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List of Records in Centre for Integrated Preclinical Drug Development Publications

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  Abstract Views File Downloads ResearcherID Citation Count
South, S. M. and Smith, M. T. (2001) Analgesic tolerance to opioids. Pain: Clinical Updates, 9 5: 1-4. 50    
Smith, M. T., Nielsen, C., Lewis, R., Alewood, D. and Drinkwater, R. D. (2004). Anti-allodynic effects of Xen2174 in rats with neuropathy. Abstract. In: , Proceedings of ANZCA Annual Scientific Meeting. ANZCA Annual Scientific Meeting, Perth, Western Australia, (141). 1-5 May, 2004. 21    
Nielsen, C., Smith, M. T., Lewis, R., Alewood, D. and Drinkwater, R. D. (2004). Anti-allodynic efficacy of the chi-conopeptide, Xen2174, in rats with neuropathic pain. In: Warwick P. Anderson, 8th World Conference on Clinical Pharmacology & Therapeutics 2004 - Abstracts. CPT2004, Brisbane, (252). 1-6 August 2004. 15    
Edwards, S. R., Mather, L. E. and Smith, M. T. (2005). Antihyperalgesic and anti-inflammatory effects of RS- & S-ketamine in freunds complete adjuvant (FCA)-induced inflammation. In: , Abstracts, 11th World Congress on Pain. 11th World Congress on Pain, Sydney, (1542-P45). 21-26 August 2005. 492    
South, SM and Smith, MT (1998) Apparent insensitivity of the hotplate latency test for detection of antinociception following intraperitoneal, intravenous or intracerebroventricular M6G administration to rats. Journal of Pharmacology And Experimental Therapeutics, 286 3: 1326-1332. 80   14
Smith, GD, Prankerd, RJ and Smith, MT (1997) Biochemical synthesis, purification and preliminary pharmacological evaluation of normorphine-3-glucuronide. Life Sciences, 61 : 95-104. 53   5
Halliday, Andrew J., Bartlett, Selena E., Colditz, Paul and Smith, Maree T. (1999) Brain region-specific studies of the excitatory behavioral effects of morphine-3-glucuronide. Life Sciences, 65 2: 225-236. 43   20
Smith, M. T., Wright, A. W., Williams, B., Stuart, G. and Cramond, T. R. (1999) Cerebrospinal fluid and plasma concentrations of morphine, morphine-3-glucuronide, and morphine-6-glucuronide in patients before and after initiation of intracerebroventricular morphine for cancer pain management. Anesthesia and analgesia, 88 1: 109-116. 60   14
Smith, MT and de la Iglesia, FA (2005) Co-administration of oxycodone and morphine and analgesic synergy re-examined. British Journal of Clinical Pharmacology, 59 4: 486-487. 26    
Smith, M. T. (2006). Combining opioids - Preclinical and clinical studies. In: , Proceedings of the 7th Biennial Conference of the Australian and New Zealand Society of Palliative Medicine. 7th Biennial Conference of the Australian and New Zealand Society of Palliative Medicine, Newcastle, (31). 4-6 October 2006. 23    
Huang, L., Edwards, S. R. and Smith, M. T. (2004). Comparative pharmacokinetics and metabolism of subcutaneous oxycodone in male dark agouti relative to sprague-dawley rats. In: Warwick P. Anderson, 8th World Congress on Clinical Pharmacology & Therapeutics - Abstracts. CTP 2004, Brisbane, (254-254). 1-6 August 2004. 61    
Huang, L., Edwards, S. R. and Smith, M. T. (2005) Comparison of the pharmacokinetics of oxycodone and noroxycodone in male dark agouti and Sprague-Dawley rats: Influence of streptozotocin-induced diabetes. Pharmaceutical Research, 22 9: 1489-1498. 115   6
Edwards, S. R. and Smith, M. T. (2004). Determination of morphine, oxycodone, morphine-3-glucuronide, & noroxycodone concentrations in rat serum by liquid chromatography (LC) - electrospray mass spectrometry (EMS). In: Warwick P. Anderson, 8th World Conference on Clinical Pharmacology & Therapeutics 2004 - Abstracts. CPT2004, Brisbane, (152-152). 1-6 August 2004. 142    
