Centre for Integrated Preclinical Drug Development Publications

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Mercer, Luke, Bowling, Tana, Perales, Joe, Freeman, Jennifer, Nguyen, Tien, Bacchi, Cyrus, Yarlett, Nigel, Don, Robert, Jacobs, Robert and Nare, Bakela (2011) 2,4-diaminopyrimidines as potent inhibitors of trypanosoma brucei and identification of molecular targets by a chemical proteomics approach. PLoS Neglected Tropical Diseases, 5 2: e956-1-e956-10. doi:10.1371/journal.pntd.0000956 84   19 Cited 23 times in Scopus23 0
Edwards, Stephen R., Coulson, Elizabeth J. and Smith, Maree T. (2010). A behavioural study assessing memory deficits in the APP/PS1 double transgenic mouse model of Alzheimer’s disease using the Morris water maze.. In: Found in translation: Integrated approaches to drug development. Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) 44th Annual Scientific Meeting 2010, Melbourne, Australia, (10-10). 28 November-1 December 2010. 169  
Chik, Zamri, Basu, Roma Choudhury, Pendek, Rokiah, Lee, Toong Chow and Mohamed, Zahurin (2010) A Bioequivalence Comparison of Two Formulations of Rifampicin (300 mg vs 150 mg Capsules): An Open-Label, Randomised, Two-Treatment, Two-Way Crossover Study in Healthy Volunteers. Clinical Therapeutics, 32 10: 1822-1831. doi:10.1016/j.clinthera.2010.09.006 136   3 Cited 4 times in Scopus4 0
Wiliem, Arnold, Madasu, Vamsi, Boles, Wageeh and Yarlagadda, Prasad (2009). A context-based approach for detecting suspicious behaviours. In: Proceedings 2009 Digital Image Computing:Techniques and Applications DICTA 2009. DICTA 2009: Digital Image Computing:Techniques and Applications, Melbourne, VIC, Australia, (146-153). 1-3 December 2009. doi:10.1109/DICTA.2009.31 101   4 Cited 4 times in Scopus4 0
Wiliem, A., Madasu, V., Boles, W. and Yarlagadda, P. (2009). Adaptive unsupervised learning of human actions. In: Proceedings of 3rd International Conference on Crime Detection and Prevention (ICDP 2009). 3rd International Conference on Imaging for Crime Detection and Prevention (ICDP 2009), London United Kingdom, (). 3 December 2009. doi:10.1049/ic.2009.0257 44   0 0
Ghassabian, Sussan, Chetty, Manoranjenni, Tattam, Bruce N., Glen, John, Rahme, Jeannie, Stankovic, Zvijezdana, Ramzan, Iqbal, Murray, Michael and McLachlan, Andrew J. (2009) A high-throughput assay using liquid chromatography-tandem mass spectrometry for simultaneous in vivo phenotyping of 5 major cytochrome p450 enzymes in patients. Therapeutic Drug Monitoring, 31 2: 239-246. doi:10.1097/FTD.0b013e318197e1bf 69   14 Cited 16 times in Scopus16 2
Shekar, K., Diab, S., McDonald, C., Fisquet, S., Dunster, K., Fung, L., Platts, D., Ghassabian, S., Barnett, A., Roberts, J., Smith, M. and Fraser, J. (2012). Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation may cause therapeutic failure. In: Abstracts for the Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting. Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting, Brisbane, QLD, Australia, (S235-S236). 16-19 August 2012. doi:10.1016/j.hlc.2012.05.581     0
Ziora, Zyta and Kafarski, Pawel (2009) Amidoalkylation of Phosphorus Trichloride with Acetamide and Alkyl Oxocycloalkanecarboxylates. Phosphorus, Sulfur, and Silicon and the Related Elements, 184 4: 1047-1053. doi:10.1080/10426500902737356 160   3 Cited 3 times in Scopus3 0
Muralidharan, Arjun, Wyse, Bruce D. and Smith, Maree T. (2014) Analgesic efficacy and mode of action of a selective small molecule angiotensin II type 2 receptor antagonist in a rat model of prostate cancer-induced bone pain. Pain Medicine, 15 1: 93-110. doi:10.1111/pme.12258 181   8 Cited 10 times in Scopus10 0
