Institute for Molecular Bioscience - Publications

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Kompella, Shiva N., Hung, Andrew, Clark, Richard J. and Adams, David J. (2013). alpha-Conotoxin Regiia Targeting Nicotinic Acetylcholine Receptors: Mutagenesis Studies Improving Selectivity and Potency. In: Abstracts of the 57th Annual Meeting of the Biophysical Society. 57th Annual Meeting of the Biophysical Society, Philadelphia Pa, (634A-634A). 02-06 February 2013. doi:10.1016/j.bpj.2012.11.3505 50   0 0
Nicke, Annette C., Wonnacott, Susan and Lewis, Richard J. (2004) alpha-conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes. European journal of biochemistry, 271 12: 2305-2319. doi:10.1111/j.1432-1033.2004.04145.x 111   81 Cited 78 times in Scopus78 3
Nicke, Annette, Samochocki, Marek, Loughnan, Marion L., Bansal, Paramjit S., Maelicke, Alfred and Lewis, Richard J. (2003) alpha-conotoxins EpI and AuIB switch subtype selectivity and activity in native versus recombinant nicotinic acetylcholine receptors. Febs Letters, 554 1-2: 219-223. doi:10.1016/S0014-5793(03)01161-X 81   36 Cited 35 times in Scopus35 0
Dutton, J. L. and Craik, D. J. (2001) Alpha-conotoxins: Nicotinic acetylcholine receptor antagonists as pharmacological tools and potential drug leads. Current Medicinal Chemistry, 8 4: 327-344. 125   79
Beyer, Renee L., Kelso, Michael J., Reid, Robert C., Le, Giang T. and Fairlie, David P. (2006). Alpha helix induction in HIV REV34-50 by N-terminal nucleators. In: Chemical Engineering News: Abstracts-232nd ACS National Meeting. 232nd ACS National Meeting, San Francisco, CA, U.S.A., (55-55). 10-14 September, 2006. doi:10.1021/cen-v084n034.p055 58   0
Ma, M. T., Hoang, H. N., Beyer, R. L., Bryant, G. K., Appleton, T. G. and Fairlie, D. (2005). Alpha-helix induction in short peptides using metal clips. In: International Chemical Congress of Pacific Basin Societies (Pacifichem2005). International Chemical Congress of Pacific Basin Societies (Pacifichem2005), Honolulu, Hawaii, (xx-xx). 15 - 20 December 2005. 104  
Kelso, Michael J., Beyer, Renée L., Hoang, Huy N., Lakdawala, Ami S., Snyder, James P., Oliver, Warren V., Robertson, Tom A., Appleton, Trevor G. and Fairlie, David P. (2004) Alpha-turn mimetics: short peptide alpha-Helices composed of cyclic metallopentapeptide modules. Journal of The American Chemical Society, 126 15: 4828-4842. doi:10.1021/ja037980i 297   64 Cited 66 times in Scopus66 0
Brown, R. J., Millard, K. N., Nielsen, K. J. and Waters, M. J. (2001). Alteration of growth hormone receptor transmembrane. In: C. Scheck, Proceedings of the Endocrine Society 83rd Annual Meeting. 83rd Annual Meeting of the Endocrine Society, Denver, USA, (179-179). 20-23 June 2001. 58  
Scheepens, A., Sirimanne, E., Beilharz, E., Breier, B. H., Waters, M. J., Gluckman, P. D. and Williams, C. E. (1999) Alterations in the neural growth hormone axis following hypoxic-ischemic brain injury. Molecular Brain Research, 68 1-2: 88-100. doi:10.1016/S0169-328X(99)00051-0 104   45 Cited 53 times in Scopus53 0
Beaumont, K. A., Newton, R. A., Smit, D. J., Leonard, J. H., Stow, J. L. and Sturm, R. A. (2005) Altered cell surface expression of human MC1R variant receptor alleles associated with red hair and skin cancer risk. Human Molecular Genetics, 14 15: 2145-2154. doi:10.1093/hmg/ddi219 106   90 Cited 103 times in Scopus103 1