Patterson, M., Ross, F. B. and Smith, M. T. (2001). Differential changes in the potency of supraspinally administered oxycodone relative to morphine for the alleviation of tactile allodynia in adult male Dark Agouti rats with streptozotocin-induced diabetes. In ASCEPT Annual Scientific Meeting, 3 - 5 December, 2001, (80-80), Dunedin, New Zealand. 12    
He, H., Friese, M. E. J., Heckenberg, N. R. and Rubinsztein-Dunlop, H. (2003). Direct Observation of Transfer of Angular Momentum to Absorptive Particles from a Laser Beam with a Phase Singularity. In l. Allen, S. M. Barnett and M. J. Padgett (Ed.), Optical Angular Momentum (pp. 199-202) Boca Raton, FL, U.S.A.: CRC Press. 26    
Wells, J. A., Punjanon, T. and Smith, M. T. (2002). Electrolyte removal from artificial CSF by HPLC to restore ESI-MS/MS signal intensity in quantification of morphine and its glucuronide metabolites. In: , Abstracts 10th World Congress on Pain. 10th World Congress on Pain, San Diego, (59-59). 17-22 Aug. 2002. 40    
Wells, J. A., Punjanon, T., Wright, A. W. and Smith, M. T. (2001). Electrolyte removal is essential for optimizing ESI-MS/MS signal intensity for the quantification of morphine and morphine-3-glucuronide in samples of rat brain microdialysate. In Annual Scientific Meeting of ASCEPT 2001, 3 - 5 December, 2001, (84-84), Dunedin, New Zealand. 34    
Nissen, L., Mattiazzi, A., Smith, M. T., Moore, B., Williams, B. and Cramond, T. R. (2001). Follow-up audit of analgesic prescribing and use at the Multidisciplinary Pain Centre at Royal Brisbane Hospital: Temporal changes in anticonvulsant prescribing from 1999 to 2000. In: , Proceedings of 22nd Annual Scientific Meeting of Australian Pain Society 2001. 22nd Annual Scientific Meeting of Australian Pain Society 2001, Cairns, Qld, (92-93). 8 - 12 April, 2001. 35    
Hanmandlu, M., Susan, S., Madasu, V.K. and Lovell, B.C. (2008). Fuzzy Co-Clustering of Medical Images using Bacterial Foraging. In: Irie, K. and Pairman, D., 2008 23rd International Conference Image and Vision Computing New Zealand. Image and Vision Computing New Zealand 2008, Lincoln University, New Zealand, (1-6). 26-28 November, 2008. 24    
Smith, M. T. (2001). Heterodimeric opioid receptors: Implications for practice?. In: J. O'Callaghan, Proceedings of the 22nd Annual Scientific Meeting of the Australian Pain Society, 2001.. From Science to Practice, 22nd Annual Scientific Meeting of Australian Pain Society, Cairns, Qld, (56-57). 8-12 Apr 2001. 9    
Smith, M. T. (2001). Heterodimeric opioid receptors: Novel targets for a new generation of opioid analgesics.. In: D. Tracey, C. Belmonte, B. Sessle and J. Carmody, Proceedings of IUPS Satellite Symposium on Pain Mechanisms. IUPS Satellite Symposium on Pain Mechanisms, The Australian Museum, Sydney, (27-27). 19-22 Aug 2001. 30    
Roy, S., Wyse, B. and Hancock, J. F. (2002) H-Ras signaling and K-Ras signaling are differentially dependent on endocytosis. Molecular And Cellular Biology, 22 14: 5128-5140. 9   67
Wright, AWE, Nocente, ML and Smith, MT (1998) Hydromorphone-3-glucuronide: Biochemical synthesis and preliminary pharmacological evaluation. Life Sciences, 63 : 401-411. 113   20
Wright, AWE and Smith, MT (1998) Improved one-step solid-phase extraction method for morphine, morphine-3-glucuronide, and morphine-6-glucuronide from plasma and quantitation using high-performance liquid chromatography with electrochemical detection. Therapeutic Drug Monitoring, 20 : 215-218. 152   11
Nielsen, C. K., Ross, F. B. and Smith, M. T. (2000) Incomplete, asymmetric, and route-dependent cross-tolerance between oxycodone and morphine in the Dark Agouti rat. Journal of Pharmacology and Experimental Therapeutics, 295 : 91-99. 71   23