Smith, Maree, Muralidharan, Arjun and Praveen, Anand (2014). Analgesic efficacy and mode of action of small molecule Angiotensin II type 2 receptor (AT2R) antagonists for neuropathic and inflammatory pain. In: 34 th Annual Scientific Meeting of the Australian Pain Society, Hobart , Australia, (). 13 - 16 April 2014. 20  
Smith, Maree T., Lau, Tanya, Wallace, Victoria C. J., Wyse, Bruce D. and Rice, Andrew S. C. (2014) Analgesic efficacy of small-molecule angiotensin II type 2 receptor antagonists in a rat model of antiretroviral toxic polyneuropathy. Behavioural Pharmacology, 25 2: 137-146. doi:10.1097/FBP.0000000000000025 54   7 Cited 9 times in Scopus9 1
South, S. M. and Smith, M. T. (2001) Analgesic tolerance to opioids. Pain: Clinical Updates, 9 5: 1-4. 159  
Chik, Z., Mustafa, A. M., Mohamed, Z. and Lee, T. C. (2010) Analysis of Captopril in Human Plasma Using Gas Chromatography-Mass Spectrometry (GCMS) with Solid-Phase Extraction (SPE). Current Analytical Chemistry, 6 4: 329-333. 100   0 0
Madasu, Vamsi Krishna and Lovell, Brian C. (2008). An Automatic Offline Signature and Forgery Detection System. In Brijesh Verma and Michael Blumenstein (Ed.), Pattern recognition technologies and applications : Recent advances (pp. 63-89) Hersey, PA: Information Science Reference. 479  
Ghassabian, Sussan, Griffiths, Lyn and Smith, Maree T (2015) A novel fully validated LC-MS/MS method for quantification of pyridoxal-5'-phosphate concentrations in samples of human whole blood. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1000 77-83. doi:10.1016/j.jchromb.2015.07.019 11 1 0 Cited 2 times in Scopus2 0
Jia, Husen, Dwyer, Simon A., Fan, Da-Yong, Han, Yaqin, Badger, Murray R., von Caemmerer, Susanne and Chow, Wah Soon (2014) A novel P700 redox kinetics probe for rapid, non-intrusive and whole-tissue determination of photosystem II functionality, and the stoichiometry of the two photosystems in vivo. Physiologia Plantarum, 152 3: 403-413. doi:10.1111/ppl.12235 31   Cited 1 times in Scopus1 0
Khan, Nemat, Gordon, Richard, Woodruff, Trent M. and Smith, Maree T. (2015) Antiallodynic effects of alpha lipoic acid in an optimized RR-EAE mouse model of MS-neuropathic pain are accompanied by attenuation of upregulated BDNF-TrkB-ERK signalling in the dorsal horn of the spinal cord. Pharmacology Research and Perspectives, 3 3: 1-16. doi:10.1002/prp2.137 44   1
Smith, M. T., Nielsen, C., Lewis, R., Alewood, D. and Drinkwater, R. D. (2004). Anti-allodynic effects of Xen2174 in rats with neuropathy. Abstract. In: Proceedings of ANZCA Annual Scientific Meeting. ANZCA Annual Scientific Meeting, Perth, Western Australia, (141). 1-5 May, 2004. 114  
Nielsen, C., Smith, M. T., Lewis, R., Alewood, D. and Drinkwater, R. D. (2004). Anti-allodynic efficacy of the chi-conopeptide, Xen2174, in rats with neuropathic pain. In: Warwick P. Anderson, Clinical and Experimental Pharmacology and Physiology: Abstracts of the 8th World Congress on Clinical Pharmacology & Therapeutics. CPT2004: 8th World Congress on Clinical Pharmacology & Therapeutics, Brisbane, Qld, Australia, (A119-A119). 1-6 August, 2004. doi:10.1111/j.1440-1681.2004.cep_4027.pdf.x 167   0
Edwards, S. R., Mather, L. E. and Smith, M. T. (2005). Antihyperalgesic and anti-inflammatory effects of RS- & S-ketamine in freunds complete adjuvant (FCA)-induced inflammation. In: Abstracts, 11th World Congress on Pain. 11th World Congress on Pain, Sydney, (1542-P45). 21-26 August 2005. 1134  
South, SM and Smith, MT (1998) Apparent insensitivity of the hotplate latency test for detection of antinociception following intraperitoneal, intravenous or intracerebroventricular M6G administration to rats. Journal of Pharmacology And Experimental Therapeutics, 286 3: 1326-1332. 152   23