Svingen, T and Tonissen, KF (2003) Altered HOX gene expression in human skin and breast cancer cells. Cancer Biology & Therapy, 2 5: 518-523. doi:10.4161/cbt.2.5.441 54   26 Cited 26 times in Scopus26 0
Schirra, Horst Joachim, Anderson, Cameron G., Wilson, William J., Kerr, Linda, Craik, David J., Waters, Michael J. and Lichanska, Agnieszka M. (2008) Altered metabolism of growth hormone receptor mutant mice: a combined NMR metabonomics and microarray study. PLoS One, 3 7: e2764-1-e2764-15. doi:10.1371/journal.pone.0002764 120   19 Cited 22 times in Scopus22 0
Wells, C. A., Chalk, A. M., Forrest, A., Taylor, D., Waddell, N., Schroder, K., Himes, S. R., Faulkner, G., Lo, S., Kasukawa, T., Kawaji, H., Kai, C., Kawai, J., Katayama, S., Carninci, P., Hayashizaki, Y., Hume, D. A. and Grimmond, S. M. (2006) Alternate transcription of the Toll-like receptor signaling cascade. Genome Biology, 7 2: R10.1-R10.17. doi:10.1186/gb-2006-7-2-r10 90   35 Cited 43 times in Scopus43 0
Zou, J., Liao, X. Z., Cockayne, D. J. H. and Jiang, Z. M. (2002) Alternative mechanism for misfit dislocation generation during high-temperature Ge(Si)/Si(001) island growth. Applied Physics Letters, 81 11: 1996-1998. doi:10.1063/1.1506414 111   23 Cited 20 times in Scopus20 0
Schroder, Wayne, Cloonan, Nicole, Bushell, Gillian and Sculley, Tom (2004) Alternative polyadenylation and splicing of mRNAs transcribed from the human Sin1 gene. Gene, 339 1: 17-23. doi:10.1016/j.gene.2004.07.001 58   22 Cited 20 times in Scopus20 3
Kimura, Takashi, Lueck, John D., Harvey, Peta J., Pace, Suzy M., Ikemoto, Noriaki, Casarotto, Marco G., Kirksen, Robert T. and Dulhunty, Angela F. (2009) Alternative splicing of RyR1 alters the efficacy of skeletal EC coupling. Cell Calcium, 45 3: 264-274. doi:10.1016/j.ceca.2008.11.005 46   28 Cited 29 times in Scopus29 0
Delaney, Stephen J., Koopman, Peter, Lovelock, Paul K. and Wainwright, Brandon J. (1994) Alternative splicing of the first nucleotide binding fold of CFTR in mouse testes is associated with specific stages of spermatogenesis. Genomics, 20 3: 517-518. doi:10.1006/geno.1994.1214 55   7 Cited 8 times in Scopus8 0
Huerta-Sanchez, Emilia, Jin, Xin, Asan, Bianba, Zhuoma, Peter, Benjamin M., Vinckenbosch, Nicolas, Liang, Yu, Yi, Xin, He, Mingze, Somel, Mehmet, Ni, Peixiang, Wang, Bo, Ou, Xiaohua, Huasang, Luosang, Jiangbai, Cuo, Zha Xi Ping, Li, Kui, Gao, Guoyi, Yin, Ye, Wang, Wei, Zhang, Xiuqing, Xu, Xun, Yang, Huanming, Li, Yingrui, Wang, Jian, Wang, Jun and Nielsen, Rasmus (2014) Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA. Nature, 512 7513: 194-197. doi:10.1038/nature13408 8   55 Cited 59 times in Scopus59 590
Maguire, David J., Oey, Harald and McCabe, Michael (2006) ALU sequences in the human respirome. Advances in Experimental Medicine & Biology, 578 3: 73-79. doi:10.1007/0-387-29540-2_12 104   0 0 0
Sasmono, R. T., Oceandy, D., Pollard, J. W., Tong, W., Pavli, P., Wainwright, B. J., Ostrowski, M. C., Himes, S. R. and Hume, D. A. (2003) A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse. Blood, 101 3: 1155-1163. doi:10.1182/blood-2002-02-1569 171   279 Cited 288 times in Scopus288 0
