757 186   102 Cited 103 times in Scopus103 0
Singh, Y, Stoermer, MJ, Lucke, AJ, Guthrie, T and Fairlie, DP (2005) Structural mimicry of two cytochrome b(562) interhelical loops using macrocycles constrained by oxazoles and thiazoles. Journal of The American Chemical Society, 127 18: 6563-6572. doi:10.1021/ja0455300 70   28 Cited 29 times in Scopus29 0
Comba, P, Cusack, R, Fairlie, DP, Gahan, LR, Hanson, GR, Kazmaier, U and Ramlow, A (1998) The solution structure of a copper(II) compound of a new cyclic octapeptide by EPR spectroscopy and force field calculations. Inorganic Chemistry, 37 26: 6721-6727. doi:10.1021/ic9809299 92   31 0
Warrener, R, Beamish, H, Burgess, A, Waterhouse, NJ, Giles, N, Fairlie, DP and Gabrielli, B (2003) Tumor cell-specific cytotoxicity by targeting cell cycle checkpoints. Faseb Journal, 17 9: 1550-1570. doi:10.1096/fj.02-1003fje 139   104 Cited 109 times in Scopus109 0