Zin, Che S., Nissen, Lisa M., O'Callaghan, James P., Duffull, Stephen B., Smith, Maree T. and Moore, Brendan J. (2010) A randomized, controlled trial of oxycodone versus placebo in patients with postherpetic neuralgia and painful diabetic neuropathy treated with pregabalin. Journal of Pain, 11 5: 462-471. doi:10.1016/j.jpain.2009.09.003 89   44 Cited 50 times in Scopus50 0
Smith, Maree T., Woodruff, Trent M., Wyse, Bruce D., Muralidharan, Arjun and Walther, Thomas (2013) A small molecule angiotensin II type 2 receptor (AT2R) antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 Mitogen-Activated Protein Kinase (MAPK) and p44/p42 MAPK activation in the dorsal root ganglia. Pain Medicine, 14 10: 1557-1568. doi:10.1111/pme.12157 86   16 Cited 22 times in Scopus22 4
Edwards, Stephen and Smith, M.T. (2009). A study of the application of the Morris water maze to the establishment of a preclinical model of Alzheimer's disease in the rat. In: ASCEPT 43rd Annual Scientific Meeting 2009: The Rights of Medicines, Darling Harbour, NSW, Australia, (). 29 November-2 December 2009. 69  
Smith, GD, Prankerd, RJ and Smith, MT (1997) Biochemical synthesis, purification and preliminary pharmacological evaluation of normorphine-3-glucuronide. Life Sciences, 61 2: 95-104. doi:10.1016/S0024-3205(97)00364-0 164   5 Cited 4 times in Scopus4 0
Kumar, A., Hanmandlu, M., Madasu, V. K. and Lovell, B. C. (2009). Biometric Authentication Based on Infrared Thermal Hand Vein Patterns. In: Digital Image Computing: Techniques and Applications, 2009. DICTA '09. Digital Image Computing: Techniques and Applications, 2009. DICTA '09, Melbourne, Victoria, Australia, (331-338). 1-3 December, 2009. doi:10.1109/DICTA.2009.63 88 4 3 Cited 13 times in Scopus13 0
Madasu, Vamsi K. and Lovell, Brian C. (2009). Blotch detection in pigmented skin lesions using fuzzy co-clustering and texture segmentation. In: Hao Shi, Yanchun Zhang, Murk J. Bottema, Brian C. Lovell and Anthony J. Maeder, 2009 Digital Image Computing: Techniques and Applications. DICTA 2009, Melbourne , Australia, (25-31). 1-3 December 2009. doi:10.1109/DICTA.2009.15 124 1 6 Cited 6 times in Scopus6 0
Halliday, Andrew J., Bartlett, Selena E., Colditz, Paul and Smith, Maree T. (1999) Brain region-specific studies of the excitatory behavioral effects of morphine-3-glucuronide. Life Sciences, 65 2: 225-236. doi:10.1016/S0024-3205(99)00239-8 289   23 0
Smith, M. T., Wright, A. W., Williams, B., Stuart, G. and Cramond, T. R. (1999) Cerebrospinal fluid and plasma concentrations of morphine, morphine-3-glucuronide, and morphine-6-glucuronide in patients before and after initiation of intracerebroventricular morphine for cancer pain management. Anesthesia and analgesia, 88 1: 109-116. doi:10.1097/00000539-199901000-00021 128   23 Cited 28 times in Scopus28 0
Cheung, Chi Wai, Qiu, Qiu, Choi, Siu-Wai, Moore, Brendan, Goucke, Roger and Irwin, Michael (2014) Chronic opioid therapy for chronic non-cancer pain: a review and comparison of treatment guidelines. Pain Physician, 17 5: 401-414. 44 116 8 0
Hanmandlu, Madasu, Madasu, Vamsi Krishna and Vasikarla, Shantaram (2003). Cluster Weighted Modeling as a Basis for Fuzzy Modeling. In: P. Srimani, Proceedings of the International Conference on Information Technology: Computers and Communications. International Conference on Information Technology - Coding and Computing, Las Vegas, USA, (627-634). 28-30 April, 2003. 180 177 2
Smith, MT and de la Iglesia, FA (2005) Co-administration of oxycodone and morphine and analgesic synergy re-examined. British Journal of Clinical Pharmacology, 59 4: 486-487. doi:10.1111/j.1365-2125.2005.02345_1.x 75   2 Cited 3 times in Scopus3 0