Ewen, Katherine, Jackson, Andrew, Wilhelm, Dagmar and Koopman, Peter (2010) A male-specific role for p38 mitogen-activated protein kinase in germ cell sex differentiation in mice. Biology of Reproduction, 83 6: 1005-1014. doi:10.1095/biolreprod.110.086801 74   9 Cited 10 times in Scopus10 0
Kent, Jill, Wheatley, Susan C., Andrews, Jane E., Sinclair, Andrew H. and Koopman, Peter (1996) A male-specific role for SOX9 in vertebrate sex determination. Development, 122 9: 2813-2822. 71   495 Cited 508 times in Scopus508
Khor, Chiea C., Chapman, Stephen J., Vannberg, Fredrik O., Dunne, Aisling, Murphy, Caroline, Ling, Edmund Y., Frodsham, Angela J., Walley, Andrew J., Kyrieleis, Otto, Khan, Amir and et al. (2007) A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis. Nature Genetics, 39 4: 523-528. doi:10.1038/ng1976 120   267 Cited 280 times in Scopus280 17
Harsha, H. C., Suresh, Shubha, Amanchy, Ramars, Deshpande, Nandan, Shanker, K., Yatish, A. J., Muthusamy, Babylakshmi, Vrushabendra, B. M., Rashmi, B. P., Chandrika, K. N., Padma, N., Sharma, Salil, Badano, Jose L., Ramya M. A., Nagaraj, S. H., Peri, Suraj, Choudhury, Dipanwita Roy, Kavitha, M. P., Saravana, R., Niranjan, Vidya, Gandhi, T. K. B., Ghosh, Neelanjana, Chandran, Sreenath, Menezes, Minal, Joy, Mary, Mohan, S. Sujatha, Katsanis, Nicholas, Deshpande, Krishna S., Raghothama, Chaerkady, Prasad, C. K. and Pandey, Akhilesh (2005) A manually curated functional annotation of the human X chromosome. Nature Genetics, 37 4: 331-332. doi:10.1038/ng0405-331 84   5 Cited 10 times in Scopus10 0
Keys, Janelle R., Tallack, Michael R., Zhan, Ye, Papathanasiou, Peter, Doodnow, Christopher C., Gaensler, Karin M., Crossley, Merlin, Dekker, Job and Perkins, Andrew C. (2008) A mechanism for Ikaros regulation of human globin gene switching. British Journal of Haematology, 141 3: 398-406. doi:10.1111/j.1365-2141.2008.07065.x 58   23 Cited 26 times in Scopus26 0
Budnar S. and Yap A.S. (2013) A mechanobiological perspective on cadherins and the actin-myosin cytoskeleton. F1000 Prime Reports, 5 35: 35.1-35.6. doi:10.12703/P5-35 52   Cited 7 times in Scopus7 0
Cowieson, N. P., Wensley, B., Robin, G., Guncar, G., Forwood, J. K., Hume, D. A., Kobe, B. and Martin, J. L. (2008). A medium or high throughput protein refolding assay. In Bostjan Kobe, Mitchell Guss and Thomas Huber (Ed.), Structural Proteomics: High throughput Methods (pp. 269-275) USA: Humana Press. 104  
Sturm, Richard A., Bisshop, Fiona, Takahashi, Hiroyuki and Parsons, Peter G. (1991) A melanoma octamer binding protein is responsive to differentiating agents. Cell Growth & Differentiation, 2 10: 519-524. 37   32 Cited 23 times in Scopus23
Craik, D. J. (2007). American Peptide Society - 20th Symposium: Peptide vaccine and drug development. In: American Peptide Society: 20th Symposium. American Peptide Society: 20th Symposium, Montreal, Canada, (621-625). 26-30 June 2007. 119   1 0
Liu, Ganqiang, Mattick, John S. and Taft, Ryan (2013) A meta-analysis of the genomic and transcriptomic composition of complex life. Cell Cycle, 12 13: 2061-2072. doi:10.4161/cc.25134 45   23 Cited 23 times in Scopus23 0
Mattick, J. S., Gagen, M. J. and Stanley, S. (2003). A method for identifying effector molecules for gene network integration. WO 03/025229 A1. 50  