Ross, F. B., Saini, K. and Smith, M. T. (2001). Increased potency of single doses of subcutaneous oxycodone, but not morphine, in Dark Agouti rats with a chronic constriction injury (CCI) of the sciatic nerve relative to control rats.. In: J. O'Callaghan, Proceedings of 22nd Annual Scientific Meeting of Australian Pain Society. 22nd Annual Scientific Meeting of Australian Pain Society, Cairns, Qld, (37-37). 8-12 April 2001. 37    
Le, L., Chmura, P., Mather, L. E. and Smith, M. T. (2001). Influence of oestradiol pretreatment of adult male rats on levels of antinociception evoked by chronically infused intravenous morphine. In Annual Scientific Meeting of ASCEPT, 3 - 5 December, 2001, (79-79), Dunedin, New Zealand. 23    
Carozzi, A. J., Roy, S., Morrow, I. C., Pol, A., Wyse, B., Clyde-Smith, J., Prior, I. A., Nixon, S. J., Hancock, J. F. and Parton, R. G. (2002) Inhibition of lipid raft-dependent signaling by a dystrophy-associated mutant of caveolin-3. Journal of Biological Chemistry, 277 20: 17944-17949. 15   32
Smith, M. T., Nielsen, C. K., Hwang, J. C., Kydd, S., Wyse, B. D., Lewis, R. J. and Drinkwater, R. D. (2005). Intrathecal XEN2174 produces significant anti-allodynia in morphine-tolerant rats using the CCI-model of persistent neuropathic pain. In 11th World Congress on Pain, 21-26 August 2005, (265-265), Sydney, Australia. 48    
Tan, S., Wyse, B. D., Duffull, S. B. and Smith, M. T. (2005). Investigation of temporal changes in the anti-allodynic effectiveness of chronically administered gabapentin in a rat model of neuropathic pain. In: , Abstract book of 11th World Congress on Pain. 11th World Congress on Pain, Sydney, (74-P51). 21-26 August 2005. 10    
Wyse, B. D., Hwang, J. C., Kydd, S., Patterson, M., Nielsen, C. K., Belyea, C., McIntosh, D. and Smith, M. T. (2005). Investigation of the anti-allodynic and anti-hyperalgesics effects of ACV1 in a rat model of neuropathic pain. In 11th World Congress on Pain, 21-26 August 2005, Sydney, Australia. 37    
Preechagoon, D, Smith, MT and Prankerd, RJ (1998) Investigation of the antinociceptive efficacy and relative potency of extended duration injectable 3-acylmorphine-6-sulfate prodrugs in rats. International Journal of Pharmaceutics, 163 : 191-201. 11   3
Smith, M. T. (2005). In vivo proof-of-concept study: Commercialisation and regulatory imperatives. In: E. A. Davis and C. G. Sobey, Abstract: Joint Annual Scientific Meeting of ASCEPT and APSA 2005. Joint Meeting of ASCEPT and APSA, Melbourne, (115). 4-7 December 2005. 30    
Tsui, D. Y., Hawes, S., Patterson, M. and Smith, M. T. (2004). Longitudinal investigation of the antinociceptive potency of oxycodone and morphine in the zucker rat. In: Anderson, Warwick P., 8th World Conference on Clinical Pharmacology and Therapeutics 2004 - Abstracts. Clinical Pharmacology and Therapeutics 2004, Brisbane, (250-250). 1-6 August, 2004. 10    
Tsui, D. Y., Hawes, S., Patterson, M. and Smith, M. T. (2003). Longitudinal investigation of the antinociceptive potency of oxycodone and morphine in the Zucker rat. In: Davis, E. A. and Sobey. C. G., E. A. Davis and C. G. Sobey, Program and Abstracts Annual Scientific Meeting 2003. Proceedings of the Annual Scientific Meeting of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists 2003. Annual Scientific Meeting of Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists 2003, Sydney, (259). 30 November - 3 December 2003. 15    
Abdallah, J. G., Schrier, R. W., Edelstein, C., Jennings, S. D., Wyse, B. and Ellison, D. H. (2001) Loop diuretic infusion increases thiazide-sensitive Na+/Cl--cotransporter abundance: Role of aldosterone. Journal of The American Society of Nephrology, 12 7: 1335-1341. 156   37