Smith, M. T. (2006). Combining opioids - Preclinical and clinical studies. In: Proceedings of the 7th Biennial Conference of the Australian and New Zealand Society of Palliative Medicine. 7th Biennial Conference of the Australian and New Zealand Society of Palliative Medicine, Newcastle, (31). 4-6 October 2006. 77  
Smith, Maree T. and Muralidharan, Arjun (2013) Comment On "protective Arms of the Renin-Angiotensin System in Neurological Disease". Clinical and Experimental Pharmacology and Physiology, 40 11: 838-838. doi:10.1111/1440-1681.12169 42   0 0 0
Chik, Z, Basu, R. C, Pendek, R, Lee, T. C. and Mohamed, Z. (2009) Comparative bioavailability study of two salbutamol tablets in healthy adult volunteers. International Journal of Clinical Pharmacology and Therapeutics, 47 6: 413-418. 65   1 0
Huang, L., Edwards, S. R. and Smith, M. T. (2004). Comparative pharmacokinetics and metabolism of subcutaneous oxycodone in male dark agouti relative to sprague-dawley rats. In: Warwick P. Anderson, 8th World Congress on Clinical Pharmacology & Therapeutics - Abstracts. CTP 2004, Brisbane, (254-254). 1-6 August 2004. 135  
Hemstapat, K., Le, L., Edwards, S. R. and Smith, M. T. (2009) Comparative studies of the neuro-excitatory behavioural effects of morphine-3-glucuronide and dynorphin A (2-17) following spinal and supraspinal routes of administration. Pharmacology, Biochemistry and Behaviour, 93 4: 498-505. doi:10.1016/j.pbb.2009.06.016 107   4 Cited 6 times in Scopus6 3
Muralidharan, Arjun, Kuo, Andy, Jacob, Meera, Lourdesamy, Jacintha S., Melo Sores Pinho De Carvalho, Lara, Nicholson, Janet R., Corradini, Laura and Smith, Maree T. (2016) Comparison of burrowing and stimuli-evoked pain behaviors as end-points in rat models of inflammatory pain and peripheral neuropathic pain. Frontiers in Behavioral Neuroscience, 10 88: . doi:10.3389/fnbeh.2016.00088     0 0 1
Huang, L., Edwards, S. R. and Smith, M. T. (2005) Comparison of the pharmacokinetics of oxycodone and noroxycodone in male dark agouti and Sprague-Dawley rats: Influence of streptozotocin-induced diabetes. Pharmaceutical Research, 22 9: 1489-1498. doi:10.1007/s11095-005-6154-y 289   13 Cited 11 times in Scopus11 1
Abdelrahim, Adel. S., Ziora, Zyta M., Bergeon, Julie A., Moss, Anne R. and Toth, Istvan (2009) Design and synthesis of a series of novel, cationic liposaccharide derivatives as potential penetration enhancers for oral drug delivery. Tetrahedron, 65 45: 9436-9442. doi:10.1016/j.tet.2009.08.072 86   6 Cited 8 times in Scopus8 0
Susan, Seba, Hanmandlu, M., Madasu, Vamsi K. and Lovell, Brian C. (2009). Detection of skin lesions by fuzzy entropy based texel identification. In: Peter Zinterhof, Sven Loncaric, Andreas Uhl and Alberto Carini, Proceedings of the 6th International Symposium on Image and Signal Processing and Analysis. ISPA 2009, Salzburg, Austria, (244-249). 16-18 September 2009. 114  
Edwards, S. R. and Smith, M. T. (2004). Determination of morphine, oxycodone, morphine-3-glucuronide, & noroxycodone concentrations in rat serum by liquid chromatography (LC) - electrospray mass spectrometry (EMS). In: Warwick P. Anderson, 8th World Conference on Clinical Pharmacology & Therapeutics 2004 - Abstracts. CPT2004, Brisbane, (152-152). 1-6 August 2004. 207  
Ghassabian, Sussan, Rethwan, Ahmad, Griffiths, Lyn and Smith, Maree (2014). Development and validation of an lc-ms/ms bioanalytical method for quantification of homocysteine (hcy) in samples of human serum. In: International Pharmaceutical Federation (FIP), Melbourme, Australia, (). 13-16 April 2014.    