Landsberg, M. J., Bond, J., Gee, C. L., Martin, J. L. and Hankamer, B. (2006) A method for screening the temperature dependence of three-dimensional crystal formation. Acta Crystallographica Section D: Biological Crystallography, 62 559-562. doi:10.1107/s0907444906006093 133   7 Cited 6 times in Scopus6 0
Huang, Bixing, Whitchurch, Cynthia B., Croft, Larry, Beatson, Scott A. and Mattick, John S. (2000) A minimal tiling path cosmid library for functional analysis of the Pseudomonas aeruginosa PAO1 genome. Microbial and Comparative Genomics, 5 4: 189-203. doi:10.1089/omi.1.2000.5.189 77   Cited 15 times in Scopus15 0
Leong, Lex E. X., Denman, Stuart E., Hugenholtz, Philip and McSweeney, Christopher S. (2015) Amino acid and peptide utilization profiles of the fluoroacetate-degrading bacterium synergistetes strain MFA1 under varying conditions. Microbial Ecology, 71 2: 494-504. doi:10.1007/s00248-015-0641-4 23   0 1
Ghosh, S. K., Somanadhan, B., Butler, M. S. and Lear, M. J. (2010). Amino acid stereochemical assignment and total synthesis of a natural anti-malarial peptide. In: Abstracts of Papers of the American Chemical Society. unknown, unknown, (). unknown. 40   0
Becker, Bernd and Cooper, Matthew A. (2013) Aminoglycoside antibiotics in the 21st century. ACS Chemical Biology, 8 1: 105-115. doi:10.1021/cb3005116 72   40 Cited 48 times in Scopus48 0
Kalebina, Tatyana S., Sokolov, Sviatoslav S., Selyakh, Irina O., Vanichkina, Darya P. and Severin, Fedor F. (2015) Amiodarone induces cell wall channel formation in yeast Hansenula polymorpha. SpringerPlus, 4 453: . doi:10.1186/s40064-015-1185-2 19   0 0 0
Ng, SK, McLachlan, GJ, Wang, K, Jones, LBT and Ng, SW (2006) A Mixture model with random-effects components for clustering correlated gene-expression profiles. Bioinformatics, 22 14: 1745-1752. doi:10.1093/bioinformatics/btl165 1313   76 Cited 83 times in Scopus83 0
Tedford, Hugo W., Maggio, Francesco, Reenan, Robert A. and King, Glenn F. (2007). A model genetic system for testing the in vivo function of peptide toxins. In: Ronald J. Nachman, Invertebrate Neuropeptides VII: Invertebrate Neuropeptide Conference 2006. 7th Invertebrate Neuropeptide Conference (INC2006), Guanajuato, Mexico, (51-56). 2006. doi:10.1016/j.peptides.2006.08.026 56   8 Cited 6 times in Scopus6 0
Eckle, Sidonia B.G., Birkinshaw, Richard W., Kostenko, Lyudmila, Corbett, Alexandra J., McWilliam, Hamish E. G., Reantragoon, Rangsima, Chen, Zhenjun, Gherardin, Nicholas A., Beddoe, Travis, Liu, Ligong, Patel, Onisha, Meehan, Bronwyn, Fairlie, David P., Villadangos, Jose A., Godfrey, Dale I., Kjer-Nielsen, Lars, McCluskey, James and Rossjohn, Jamie (2014) A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells. Journal of Experimental Medicine, 211 8: 1585-1600. doi:10.1084/jem.20140484 34   24 Cited 24 times in Scopus24 2
McDevitt, Christopher A., Ogunniyi, Abiodun D., Valkov, Eugene, Lawrence, Michael C., Kobe, Bostjan, McEwan, Alastair G. and Paton, James C. (2011) A molecular mechanism for bacterial susceptibility to zinc. PLoS Pathogens, 7 11: e1002357.1-e1002357.9. doi:10.1371/journal.ppat.1002357 124   76 Cited 84 times in Scopus84 11
Hodgson, S. S., Francois, M. and Khosrotehrani, K. (2012). A mouse model for in vivo quantitative monitoring of Wnt/b-catenin signaling in skin reveals hair cycle dynamics in sox18 mutant mice. In: Abstracts 22nd Annual Meeting of the European Tissue Repair Society. 22nd Annual Meeting of the European Tissue Repair Society, Athens, Greece, (A59-A59). October 4–5 2012. doi:10.1111/j.1524-475X.2012.00835.x 56   0 0