Smith, M. T. (2003) Managing diabetic neuropathy. Australian Pharmacist, 22 10: 782-787. 28    
Smith, M. T. (2003). Methods of treatment and/or prophylaxis. PCT/AU03/00336. 15    
Smith, M. T. (2003). Neurobiology of Pain: Identification of novel targets for new pain management medications. In G. Keri and I. Toth (Ed.), Molecular Pathomechanisms and New Trends in Drug Research 1 ed. (pp. 302-318) London & New York: Taylor & Francis. 66    
Smith, M. T., Fleming, J. A. and Connor, M. (2004). Opioid rotation and methadone: Pharmacokinetic considerations. In: , State of the art - Perth 2004: Programme and Abstracts. ANZCA Annual Scientific Meeting, Perth, (54-54). 1-5 May 2004. 29    
Smith, M. T. (2004). Opioids and NMDA receptors: Neuro-excitation and abnormal pain behaviours. In: , State of the art - Perth 2004: Proceedings: ANZCA Annual Scientific Meeting. ANZCA Annual Scientific Meeting, Perth, (171). 1-5 May 2004. 57    
Bubb, L. M., Keates, H. L. and Smith, M. T. (2004). Oxycodone: A dose ranging pharmacodynamic study in dogs. In: , Proc of Association of Veterinary Anaesthetists. Proc. of Assoc. of Veterinary Anaesthetists, Vienna, Austria, (106-106). 16-17 September 2004. 405    
Bubb, L. M., Keates, H. L. and Smith, M. T. (2004). Oxycodone: A dose ranging pharmacodynamic study in dogs. In: , Research Conference Proceedings 2004. Showcasing Faculty research through our postgraduates, Gatton, (11-11). 5th November 2004. 290    
Lotfipour, S., Ross, F. B., Saini, K. and Smith, M. T. (2002). Oxycodone, but not morphine, is efficacious for the relief of tactile allodynia in diabetic rats at three and six months after the induction of diabetes with streptozotocin. In: , Abstracts 10th World Congress on Pain. 10th World Congress on Pain, San Diego, (510-510). 17-22 Aug. 2002. 30    
Smith, Maree T., Ross, Fraser B., Nielsen, Carsten K. and Saini, Kamal (2001). Oxycodone has a distinctly different pharmacology from morphine. In: F. Cervero, K. Breivik and U. Lindblom, European Journal of Pain : Proceedings of the 2nd Asian-Pacific Symposium on Pain Control. 2nd Asian-Pacific Symposium on Pain Control, Sydney, Australia, (135-136). 26-28 January, 2001. 73   4
Chinh, N.T., Quang, N.Q., Thanh, N.X., Dai, B., Geue, J.P., Addison, R.S., Travers, T. and Edstein, M.D. (2008) Pharmacokinetics and Bioequivalence Evaluation of Two Fixed-Dose Tablet Formulations of Dihydroartemisinin and Piperaquine in Vietnamese Subjects. Antimicrobial Agents & Chemotherapy, 53 2: 828-831. 12    
Mannino, CA, South, SM, Inturris, CE and Quinones-Jenab, V (2005) Pharmacokinetics and effects of 17 beta-estradiol and progesterone implants in ovariectomized rats. Journal of Pain, 6 12: 809-816. 66   10
Tan, S., Duffull, S B and Smith, M T (2006). (PK)PD of the anti-allodynic effects of gabapentin and oxycodone in a neuropathic pain rodent model. In: , Proceedings of the 8th Annual Meeting of Population Approach Group Australia and New Zealand06. PAGANZ 06, Auckland, New Zealand / School of Medicine, (x-x). 7-9 Feburary 2006. 119    
Tsui, D.Y., Hawes, S., Patterson, M. and Smith, M. T. (2004). P2.3 longitudinal investigation of the comparative anti-allodynic potencies of oxycodone and morphine in the zucker rat relative to the streptozotocin-induced diabetic rat. In: , Keeping pain management relevant. 25th Annual Scientific Meeting of the Australian Pain Society, Canberra, (52-52). 7-10 March 2004. 13    
Nielsen, C., Smith, M. T. and Ross, F. B. (2001). Preliminery investigation of the ability of oxycodone to stimulate agonist-induced internalisation of the m-opioid receptor. In Annual Scientific Meeting of ASCEPT, 3 - 5 December, 2001, (79-79), Dunedin, New Zealand. 29    

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