Ghassabian, Sussan, Wright, Linda A., deJager, Andrew D. and Smith, Maree T. (2012) Development and validation of a sensitive solid-phase-extraction (SPE) method using high-performance liquid chromatography/tandem mass spectrometry (LC-MS/MS) for determination of risedronate concentrations in human plasma. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 881-82 34-41. doi:10.1016/j.jchromb.2011.11.031 94   7 Cited 7 times in Scopus7 0
Vitetta, Luis, Coulson, Samantha, Schloss, Janet, Beck, Shoshannah L., Allen, Robert and Sali, Avni (2012) Dietary recommendations for patients with rheumatoid arthritis: A review. Nutrition and Dietary Supplements, 4 1-15. doi:10.2147/NDS.S6922 166 14 3
Patterson, M., Ross, F. B. and Smith, M. T. (2001). Differential changes in the potency of supraspinally administered oxycodone relative to morphine for the alleviation of tactile allodynia in adult male Dark Agouti rats with streptozotocin-induced diabetes. In: W.C. Hodgson and R.E. Loiacono, Abstracts of the Annual Scientific Meeting of ASCEPT. ASCEPT Annual Scientific Meeting, Dunedin, New Zealand, (80-80). 3 - 5 December, 2001. 64  
He, H., Friese, M. E. J., Heckenberg, N. R. and Rubinsztein-Dunlop, H. (2003). Direct Observation of Transfer of Angular Momentum to Absorptive Particles from a Laser Beam with a Phase Singularity. In l. Allen, S. M. Barnett and M. J. Padgett (Ed.), Optical Angular Momentum (pp. 199-202) Boca Raton, FL, U.S.A.: CRC Press. 103  
Nare, Bakela, Wring, Stephen, Bacchi, Cyrus, Beaudet, Beth, Bowling, Tana, Brun, Reto, Chen, Daitao, Ding, Charles, Freund, Yvonne, Gaukel, Eric, Hussain, Ali, Jarnagin, Kurt, Jenks, Matthew, Kaiser, Marcel, Mercer, Luke, Mejia, Elena, Noe, Andy, Orr, Matt, Parham, Robin, Plattner, Jacob, Randolph, Ryan, Rattendi, Donna, Rewerts, Cindy, Sligar, Jacob, Yarlett, Nigel, Don, Robert and Jacobs, Robert (2010) Discovery of novel orally bioavailable oxaborole 6-carboxamides that demonstrate cure in a murine model of late-stage central nervous system African trypanosomiasis. Antimicrobial Agents and Chemotherapy, 54 10: 4379-4388. doi:10.1128/AAC.00498-10 67   35 Cited 36 times in Scopus36 0
Wells, J. A., Punjanon, T. and Smith, M. T. (2002). Electrolyte removal from artificial CSF by HPLC to restore ESI-MS/MS signal intensity in quantification of morphine and its glucuronide metabolites. In: Abstracts 10th World Congress on Pain. 10th World Congress on Pain, San Diego, (59-59). 17-22 Aug. 2002. 131  
Wells, J. A., Punjanon, T., Wright, A. W. and Smith, M. T. (2001). Electrolyte removal is essential for optimizing ESI-MS/MS signal intensity for the quantification of morphine and morphine-3-glucuronide in samples of rat brain microdialysate. In: W. C. Hodgson and R. E. Loiacono, Abstracts of the Annual Scientific Meeting of ASCEPT. Annual Scientific Meeting of ASCEPT 2001, Dunedin, New Zealand, (84-84). 3 - 5 December, 2001. 138  

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