Ovenden, SPB, Capon, RJ, Lacey, E, Gill, JH, Friedel, T and Wadsworth, D (1999) Amphilactams A-D: Novel nematocides from southern Australian marine sponges of the genus Amphimedon. Journal of Organic Chemistry, 64 4: 1140-1144. doi:10.1021/jo981377e 91   21 Cited 23 times in Scopus23 0
Qin, Ling, Raggatt, L., Li, X., Tamasi, J., Feyen, J. H. M. and Partridge, N. C. (2003). Amphiregulin: A possible mediator of parathyroid hormone's anabolic actions in bone. In: Journal of Bone and Mineral Research: 25th Annual Meeting of the American Society for Bone and Mineral Research. 25th Annual Meeting of the American Society for Bone and Mineral Research, Minneapolis, Minnesota, U.S.A., (S100-S100). 19-23 September, 2003. 89   0
Qin, L., Tamasi, J., Raggatt, L., Li, X., Feyen, J., Lee, D., DiCicco-Bloom, E. and Partridge, N. C. (2004). Amphiregulin is a novel growth factor in bone stimulated by parathyroid hormone and required for normal bone development. In: FASEB Journal. Annual Meeting of the American Society for Biochemistry-and-Molecular-Biology/8th Congress of the International Union for Biochemistry and Molecular Biology, Boston, MA, USA, (C299-C299). 12-16 June 2004. 69  
Qin, Ling, Tamasi, Joseph, Raggatt, Liza, Li, Xin, Feyen, Jean H. M., DiCicco-Bloom|, Emanuel and Partridge, Nicola C. (2005) Amphiregulin Is a Novel Growth Factor Involved in Normal Bone Development and in the Cellular Response to Parathyroid Hormone Stimulation. Journal of Biological Chemistry, 280 5: 3974-3981. doi:10.1074/jbc.M409807200 63   50 Cited 53 times in Scopus53 0
Herms, Albert, Bosch, Marta, Reddy, Babu J. N., Schieber, Nicole L., Fajardo, Alba, Ruperez, Celia, Fernandez-Vidal, Andrea, Ferguson, Charles, Rentero, Carles, Tebar, Francesc, Enrich, Carlos, Parton, Robert G., Gross, Steven P. and Pol, Albert (2015) AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation. Nature Communications, 6 7176.1-7176.14. doi:10.1038/ncomms8176 9   1 Cited 2 times in Scopus2 8
Thomson, David A. C., Dimitrov, Krassen and Cooper, Matthew A. (2011) Amplification free detection of Herpes Simplex Virus DNA. Analyst, 136 8: 1599-1607. doi:10.1039/c0an01021a 94   8 Cited 8 times in Scopus8 0
Vetter, Irina, Hein, Alexander, Sattler, Simon, Hessler, Sabine, Touska, Filip, Bressan, Elisangela, Parra, Andres, Hager, Ulrich, Leffler, Andreas, Boukalova, Stepana, Nissen, Matthias, Lewis, Richard J., Belmonte, Carlos, Alzheimer, Christian, Huth, Tobias, Vlachova, Viktorie, Reeh, Peter W. and Zimmermann, Katharina (2013) Amplified Cold Transduction in Native Nociceptors by M-Channel Inhibition. Journal of Neuroscience, 33 42: 16627-16641. doi:10.1523/JNEUROSCI.1473-13.2013 71   7 Cited 8 times in Scopus8 1
White, Stefan, Hewitt, Jacqueline, Turbitt, Erin, van der Zwan, Yvonne, Hersmus, Remko, Drop, Stenvert, Koopman, Peter, Harley, Vincent, Cools, Martine, Looijenga, Leendert and Sinclair. Andrew (2012) A multi-exon deletion within WWOX is associated with a 46,XY disorder of sex development. European Journal of Human Genetics, 20 3: 348-351. doi:10.1038/ejhg.2011.204 101   11 Cited 14 times in Scopus14 0

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